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How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.

6 Nov 2024

Exploring the circadian influence of immune cells on metabolic health and fat storage

Recent research reveals that the immune system interacts with the body's internal clock, influencing both fat storage and temperature regulation. These insights carry substantial implications for individuals with irregular work, eating, or sleep patterns driven by the demands of modern life.

6 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

The crucial role of sleep in heart healing

Researchers examine how sleep impacts inflammation and recovery following a heart attack.

31 Oct 2024

Boosting Treg cells shows promise in preventing recurrent pregnancy loss

Recurrent pregnancy loss can be devastating and exert a major impact on women, their partners, and society more broadly, but currently there are few options for effective therapies.

29 Oct 2024

Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Chronic active antibody-mediated rejection (caAMR) is a common cause of allograft loss after transplantation, with no approved therapies. Clazakizumab, a monoclonal antibody that targets the inflammatory cytokine interleukin-6 (IL-6), stabilized kidney transplant recipients' kidney function in a phase 2 trial.

27 Oct 2024

Gut health and diet: Keys to treating acne, alopecia, and dermatitis

Consuming diets rich in fiber, antioxidants, and phytonutrients, combined with the use of probiotics, synbiotics, and postbiotics, improves overall skin health.

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

Understanding cardiovascular risks in endometriosis patients

Endometriosis increases the risk of cardiovascular events.

18 Oct 2024

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

The connection between gum disease and thrombosis underscores the role of oral health in reducing thrombotic disease risk and improving patient outcomes.

17 Oct 2024

Microplastics accelerate aging and inflammation in fat tissue, increasing risk of chronic disease

Researchers investigate the effects of microplastic exposure on the normal aging and function of adipose tissue.

16 Oct 2024

Distinct immune profiles linked to adverse reactions from immunotherapy

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

15 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

Genetics identified as key factor in gout development

A major international study has found gout is a chronic illness where genetics is a major cause, rather than lifestyle choices of the sufferer.

15 Oct 2024

Dietary inflammation linked to higher mortality risk in coronary heart disease patients

Researchers examine the association between dietary inflammation and coronary heart disease.

15 Oct 2024

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

Researchers uncover how senescent cells can both harm and heal in liver disease

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their distinct roles in liver fibrosis and repair. Senescent macrophages promote fibrosis, while endothelial cells aid in tissue recovery.

7 Oct 2024

New platform mimics immune interactions to boost cancer treatment

Imagine a world where your own immune cells are transformed into cancer-fighting superheroes.

7 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Interleukin News and Research

How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

Exploring the circadian influence of immune cells on metabolic health and fat storage

New therapeutic target overcomes ovarian cancer immunotherapy resistance

The crucial role of sleep in heart healing

Boosting Treg cells shows promise in preventing recurrent pregnancy loss

Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Gut health and diet: Keys to treating acne, alopecia, and dermatitis

Arthritis-style immunotherapy shows promise for heart failure

Understanding cardiovascular risks in endometriosis patients

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

Microplastics accelerate aging and inflammation in fat tissue, increasing risk of chronic disease

Distinct immune profiles linked to adverse reactions from immunotherapy

New study reveals mechanism of inflammation in lupus

Genetics identified as key factor in gout development

Dietary inflammation linked to higher mortality risk in coronary heart disease patients

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Researchers uncover how senescent cells can both harm and heal in liver disease

New platform mimics immune interactions to boost cancer treatment

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

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