Therapy News and Research

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Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

AUA and ASTRO release new guideline on adjuvant and salvage radiotherapy after prostatectomy

The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) are pleased to announce the publication of the joint guideline on radiation therapy after prostatectomy for patients with and without evidence of prostate cancer recurrence.

7 May 2013

Implantation of new mechanical heart valve reduces anticoagulation therapy in AVR patients

For more than 40 years, patients under 65 years of age requiring heart valve replacement have had to choose between a mechanical valve that offers life-long durability but requires aggressive warfarin anticoagulation or a biological (cow or pig) valve that will wear out in 10-20 years but does not require anticoagulation.

7 May 2013

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Electroconvulsive therapy (ECT) is the most effective acute treatment for severe major depression. However, even with newer forms of ECT, there remains a significant risk of adverse cognitive effects, particularly memory problems.

7 May 2013

Researchers publish new Canadian guidelines for diagnosis and treatment of fibromyalgia

Physicians from the McGill University Health Centre (MUHC) and the University of Calgary have published a review article in the CMAJ (Canadian Medical Association Journal) to help family doctors diagnose and treat fibromyalgia.

7 May 2013

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

NI Research, the leading publisher of independent research on the neurotherapeutics industry, has released the May issue of NeuroPerspective, which reviews the status and prospects of therapeutics for Parkinson's.

7 May 2013

Prior administration of erythropoietin reduces need for blood transfusions

Anemia increases operative mortality and morbidity in non-cardiac and cardiac surgical procedures. Anemic surgical patients may require more blood transfusions, raising the risk of transfusion-related complications and increasing costs.

7 May 2013

Clinical trial recruits patients with lower back pain to investigate non-surgical treatment

A clinical trial being conducted at the University of British Columbia, sponsored by Active-O, is currently recruiting patients suffering from lower back pain caused by a contained herniated disc to investigate a new, non-surgical treatment.

6 May 2013

Over 90% of medical specialists do not follow ADHD guidelines

A recent study by pediatricians from the Cohen Children's Medical Center of New York examined to what extent pediatric physicians adhere to American Academy of Pediatrics (AAP) clinical guidelines regarding pharmacotherapy in treating young patients with Attention Deficit Hyperactivity Disorder (ADHD).

6 May 2013

Oxygenation targets and outcomes in premature infants

In a randomized trial performed to help resolve the uncertainty about the optimal oxygen saturation therapy in extremely preterm infants, researchers found that targeting saturations of 85 percent to 89 percent compared with 91 percent to 95 percent had no significant effect on the rate of death or disability at 18 months, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the Pediatric Academic Societies annual meeting.

6 May 2013

Oral drops provide a safe and effective alternative for allergy sufferers

Allergy shots are commonly used to treat children with severe environmental allergies and asthma, but under-the-tongue drops may offer yet another beneficial - and stick-free - option for pediatric allergy sufferers, according to a Johns Hopkins Children's Center review of existing scientific evidence.

6 May 2013

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

A new stress test protocol that investigates reducing the use of perfusion imaging in low risk patients undergoing SPECT myocardial perfusion imaging for possible angina symptoms was found to be diagnostically safe, revealed a US retrospective analysis.

6 May 2013

Scioderm gets Breakthrough Therapy designation for SD-101 from FDA for treatment of EB

Scioderm announced its investigational product SD-101 has received Breakthrough Therapy designation by the U.S. Food and Drug Administration for the treatment of patients with inherited Epidermolysis Bullosa.

5 May 2013

U-M launches new center for treating patients with critical conditions

America's emergency, trauma and intensive care teams provide some of the world's most advanced care, bringing patients back from the brink of death on a regular basis.

5 May 2013

Discovery raises hope for severe forms of human epilepsy

Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UC San Francisco researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy.

5 May 2013

Study finds decrease in mortality rates among children initiating ESKD treatment with dialysis

In a study that included more than 20,000 patients, there was a significant decrease in the United States in mortality rates over time among children and adolescents initiating end-stage kidney disease treatment with dialysis between 1990 and 2010, according to a study in the May 8 issue of JAMA.

5 May 2013

Merck's LIPTRUZET tablets get FDA approval for treatment of elevated LDL cholesterol

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LIPTRUZET (ezetimibe and atorvastatin) tablets for the treatment of elevated low-density lipoprotein cholesterol in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet when diet alone is not enough.

4 May 2013

Gene mutation associated with rare sleep disorder also contributes to debilitating migraines

A gene mutation associated with a rare sleep disorder surprisingly also contributes to debilitating migraines, a new discovery that could change the treatment of migraines by allowing development of drugs specifically designed to treat the chronic headaches.

3 May 2013

Newly discovered ‘master regulator’ gene may help develop novel treatment for drug-resistant tumors

Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that this so-called "master regulator" gene may be the key to developing a new treatment for tumors resistant to current drugs.

3 May 2013

New computational method for assessing lung cancer tumors

Moffitt Cancer Center and the University of South Florida have collaborated with researchers in China, the United Kingdom, the Netherlands and Germany to devise a new computational method for assessing lung cancer tumors using CT, PET or MRI diagnostic technologies.

3 May 2013

Therapy News and Research

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

AUA and ASTRO release new guideline on adjuvant and salvage radiotherapy after prostatectomy

Implantation of new mechanical heart valve reduces anticoagulation therapy in AVR patients

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Researchers publish new Canadian guidelines for diagnosis and treatment of fibromyalgia

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

Prior administration of erythropoietin reduces need for blood transfusions

Clinical trial recruits patients with lower back pain to investigate non-surgical treatment

Over 90% of medical specialists do not follow ADHD guidelines

Oxygenation targets and outcomes in premature infants

Oral drops provide a safe and effective alternative for allergy sufferers

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

Scioderm gets Breakthrough Therapy designation for SD-101 from FDA for treatment of EB

U-M launches new center for treating patients with critical conditions

Discovery raises hope for severe forms of human epilepsy

Study finds decrease in mortality rates among children initiating ESKD treatment with dialysis

Merck's LIPTRUZET tablets get FDA approval for treatment of elevated LDL cholesterol

Gene mutation associated with rare sleep disorder also contributes to debilitating migraines

Newly discovered ‘master regulator’ gene may help develop novel treatment for drug-resistant tumors

New computational method for assessing lung cancer tumors

Industry Focus eBook - Cell biology (5th edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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