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Cell Medica treats first pediatric patient in ASPIRE Trial

Cell Medica today announced the treatment of the first patient in the ASPIRE Trial, an early stage Phase I/II clinical study investigating the safety and efficacy of Cytovir ADV for the treatment of adenovirus infections in immunosuppressed pediatric patients following bone marrow transplantation.

8 May 2013

EPSRC-funded study explores feasibility of using natural fibres for cartilage repair

Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage. Stem cells offer a promising way forward but a key challenge has been to design a 'smart material' that is biologically effective for cartilage tissue regeneration. Now researchers have identified a blend of naturally occurring fibres such as cellulose and silk that makes progress towards affordable and effective cell-based therapy for cartilage repair a step closer

8 May 2013

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot - and without the unwanted side effects.

8 May 2013

Addressing sleep hygiene prior to CPAP initiation may help improve adherence

A new study suggests that regularity of bedtime prior to initiation of continuous positive airway pressure therapy is an important factor that may influence treatment compliance in adults with obstructive sleep apnea.

8 May 2013

$Study shows VATS-LCSD can help children with refractory cardiac arrhythmias$

Study shows VATS-LCSD can help children with refractory cardiac arrhythmias

Inherited ventricular arrhythmias are an important cause of morbidity and sudden cardiac death in children who have structurally normal hearts. Despite conventional medical therapy, some of these children remain symptomatic with recurrent life-threatening arrhythmias, syncope, or frequent discharges from implantable cardioverter defibrillators.

8 May 2013

Testing Stat5 gene amplification in prostate cancer patients could provide powerful therapy: Study

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5.

8 May 2013

Brain scan studies may provide clues about how the device improves depression

For nearly a decade, doctors have used an implanted electronic stimulator to treat severe depression in people who don't respond to standard antidepressant therapy.

8 May 2013

New study examines treatment delays in black women with breast cancer

Black women with breast cancer were found to be three times more likely than their white counterparts to delay treatment for more than 90 days - a time delay associated with increased deaths from the disease, according to a new study led by researchers at Georgetown Lombardi Comprehensive Cancer Center.

8 May 2013

Cubist receives Fast Track designation from FDA for late-stage antibiotic candidate

Cubist Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted the Company's late-stage antibiotic candidate ceftolozane/tazobactam (CXA-201) Fast Track status in the previously granted Qualified Infectious Disease Product indications, Hospital-Acquired Bacterial Pneumonia/Ventilator-Associated Bacterial Pneumonia and Complicated Urinary Tract Infections.

8 May 2013

New guidelines for radiation therapy after prostatectomy

Based on a major effort co-led by Richard Valicenti, UC Davis Department of Radiation Oncology Professor and Chair, the nation's leading urological and radiation oncology organizations today announced a new guideline for radiation therapy after prostatectomy.

8 May 2013

BIOTRONIK receives FDA approval for ICD/CRT-D series

BIOTRONIK, a leading manufacturer of cardiovascular medical technology, announced that the Food and Drug Administration granted approval for its Ilesto 7 implantable cardioverter-defibrillator/cardiac resynchronization therapy defibrillator series.

8 May 2013

Clinical data of cabozantinib to be presented at ASCO meeting

Exelixis, Inc. announced today that cabozantinib will be the subject of nine separate data presentations at the upcoming 2013 Annual Meeting of the American Society of Clinical Oncology.

8 May 2013

New skin cancer drug successfully tested in humans

A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases.

8 May 2013

Study to examine role of arts, humanities in improving mental health and well-being

An innovative study led by The University of Nottingham is to investigate whether arts and humanities can help improve the mental health and well-being of patients and carers alike.

8 May 2013

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1b/2a clinical study of ISIS-STAT3Rx in patients with advanced metastatic hepatocellular carcinoma (HCC).

7 May 2013

Janssen enrolls patients in expanded access program for mantle cell lymphoma

Janssen Research & Development, LLC (Janssen) today announced patients are now enrolling in a multicenter, open-label expanded access program (EAP) in the United States for the investigational oral Bruton's Tyrosine Kinase (BTK) inhibitor ibrutinib, which is being jointly developed by Janssen and Pharmacyclics, Inc.

7 May 2013

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung.

7 May 2013

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

7 May 2013

Breast milk might prevent premature babies from deadly intestinal condition

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC in this week's online early edition of the Proceedings of the National Academy of Sciences.

7 May 2013

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Aileron Therapeutics, Inc. today announced the completion of the first-in-human study of its lead Stapled Peptide drug, ALRN-5281, a proprietary, long-acting growth-hormone-releasing hormone (GHRH) agonist for treating orphan endocrine disorders, including adult growth hormone (GH) deficiency and human immunodeficiency virus (HIV) lipodystrophy, as well as broader patient populations involving a wide variety of metabolic/endocrine diseases.

7 May 2013

Therapy News and Research

Cell Medica treats first pediatric patient in ASPIRE Trial

EPSRC-funded study explores feasibility of using natural fibres for cartilage repair

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

Addressing sleep hygiene prior to CPAP initiation may help improve adherence

Study shows VATS-LCSD can help children with refractory cardiac arrhythmias

Testing Stat5 gene amplification in prostate cancer patients could provide powerful therapy: Study

Brain scan studies may provide clues about how the device improves depression

New study examines treatment delays in black women with breast cancer

Cubist receives Fast Track designation from FDA for late-stage antibiotic candidate

New guidelines for radiation therapy after prostatectomy

BIOTRONIK receives FDA approval for ICD/CRT-D series

Clinical data of cabozantinib to be presented at ASCO meeting

New skin cancer drug successfully tested in humans

Study to examine role of arts, humanities in improving mental health and well-being

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Janssen enrolls patients in expanded access program for mantle cell lymphoma

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Breast milk might prevent premature babies from deadly intestinal condition

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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