Telomerase News and Research

RSS

Trop-2 new target for anti-tumour therapy in cancer

Italian scientists announced (Monday September 24) that they have found a new and promising target for anti-tumour therapy in cancer.

25 Sep 2007

Chronic stress can steal years from caregivers' lifetimes

The chronic stress that spouses and children develop while caring for Alzheimer's disease patients may shorten the caregivers' lives by as much as four to eight years, a new study suggests.

18 Sep 2007

New clues to why persistent acid reflux can turn into cancer

New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.

13 Aug 2007

Why acid reflux sometimes turns into cancer

12 Aug 2007

Mutations in a gene that helps regulate cell division linked to inherited form of fatal lung disease

Mutations in a gene that helps regulate cell division are responsible for some inherited cases of a fatal lung disease, researchers at UT Southwestern Medical Center have found.

27 Apr 2007

Johns Hopkins team stops form of blood cancer in its tracks

A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres.

26 Apr 2007

Genetic culprits of idiopathic pulmonary fibrosis

Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease.

30 Mar 2007

Scientists step closer to understanding the relationship between aging and cancer

Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome.

6 Feb 2007

New target for cancer therapy identified by Australian researchers

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development.

21 Sep 2006

The heart can heal itself

World Congress of Cardiology Report - Despite the dramatic advances in the care of patients with cardiovascular diseases that have occurred in the second half of the 20th century, heart failure (HF) is the most common cause of death in developed nations.

5 Sep 2006

An engineered virus that tracks down and compels cancer cells to eat themselves

An engineered virus tracks down and infects the most common and deadly form of brain cancer and then kills tumor cells by forcing them to devour themselves, researchers at The University of Texas M. D. Anderson Cancer Center report.

3 May 2006

Gene therapy approach used in creating new arteries for older patients does not appear to cause cancer

"This result is an encouraging step along the road to new tissues for patients to replace those that have failed or have been destroyed due to trauma or disease," she said.

7 Mar 2006

Monotherapy phase I clinical trials of novel cytotoxics, targeted therapeutics, antimetastatic agents/angiogenesis inhibitors, and immunotherapeutics/vaccines

Numerous novel oncology agents are currently in phase I monotherapy trials. New Medicine's Oncology KnowledgeBASE (nm|OK) has updated the records of 92 such agents with preclinical or clinical results reported during the 2005 meetings of the American Association for Cancer Research (AACR)

7 Feb 2006

DNA end caps may lead to cancer treatments

The two ends of human DNA have different structures that are treated differently as a cell divides, UT Southwestern Medical Center researchers have found in a study that could help lead to cancer therapies.

7 Feb 2006

Scientists have determined the detailed structure of an essential piece of the telomerase enzyme

Scientists have determined the detailed structure of an essential piece of the telomerase enzyme, an important contributor to the vast majority of human cancers. Understanding the physical shape of the protein has led to a better understanding of how it acts to immortalize cells - and should help scientists design broadly effective cancer drugs.

5 Feb 2006

Simple urine test detects bladder cancer

According to Italian researchers a simple and accurate urine test can detect bladder cancer early and they say the test should be used on smokers and others prone to the disease.

26 Oct 2005

Measurement of telomerase activity in urine appears useful for detection of bladder cancer in men

The incidence of human bladder cancer has greatly increased over the last few decades, with more than 60,000 new cases diagnosed each year in the United States alone, and now represents the 4th most common malignancy in men and the 10th most common in women, according to background information in the article.

25 Oct 2005

Compound called GRN163L blocks lung cancer

Researchers at UT Southwestern Medical Center have found a compound that shows promise as a way to block the spread, or metastasis, of lung cancer.

1 Sep 2005

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Routinely discarded as medical waste, placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryonic stem cells, suggests a University of Pittsburgh study to be published in the journal Stem Cells and available now as an early online publication in Stem Cells Express.

10 Aug 2005

Discovery may lead to new therapies for leukemia

Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.

2 Aug 2005