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Cryo-EM reveals how proteins are protected during synthesis

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

19 Nov 2025

Automated system relies on imaging droplets of biofluids for disease diagnosis

Not long ago, the idea of diagnosing a disease with a droplet of blood was considered a pipe dream. Today, this technology could soon become a reality.

19 Nov 2025

Scientists urge careful evaluation before applying AI virtual staining in healthcare workflows

Artificial intelligence has exploded in popularity in recent years, and many proponents are excited about its potential uses in medicine: for example, processing samples quickly or identifying markers of disease that may be missed by the human eye.

18 Nov 2025

New human-cell bone marrow model offers alternative to animal experiments

Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types.

18 Nov 2025

Bruker launches xView Module for Ultima 2Pplus multiphoton microscopes

At the Neuroscience 2025 conference, Bruker Corporation today announced the release of the xView Module for Ultima 2Pplus multiphoton microscopes to significantly extend imaging scale and experiment flexibility for advanced neuroscience research.

From Bruker Nano Surfaces and Metrology 17 Nov 2025

Common malaria test gives too many inaccurate false-negative results

An international study published in the Malaria Journal claims that a widely used test for detecting malaria is delivering too many inaccurate false-negative results and is “not fit for purpose”.

17 Nov 2025

Cornell team unveils high-resolution tool for tracking kinase activity

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

13 Nov 2025

Hiiragi group and Prevedel group collaborate with Prospective Instruments to pioneer intravital multiphoton microscopy for early embryo research

Prof. Takashi Hiiragi (Hubrecht Institute), Dr. Robert Prevedel (European Molecular Biology Laboratory), and Dr. Lukas Krainer (Prospective Instruments) have launched an interdisciplinary collaboration to develop a novel intravital microscopy platform for studying mammalian embryo implantation.

13 Nov 2025

Hard water drives a surge in microplastic shedding from polyester, study finds

Researchers found that hand-washing in mineral-rich water dramatically increases microplastic fibre shedding from polyester fabrics, fragmenting fibres into shorter pieces. A two-layer PDMS coating sharply reduced shedding from green polyester but was far less effective on black polyester due to pre-existing surface finishes.

12 Nov 2025

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein, an integral step in the virus cycle.

7 Nov 2025

Scientists map kinesin-2 tail structure to understand cargo binding

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo remained a mystery. The new study provides a key piece of this puzzle by revealing the atomic-level structure of the kinesin-2 tail and its interaction with cargo and adaptor proteins.

6 Nov 2025

AI and protein language models can accelerate the design of antiviral antibodies

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

5 Nov 2025

New AI-assisted atlas can help visualize the human brain in unprecedented detail

A new AI-assisted brain atlas that can help visualize the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging.

5 Nov 2025

Opioid receptors caught in motion offering clues for safer painkillers

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was exactly what happens next.

5 Nov 2025

Breakthrough study reveals how rabies virus uses few proteins to hijack cells

New antivirals and vaccines could follow the discovery by Australian researchers of strategies used by viruses to control our cells.

5 Nov 2025

Motor protein Myosin II regulates temperature sensitivity of immune cells

Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level-until now.

4 Nov 2025

Researchers identify new molecular switch involved in programmed cell death

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

3 Nov 2025

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Scripps Research scientists receive NIH grant to unlock long-term HIV protection

Nearly 40 years after HIV was first identified, the virus continues its devastating march across the globe. Today, 38 million people live with HIV, and each year brings 1.5 million new infections and 650,000 more deaths-while nearly 10 million people still lack access to life-saving medicines.

31 Oct 2025

Scientists capture a near-continuous molecular movie of ribosome formation

Ribosomes are the cell's protein factories, which read the genetic code and assemble the proteins that every organism needs to live. But as far as how ribosomes themselves were formed, tantalizingly little was known.

30 Oct 2025