Therapy News and Research

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Study reveals 3-D motion detection system could help prevent shoulder injuries in baseball pitchers

A new 3-D motion detection system could help identify baseball pitchers who are at risk for shoulder injuries, according to a new study.

24 Apr 2013

Promising development for women with triple-negative breast cancer

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary activities so that it might work on more aggressive breast cancer.

24 Apr 2013

Tissue engineering combined with gene therapy can manage repair of defective articular cartilage

Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells.

24 Apr 2013

Phase IIb Aviator study demonstrates high SVR rates against genotype 1 HCV

Results from "Aviator," AbbVie's phase IIb clinical trial of its investigational direct-acting antivirals for the treatment of hepatitis C virus infection, continue to demonstrate high sustained viral response rates against genotype 1 HCV, across patient types.

24 Apr 2013

Research project to identify mechanisms underlying effects of cancer drug interferon-α

The immune system plays a decisive role in the fight against tumor cells. However, when tumor cells themselves prevent activation of the immune system, the immune system fails to destroy cancer cells.

24 Apr 2013

CytRx reaches agreement with FDA for aldoxorubicin Phase 3 trial for treatment of soft tissue sarcomas

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, announced today that it has reached an agreement with the U.S. Food and Drug Administration under a special protocol assessment for a global pivotal Phase 3 trial with aldoxorubicin as a treatment for patients with soft tissue sarcomas who have relapsed or were refractory following prior treatment with chemotherapy.

24 Apr 2013

Research: DBS may provide therapeutic relief to binge eating

Deep brain stimulation in a precise region of the brain appears to reduce caloric intake and prompt weight loss in obese animal models, according to a new study led by researchers at the University of Pennsylvania.

24 Apr 2013

Methodist Hospital will soon have new brain and pituitary tumor treatment center

Brain and pituitary tumor patients will soon have access to a state-of-the-art facility at The Methodist Hospital, a result of a $10 million dollar commitment from a Houston oil executive.

24 Apr 2013

Investigational treatment for ALS passes early phase clinical trial for safety

An investigational treatment for an inherited form of Lou Gehrig's disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report.

24 Apr 2013

FDA grants orphan-drug designation to XEN402 for treatment of pain associated with EM

Teva Pharmaceutical Industries Ltd. and Xenon Pharmaceuticals Inc. announced today that the US Food and Drug Administration has granted orphan-drug designation to the investigational drug XEN402 being developed for the treatment of pain associated with erythromelalgia.

24 Apr 2013

Data from MK-5172 Phase II study for treatment of HCV genotype 1 infection to be presented at EASL meeting

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced the presentation of the latest interim data from a Phase II, multi-center, randomized, dose-ranging clinical trial evaluating the safety and antiviral activity of MK-5172, for the treatment of chronic hepatitis C virus genotype 1 infection.

24 Apr 2013

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States Food and Drug Administration has approved Sucampo's supplemental new drug application for AMITIZA (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation in adult patients with chronic, non-cancer pain.

24 Apr 2013

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

Janssen R&D Ireland today announced primary efficacy and safety results from two global Phase 3 studies demonstrating that use of the investigational protease inhibitor simeprevir (TMC435) led to sustained virologic response 12 weeks after the end of treatment (SVR12) in 80 and 81 percent, respectively, of treatment-naive genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin.

24 Apr 2013

AACN awards Impact Research Grant to Detroit palliative care expert

The American Association of Critical-Care Nurses recently awarded an AACN Impact Research Grant to Margaret "Meg" Campbell, RN, PhD, FAAN, a nationally known expert in hospital-based palliative care and end-of-life issues.

24 Apr 2013

Some Boston Marathon bomb victims will face insurance coverage limits

ayments for prosthetics, rehabilitation and a range of other treatments may fall outside some insurance limits and could continue long into the future.

24 Apr 2013

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat tissue of obese individuals could provide the same purpose-and could provide the key to a new way for people to lose weight.

24 Apr 2013

Frequent binge drinking in college increases risk of cardiovascular disease later in life

Frequent binge drinking in college can cause more than a hangover. Regularly consuming multiple drinks in a short window of time can cause immediate changes in circulation that increase an otherwise healthy young adult's risk of developing cardiovascular disease later in life, according to research published online today in the Journal of the American College of Cardiology.

24 Apr 2013

McGraw-Hill publishes preeminent textbook for pulmonary physiology in Lange Physiology Series

The 8th Edition of PULMONARY PHYSIOLOGY by Dr. Michael G. Levitzky, Professor of Physiology, Anesthesiology, and Cardiopulmonary Science at LSU Health Sciences Center New Orleans, was published this month by McGraw-Hill in its Lange Physiology Series.

24 Apr 2013

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Rheumatoid arthritis (RA) is an autoimmune disorder that can cause debilitating joint damage. In cases of RA, the immune system attacks the body’s own tissues, especially the membranes that line the joints. As a result, fluid builds up in the joints, causing pain and systemic inflammation, leading to joint destruction if untreated.

From Quest Diagnostics 23 Apr 2013

Study: Stressful situations at work can have negative impact on cardiovascular system and metabolism

Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, which can trigger cardiovascular diseases, amongst others.

23 Apr 2013

Therapy News and Research

Study reveals 3-D motion detection system could help prevent shoulder injuries in baseball pitchers

Promising development for women with triple-negative breast cancer

Tissue engineering combined with gene therapy can manage repair of defective articular cartilage

Phase IIb Aviator study demonstrates high SVR rates against genotype 1 HCV

Research project to identify mechanisms underlying effects of cancer drug interferon-α

CytRx reaches agreement with FDA for aldoxorubicin Phase 3 trial for treatment of soft tissue sarcomas

Research: DBS may provide therapeutic relief to binge eating

Methodist Hospital will soon have new brain and pituitary tumor treatment center

Investigational treatment for ALS passes early phase clinical trial for safety

FDA grants orphan-drug designation to XEN402 for treatment of pain associated with EM

Data from MK-5172 Phase II study for treatment of HCV genotype 1 infection to be presented at EASL meeting

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

AACN awards Impact Research Grant to Detroit palliative care expert

Some Boston Marathon bomb victims will face insurance coverage limits

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Frequent binge drinking in college increases risk of cardiovascular disease later in life

McGraw-Hill publishes preeminent textbook for pulmonary physiology in Lange Physiology Series

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Study: Stressful situations at work can have negative impact on cardiovascular system and metabolism

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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