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Combination of INF and glatiramer acetate does not reduce MS progression

A recent clinical trial found that interferonβ-1a (INF) and glatiramer acetate (GA), two of the most commonly prescribed drugs for multiple sclerosis (MS), provide no additional clinical benefit when taken together.

12 Mar 2013

$Sildenafil does not help heart failure patients with preserved ejection fraction$

Sildenafil does not help heart failure patients with preserved ejection fraction

A commonly used erectile dysfunction drug, sildenafil, doesn't help patients who have heart failure with preserved ejection fraction, a condition in which the heart's lower chambers are stiff and cannot relax and fill fully between beats.

12 Mar 2013

UniStem Day 2013 to take place on Mar. 15

This year, six Spanish universities participate in UniStem Day 2013, an event that takes place next Friday, 15th March. It is the first time that the event is carried out simultaneously in several European countries.

12 Mar 2013

New Sapien XT aortic valve reduces rate of death and strokes

The new Sapien XT aortic valve showed a non-significantly lower rate of death and strokes at 30 days than the original model, and both valves demonstrated notably better short-term outcomes than seen with the Sapien system in PARTNER I, according to the first results from the PARTNER II study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Study: No increase in mortality with well-controlled HIV

For HIV-infected patients whose disease is well-controlled by modern treatment, the risk of death is not significantly higher than in the general population, according to a study published in AIDS, official journal of the International AIDS Society. AIDS is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

12 Mar 2013

Combining weight loss therapy and CPAP can help reduce blood pressure in OSA patients

Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with high blood pressure. The effects of weight loss and continuous positive airway pressure (CPAP), the standard therapy for OSA, on blood pressure have been previously studied individually, but the incremental benefit of combination therapy (weight loss and CPAP therapy) over either therapy alone in obese patients with OSA has been unknown.

12 Mar 2013

Measuring avoidance could predict children's development of anxiety

Children who avoid situations they find scary are likely to have anxiety a Mayo Clinic study of more than 800 children ages 7 to 18 found. The study published this month in Behavior Therapy presents a new method of measuring avoidance behavior in young children.

12 Mar 2013

On and off-pump coronary artery bypass surgery equally safe, effective for older patients

Older patients did as well after undergoing coronary bypass surgery off-pump as they did with the more costly "on-pump" procedure using a heart-lung machine to circulate blood and oxygen through the body during surgery, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Researchers uncover clear genetic link between fat and bone mass

When it comes to body shape, diet and exercise can only take us so far. Our body shape and geometry are largely determined by genetic factors. Genetics also have an impact on our body composition - including soft fat tissue and hard bone tissue - and can lead to excess fat or osteoporosis.

12 Mar 2013

Scientist awarded $1.2M grant to develop therapy to reduce premature births

A scientist at Case Western Reserve University School of Medicine has been awarded a $1.2 million grant to develop a therapy to reduce the prevalence of premature births, which today affect more than 15 million newborns worldwide each year.

11 Mar 2013

Scientists develop new method for replacing missing teeth

Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells.

11 Mar 2013

Genetic mutation that alters PIEZO1 ion channel in RBCs contributes to familial xerocytosis

A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the Proceedings of the National Academy of Sciences by University at Buffalo scientists and colleagues.

11 Mar 2013

IP chemotherapy increases survival in patients with advanced ovarian cancer

Patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV) chemotherapy, according to a study that analyzed long-term follow-up from two landmark Gynecologic Oncology Group (GOG) trials comprising 876 patients.

11 Mar 2013

Adrenocorticotropic hormone may help treat people with multiple sclerosis

A new study suggests that treatment with adrenocorticotropic hormone (ACTH) may be helpful for people whose multiple sclerosis (MS) is not well-controlled through their regular treatment. The study was released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

11 Mar 2013

Abbott announces data from MitraClip system study on mitral regurgitation

Abbott today announced data from the EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) High Surgical Risk cohort evaluating the company's first-in-class catheter-based MitraClip System for the treatment of mitral regurgitation (MR).

11 Mar 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013