RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

In a new study, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (NSP13) at high spatio-temporal resolution.

13 Oct 2022

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral DNA vaccine to target the SARS-CoV-2 Delta variant, and tested its cross-protection efficacy using mice models.

13 Oct 2022

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis.

13 Oct 2022

The impact of humidity levels on viral transmission and viability

A recent PLoS ONE study reviewed the impact of humidity on virus transmission and its viability.

13 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

Researchers develop a causal model to assess the dependence of viral loads of patients infected with COVID-19 on age

Researchers developed a causal model to analyze SARS-CoV-2 viral load distribution as a function of patients’ age.

12 Oct 2022

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers developed a RT-qPCR system to identify SARS-CoV-2 Omicron variants of concern.

12 Oct 2022

Precise DNA cleavage using new CRISPR-Cas approach

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies.

11 Oct 2022

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

"Smart surveillance" for viral spillover needed to lessen the consequences of next pandemic

"Smart surveillance" for viral spillover from animals to humans, targeted preparedness and drug and vaccine research, and worldwide cooperation on surveillance and stopping disease spread are required to reduce deaths and lessen the economic consequences of the next pandemic, according to an international team of scientists.

10 Oct 2022

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

10 Oct 2022

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

The Independent Task Force on COVID-19 and other Pandemics (www.independentcovidtaskforce.org) announced that their report "Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA Viruses" has been published in the Proceedings of the National Academy of Sciences.

10 Oct 2022

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

10 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet.

7 Oct 2022

RNA News and Research

Further Reading

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

The impact of humidity levels on viral transmission and viability

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

Researchers develop a causal model to assess the dependence of viral loads of patients infected with COVID-19 on age

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Precise DNA cleavage using new CRISPR-Cas approach

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

"Smart surveillance" for viral spillover needed to lessen the consequences of next pandemic

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

Chronic liver disease in COVID-19 patients

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo