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Study shows intraventricular chemotherapy increases overall survival in LMC patients

Lung cancer is one of the most common primary cancers that cause leptomeningeal carcinomatosis (LMC), when cancer spreads to the membranes surrounding the spinal cord and brain. Cases of LMC have increased because of the improved survival of lung cancer patients with the help of new advances in treatment.

23 Apr 2013

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced non-small cell lung cancer (NSCLC) harboring specific HER2 protein mutations.

23 Apr 2013

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the main cause of cancer-related deaths.

23 Apr 2013

Animal models of Huntington's disease allow better insights into disease's genetics

Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology.

23 Apr 2013

BTS launches belt to prevent lower back pain problems

FIK, Tecnalia and BTS launch a belt to prevent lower back pain problems and provide rehabilitation at home and at work. The Lumbia device can be used for patient´s assessment, and for therapy during postural re-education.

23 Apr 2013

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA.

23 Apr 2013

Study suggests specific form of vitamin E supplement improves function of blood vessels

Taking a specific form of a vitamin E supplement can accelerate the health benefits that occur when people quit smoking, new research suggests.

23 Apr 2013

Researchers explore new technique to determine the activity of different calcium channels in cancer cells

Two Wayne State University researchers are working on a technique that could lead to easier, faster identification of cancer tumors that can be effectively treated by calcium channel-based therapies.

23 Apr 2013

Clinical data on simeprevir for treatment of hepatitis C patients to be presented at EASL meeting

Medivir AB today announces that data will be presented on the investigational protease inhibitor simeprevir (TMC435) for the treatment of genotype 1 hepatitis C patients.

23 Apr 2013

First Edition: April 23, 2013

Today's headlines include reports about immigrant patients' health care as well as the coverage limits that some victims of the Boston Marathon bombings might face.

23 Apr 2013

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Gilead Sciences, Inc. today announced that detailed results from four Phase 3 clinical trials (NEUTRINO, FISSION, POSITRON and FUSION) evaluating sofosbuvir, the company's investigational once-daily nucleotide NS5B inhibitor for the treatment of chronic hepatitis C virus infection, will be presented this week in oral sessions at the 48th Annual Meeting of the European Association for the Study of the Liver in Amsterdam, The Netherlands.

23 Apr 2013

Oncology nurses explore how to better combat patient fatigue

They are key members of the healthcare team who face ongoing challenges on how best to provide optimum care to patients affected by cancer. Oncology nurses at The Cancer Institute of New Jersey continually strive to improve patient care and have recently explored how to better combat patient fatigue, the importance of documenting sleep-wake disturbances and the development of a toolkit to help patients better follow their oral treatment schedule during clinical trials.

23 Apr 2013

TSRI scientists find way to directly turn bone marrow stem cells into brain cells

In a serendipitous discovery, scientists at The Scripps Research Institute have found a way to turn bone marrow stem cells directly into brain cells.

23 Apr 2013

ViroPharma announces results of VP20621 Phase 2 study for preventing recurrent CDI

ViroPharma Incorporated, an international biopharmaceutical company committed to developing and commercializing innovative products that address unmet medical needs and rare diseases, today announced the results of a Phase 2 study of VP20621 (non-toxigenic Clostridium difficile; NTCD) a novel treatment approach for preventing recurrent C. difficile infections.

23 Apr 2013

ARCA biopharma, Medtronic to study effectiveness of Gencaro for prevention of atrial fibrillation

ARCA biopharma, Inc., a biopharmaceutical company developing genetically-targeted therapies for cardiovascular diseases, today announced that it has entered into an agreement with Medtronic, Inc., a leader in medical technologies to improve the treatment of chronic diseases, including cardiac rhythm disorders, to collaborate on ARCA's proposed clinical trial, known as GENETIC-AF, of its lead developmental drug Gencaro (bucindolol hydrochloride).

From Medtronic 23 Apr 2013

State roundup: Calif. lawmakers push for health plan for immigrants in U.S. illegally

A selection of health policy stories from Massachusetts, California, Michigan, Texas, the District of Columbia, Pennsylvania, South Carolina and Tennessee.

23 Apr 2013

William Meehan wins AMSSM Foundation-ACSM Foundation Clinical Research Grant to study brain injury

William Meehan, MD, is the first recipient of the AMSSM Foundation-ACSM Foundation Clinical Research Grant for his research titled "A Randomized, Double-Blind, Placebo-Controlled Trial of Transcranial Light Emitting Diode Therapy for the Treatment of Chronic Concussive Brain Injury."

23 Apr 2013

Cystic Fibrosis Foundation issues statement on Phase 2 clinical trial of Kalydeco, VX-661

The Cystic Fibrosis Foundation issued the following statement in response to an announcement by Vertex Pharmaceuticals Inc. regarding promising results from a Phase 2 clinical trial of its cystic fibrosis drug Kalydeco in combination with another potential CF therapy, VX-661.

23 Apr 2013

NKI-AVL joins research consortium to develop MRI-guided radiation therapy system for cancer care

Elekta and Royal Philips Electronics announced today that The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital has signed an agreement to join a research group to advance the development of ground-breaking image-guided treatment technology for cancer care.

From Elekta 23 Apr 2013

Enrollment for Pharmacyclics' Phase III study using ibrutinib in CLL patients completed

Pharmacyclics, Inc. announced today that the enrollment target of 350 patients for its Phase III study using ibrutinib monotherapy versus ofatumumab in patients with relapsed or refractory chronic lymphocytic leukemia / small lymphocytic lymphoma, (RESONATE) was achieved on April 3, 2013.

23 Apr 2013

Therapy News and Research

Study shows intraventricular chemotherapy increases overall survival in LMC patients

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Animal models of Huntington's disease allow better insights into disease's genetics

BTS launches belt to prevent lower back pain problems

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Study suggests specific form of vitamin E supplement improves function of blood vessels

Researchers explore new technique to determine the activity of different calcium channels in cancer cells

Clinical data on simeprevir for treatment of hepatitis C patients to be presented at EASL meeting

First Edition: April 23, 2013

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Oncology nurses explore how to better combat patient fatigue

TSRI scientists find way to directly turn bone marrow stem cells into brain cells

ViroPharma announces results of VP20621 Phase 2 study for preventing recurrent CDI

ARCA biopharma, Medtronic to study effectiveness of Gencaro for prevention of atrial fibrillation

State roundup: Calif. lawmakers push for health plan for immigrants in U.S. illegally

William Meehan wins AMSSM Foundation-ACSM Foundation Clinical Research Grant to study brain injury

Cystic Fibrosis Foundation issues statement on Phase 2 clinical trial of Kalydeco, VX-661

NKI-AVL joins research consortium to develop MRI-guided radiation therapy system for cancer care

Enrollment for Pharmacyclics' Phase III study using ibrutinib in CLL patients completed

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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