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Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Ceregene, Inc. today announced the top-line data from its double-blind, randomized, controlled Phase 2b clinical study of CERE-120 (AAV-neurturin), a gene therapy product designed to deliver the neurotrophic factor neurturin, for Parkinson's disease.

20 Apr 2013

Penn Medicine gene therapy study receives Distinguished Clinical Research Achievement Award

A gene therapy study focused on finding a cure for a rare congenital blinding disease has been recognized as one of the ten most outstanding clinical research projects of the year by the Clinical Research Forum.

20 Apr 2013

Study identifies seven new genetic regions associated with pulmonary fibrosis

A new genome-wide association study of more than 6,000 people has identified seven new genetic regions associated with pulmonary fibrosis. In findings published online in Nature Genetics on April 14, 2013, researchers at National Jewish Health, the University of Colorado and several other institutions found a number of genes associated with host defense, cell-cell adhesion and DNA repair, which provide clues to possible mechanisms underlying this currently untreatable disease.

20 Apr 2013

Civitas Therapeutics reports positive results from Phase 2 study of CVT-301 for Parkinson's disease

Civitas Therapeutics, Inc., a privately-held pharmaceutical company developing transformative therapeutics using the ARCUS respiratory delivery platform, today announced positive topline results from a Phase 2 clinical trial of CVT-301, an inhaled formulation of levodopa (L-dopa).

20 Apr 2013

Highlights: Local Kan. program seeks to prevent readmissions with food deliveries; Conn. officials want stricter limit on insurer markup

A selection of health policy stories from Kansas, Connecticut, Oregon, the District of Columbia, Texas, Florida, Minnesota and California.

20 Apr 2013

Research shows early access to cognitive behavioural therapy can reduce risk of psychosis

Young people seeking help who are at high risk of developing psychosis could significantly reduce their chances of going on to develop a full-blown psychotic illness by getting early access to cognitive behavioural therapy, new research shows.

From The University of Manchester 19 Apr 2013

Long winter months impact tamoxifen treatment for breast cancer

For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer.

19 Apr 2013

Combination therapies may advance treatment for anaplastic thyroid cancer

A combination of therapies may prove to be a promising advance for the treatment of anaplastic thyroid cancer based on results of a phase I clinical trial, say researchers at Mayo Clinic in Florida.

19 Apr 2013

First Edition: April 19, 2013

Today's headlines include reports about a new plan by the Bipartisan Policy Center to reduce health spending released.

19 Apr 2013

PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

Pharmaco-Kinesis Corporation, developer of a pre-commercialized smart implantable pump for localized cancer-fighting drug delivery, today announced its first commercialized offering, the first-generation Nano-Impedance Biosensor.

19 Apr 2013

ASTRO white paper recommends 10 fundamental elements of IGRT safety in clinical programs

The American Society for Radiation Oncology has issued a new white paper, "Assuring Safety and Quality in Image Guided Delivery of Radiation Therapy," that recommends best practices to improve the safety and effectiveness of image guided radiation therapy, according to the manuscript published as an article in press online in Practical Radiation Oncology, the official clinical practice journal of ASTRO.

19 Apr 2013

SironRX completes enrollment in Cohort 1 to study JVS-100 for wound healing, scar prevention

SironRX Therapeutics Inc., a privately-held, clinical-stage biotechnology company developing novel regenerative therapies to prevent scarring and promote dermal wound repair, is pleased to report that it has completed enrollment of patients in Cohort 1 of its placebo-controlled, randomized, dose escalation double-blind clinical study evaluating the safety and efficacy of JVS-100 to reduce scar formation and improve wound healing in patients receiving surgical sternotomy incisions.

19 Apr 2013

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

ADial Pharmaceuticals, LLC, announced today that the U.S. Food and Drug Administration has agreed to allow ADial to move forward with its plan to initiate Phase III trials of AD04 as a treatment for alcohol use disorder in certain targeted genotypes population only.

19 Apr 2013

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

An Indiana University School of Medicine breast cancer surgeon is pursuing research that will utilize glass, gold, nanotechnology and Greek mythology hoping to vanquish breast cancer that has metastasized to the brain.

19 Apr 2013

Ribavirin, interferon-alpha 2b inhibit virus replication in cell culture, NIH study finds

National Institutes of Health scientists studying an emerging coronavirus have found that a combination of two licensed antiviral drugs, ribavirin and interferon-alpha 2b, can stop the virus from replicating in laboratory-grown cells.

19 Apr 2013

Patient enrollment underway in Phase III trial program to evaluate amikacin inhalation solution

Bayer HealthCare Pharmaceuticals Inc. announced today that patient enrollment is underway in its global Phase III trial program to evaluate the efficacy and safety of adjunctive aerosolized BAY41-6551 versus aerosolized placebo in the treatment of intubated and mechanically ventilated patients with Gram-negative pneumonia receiving standard of care intravenous antibiotics.

19 Apr 2013

Researchers propose strategies for improving the anti-cancer effects of interferon

Interferons have antitumor activity and have been used to treat a variety of malignancies, including colorectal and ovarian cancers.

18 Apr 2013

New assays are effective in managing patients with influenza virus infection

Over 40,000 people die each year in the United States from influenza-related diseases. In patients whose immune systems are compromised, antiviral therapy may be life-saving, but it needs to be initiated quickly. It is therefore crucial to diagnose and type the influenza rapidly.

18 Apr 2013

New invasive tumor ablation technique provides hope for liver cancer patients

A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows.

18 Apr 2013

CT imaging and serum LDH can predict survival in patients with metastatic melanoma

Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastatic melanoma being treated with anti-angiogenic therapy.

18 Apr 2013

Therapy News and Research

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Penn Medicine gene therapy study receives Distinguished Clinical Research Achievement Award

Study identifies seven new genetic regions associated with pulmonary fibrosis

Civitas Therapeutics reports positive results from Phase 2 study of CVT-301 for Parkinson's disease

Highlights: Local Kan. program seeks to prevent readmissions with food deliveries; Conn. officials want stricter limit on insurer markup

Research shows early access to cognitive behavioural therapy can reduce risk of psychosis

Long winter months impact tamoxifen treatment for breast cancer

Combination therapies may advance treatment for anaplastic thyroid cancer

First Edition: April 19, 2013

PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

ASTRO white paper recommends 10 fundamental elements of IGRT safety in clinical programs

SironRX completes enrollment in Cohort 1 to study JVS-100 for wound healing, scar prevention

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

Ribavirin, interferon-alpha 2b inhibit virus replication in cell culture, NIH study finds

Patient enrollment underway in Phase III trial program to evaluate amikacin inhalation solution

Researchers propose strategies for improving the anti-cancer effects of interferon

New assays are effective in managing patients with influenza virus infection

New invasive tumor ablation technique provides hope for liver cancer patients

CT imaging and serum LDH can predict survival in patients with metastatic melanoma

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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