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Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer's levels of glucose as well as lactate, alcohol or caffeine.

15 Feb 2021

Star-shaped brain cells may play a key role in stuttering

Astrocytes -- star-shaped cells in the brain that are actively involved in brain function -- may play an important role in stuttering, a study led by a University of California, Riverside, expert on stuttering has found.

12 Feb 2021

The Future of Environmental and Food Monitoring

NewsMed interviews Professor Antje Baeumner about the future of food and environmental monitoring, the subject of her 2021 Pittcon presentation.

From Pittcon 12 Feb 2021

Exercise during pregnancy may help mitigate negative effects of parental obesity in children

New research in mice suggests that exercising during pregnancy may help prevent children- especially boys- from developing health problems related to their parents' obesity. The study is published ahead of print in the Journal of Applied Physiology.

11 Feb 2021

Researchers use cachexia model to assess cancer-derived myocardial impairments

Oncotarget recently published "Evaluation of cancer-derived myocardial impairments using a mouse model" which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder.

11 Feb 2021

Study identifies new therapeutic targets for treatment of obesity and type 2 diabetes

The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake.

10 Feb 2021

Study: Children with Type 1 diabetes have lower brain volume, verbal IQ, and overall IQ

Brain volume, verbal IQ, and overall IQ are lower in children with Type 1 diabetes (T1D) than in children without diabetes, according to a new longitudinal study published in Diabetes Care, a journal of the American Diabetes Association.

10 Feb 2021

Study finds increasing death rates from heart disease in young women

A nationwide US study has found increasing death rates from heart disease in women under 65. The research is published in European Heart Journal - Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology (ESC).

10 Feb 2021

Immune responses to insulin could help identify individuals at risk for developing type 1 diabetes

Researchers from the Barbara Davis Center for Childhood Diabetes at the University of Colorado Anschutz Medical Campus have found that immune responses to insulin could help identify individuals most at risk for developing Type 1 diabetes.

9 Feb 2021

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

Older adults who are classified as having "prediabetes" due to moderately elevated measures of blood sugar usually don't go on to develop full-blown diabetes, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

8 Feb 2021

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown.

8 Feb 2021

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Scripps Research, a globally recognized nonprofit biomedical research institute, today announced a collaborative research program with Tempus, a leader in precision medicine and artificial intelligence, to develop a predictive model of glucose responses in people with and without type 2 diabetes.

4 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Researchers discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia.

1 Feb 2021

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

A new study by researchers in China and the U.S. describes a round-up of the effects of commonly used hypoglycemic drugs on the outcomes of COVID-19 in diabetic patients.

1 Feb 2021

Gestational diabetes may lead to heart disease in women during pregnancy

Women with a history of diabetes during pregnancy (gestational diabetes) are twice as likely by mid-life to develop calcium in heart arteries - a strong predictor of heart disease - even if healthy blood sugar levels were attained many years after pregnancy, according to new research published today in the American Heart Association's flagship journal Circulation.

1 Feb 2021

Researchers develop mobile EKG device that can identify patients at risk of sudden cardiac death

Researchers from Mayo Clinic and AliveCor Inc. have been using artificial intelligence (AI) to develop a mobile device that can identify certain patients at risk of sudden cardiac death.

1 Feb 2021

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

Hybrid closed-loop insulin therapy improved glycemic control in adolescents and young adults with type 1 diabetes. These outcomes, derived from the International Diabetes Closed-Loop (iDCL) Trial, are reported in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT).

27 Jan 2021

Glucose News and Research

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Star-shaped brain cells may play a key role in stuttering

The Future of Environmental and Food Monitoring

Exercise during pregnancy may help mitigate negative effects of parental obesity in children

Researchers use cachexia model to assess cancer-derived myocardial impairments

Study identifies new therapeutic targets for treatment of obesity and type 2 diabetes

Study: Children with Type 1 diabetes have lower brain volume, verbal IQ, and overall IQ

Study finds increasing death rates from heart disease in young women

Immune responses to insulin could help identify individuals at risk for developing type 1 diabetes

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

New process separates beneficial glucocorticoids from unwanted side-effects

Researchers discover novel metabolic gatekeeper mechanism for leukemia

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

Gestational diabetes may lead to heart disease in women during pregnancy

Researchers develop mobile EKG device that can identify patients at risk of sudden cardiac death

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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