Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Serum neurofilament levels can be used to differentiate between frontotemporal dementia and psychiatric disorders

Early symptoms of frontotemporal dementia are often confused with symptoms occurring in psychiatric disorders.

10 Oct 2019

Sex-specific verbal memory test cut-offs may improve amnestic MCI diagnoses

Women make up two-thirds of patients with Alzheimer's disease - so why is it that women are less likely than men to be diagnosed with its precursor, amnestic mild cognitive impairment?

9 Oct 2019

New NIH grant to support innovative skin testing approach for diagnosing Parkinson's disease

Wenquan Zou, MD, PhD, an expert in degenerative neurological diseases, along with his collaborators Shu G. Chen, PhD also from the Case Western Reserve University School of Medicine, Jiyan Ma, MD, PhD, from Van Andel Institute in Grand Rapids, Michigan, and Thomas Beach, MD, PhD, from Banner Sun Health Research Institute, Sun City, Arizona, have received a five-year, $3.6 million grant from the National Institutes of Health for diagnosing Parkinson's disease (PD) via an innovative skin testing approach.

4 Oct 2019

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

The nation has been grappling with the opioid epidemic for years - and the city of Philadelphia has been hit hard by the crisis. While data is showing slight declines in overdose deaths, the opioid crisis remains a public health emergency.

4 Oct 2019

NIH grants boost rare diseases research efforts

Of an estimated 6,500 to 7,000 known rare diseases, only a fraction - maybe 5% - have U.S. Food and Drug Administration-approved treatments.

4 Oct 2019

Quanterix announces recipients of annual Accelerator Grant Program

Quanterix Corporation, a company digitizing biomarker analysis to advance the science of precision health, today announced Shelli Kesler, Ph.

From Quanterix 3 Oct 2019

Unique biomarker in urine may offer non-invasive means of detecting prostate cancer

A research study published in the journal Neoplasia and led by principal investigator Nallasivam Palanisamy, Ph.D., associate scientist in the Vattikuti Urology Institute at Henry Ford Health System, has identified a novel prostate cancer gene fusion involving the KLK4 protein coding gene and KLKP1 pseudogene.

3 Oct 2019

New discovery could lead to better treatment and prevention of heart disease, diabetes

Researchers at Cornell University have uncovered a key step in how the human body metabolizes sugar, which could lead to better treatment and prevention of heart disease, obesity and Type 2 diabetes.

2 Oct 2019

Vitamin C improves survival rate in sepsis and acute respiratory distress syndrome (ARDS)

The body’s immune system works by protecting against disease and potentially damaging foreign bodies. In some instances, it may become impaired, leading to overreaction to infection.

1 Oct 2019

Study may lead to new approaches to treating reading deficits after stroke

A team of New Jersey stroke researchers has linked recovery of reading and language competence with cerebral blood flow in the left reading network. Their findings may contribute to new approaches to identifying and treating reading deficits after stroke.

1 Oct 2019

Nanoparticles moving through airway mucus may predict severity of COPD

In a proof-of-concept experiment, researchers from Johns Hopkins Medicine say they have successfully used microscopic man-made particles to predict the severity of patients' chronic obstructive pulmonary disease by measuring how quickly the particles move through mucus samples.

30 Sep 2019

A new method to distinguish benign and cancerous skin moles

A new study has reported a cost-effective, more accurate, and less invasive way to diagnose cancerous melanoma cells in skin tumors.

30 Sep 2019

New method can help detect melanoma cells in skin tumors

Melanoma is the least common but one of the most deadly skin cancers. It accounts for only about one percent of all cases globally, but the majority of skin cancer deaths.

30 Sep 2019

Higher levels of genetic mutations linked to improved outcomes in lung cancer patients

According to new findings by Yale Cancer Center scientists, higher levels of genetic mutations in a tumor biopsy are linked to improved clinical outcomes in patients using pembrolizumab (Keytruda) to treat non-small cell lung cancer (NSCLC).

27 Sep 2019

Cellular aging associated with structural changes in the brain

Telomeres are protective caps at the ends of chromosomes that become shorter with each cell division. If they become so short that the genes they protect could be damaged, the cell stops dividing and renewing.

27 Sep 2019

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

A secondary analysis of a recent clinical trial that changed the standard of care for men with recurring prostate cancer finds long-term hormone therapy does more harm than good for many men and calls for rethinking treatment guidelines based on a patient's post-operative prostate-specific antigen (PSA) level.

26 Sep 2019

Study shows miRNAs in semen as non-invasive biomarkers for prostate cancer

Researchers of the Human Molecular Genetics group at the Bellvitge Biomedical Research Institute, led by Dr. Sara Larriba, in collaboration with Dr. Francesc Vigués and Dr. Manel Castells of the Urology Service of Bellvitge University Hospital, show the usefulness of certain molecules, the miRNAs in semen, as non-invasive biomarkers for prostate cancer.

26 Sep 2019

Metabolite may predict cancer versus autism risk in PTEN patients

In a new study published in American Journal of Human Genetics, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may predict whether individuals with PTEN mutations will develop cancer or autism spectrum disorder.

26 Sep 2019

Researchers identify novel genetic variants linked to plasma lipid levels and cardiovascular risk

An international research team has identified several novel genetic variants associated with plasma levels of lipid species and cardiovascular disease risk in humans.

26 Sep 2019

New lab-on-a-chip system quickly identifies health aspects of a person's immune system

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a lab-on-a-chip system that can identify the health aspects of a person's immune system from a drop of their blood, within minutes.

25 Sep 2019

Biomarker News and Research

Further Reading

Serum neurofilament levels can be used to differentiate between frontotemporal dementia and psychiatric disorders

Sex-specific verbal memory test cut-offs may improve amnestic MCI diagnoses

New NIH grant to support innovative skin testing approach for diagnosing Parkinson's disease

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

NIH grants boost rare diseases research efforts

Quanterix announces recipients of annual Accelerator Grant Program

Unique biomarker in urine may offer non-invasive means of detecting prostate cancer

New discovery could lead to better treatment and prevention of heart disease, diabetes

Vitamin C improves survival rate in sepsis and acute respiratory distress syndrome (ARDS)

Study may lead to new approaches to treating reading deficits after stroke

Nanoparticles moving through airway mucus may predict severity of COPD

A new method to distinguish benign and cancerous skin moles

New method can help detect melanoma cells in skin tumors

Higher levels of genetic mutations linked to improved outcomes in lung cancer patients

Cellular aging associated with structural changes in the brain

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

Study shows miRNAs in semen as non-invasive biomarkers for prostate cancer

Metabolite may predict cancer versus autism risk in PTEN patients

Researchers identify novel genetic variants linked to plasma lipid levels and cardiovascular risk

New lab-on-a-chip system quickly identifies health aspects of a person's immune system

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