Central Nervous System News and Research

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Top-line results from Neuraltus’ NP001 Phase 2 study on amyotrophic lateral sclerosis

Neuraltus Pharmaceuticals, a private biopharmaceutical company developing novel therapies for rare neurological disorders, announced today top-line results from the Company's Phase 2 clinical study of NP001 in patients with Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's disease).

30 Oct 2012

Complix to accelerate development of CPABs against intracellular disease targets

Complix announces that it has been awarded a €1.9 million grant (approximately USD$2.4 million) from the Flanders government through IWT (Agency for Innovation by Science and Technology in Flanders).

30 Oct 2012

Lessons can be learnt from US fungal meningitis outbreak

As the current outbreak of fungal meningitis caused by contaminated methylprednisolone acetate injections continues to spread across the USA, past experience suggests that lessons can be learnt, says a US researcher.

24 Oct 2012

Metabolic pathway for insulin effects of sleep identified

Sleep deprivation reduces insulin sensitivity in human fat cells, which could, over time, lead to metabolic disorders such as diabetes, researchers report.

23 Oct 2012

Pfizer announces intention to acquire NextWave

Pfizer Inc. today announced its intention to acquire NextWave Pharmaceuticals, a privately held, specialty pharmaceutical company focused on the development and commercialization of unique products for the treatment of attention deficit/hyperactivity disorder (ADHD) and related central nervous system (CNS) disorders.

23 Oct 2012

Intensive glycemic control does not reduce mortality in neurocritical care patients

A new study in BioMed Central's open access journal Critical Care suggests that intensive glycemic control does not reduce mortality in neurocritical care patients and could, in fact, lead to more neurological damage. Complicating the picture, poor glucose control also leads to worse recovery and should be avoided.

22 Oct 2012

Research director at Kessler Foundation awarded NIH grant to study effects of chemotherapy on brain

Guang Yue, PhD, director of Human Performance and Engineering Research at Kessler Foundation, has been awarded a grant by the National Institutes of Health to study the effects of chemotherapy on brain structure, neurophysiology, and psychomotor behavior.

20 Oct 2012

Animal research shows promise in treating AD, brain damage and heart problems resulting from SCIs

New animal studies provide additional support for investigating stem cell treatments for Parkinson's disease, head trauma, and dangerous heart problems that accompany spinal cord injury, according to research findings released today.

16 Oct 2012

Scientists take first steps to create neural-like stem cells from muscle tissue

Scientists at Wake Forest Baptist Medical Center have taken the first steps to create neural-like stem cells from muscle tissue in animals.

15 Oct 2012

Genzyme announces key data from AUBAGIO Phase III trial on multiple sclerosis

Genzyme, a Sanofi company announced today that key data from the TOWER trial were presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).

15 Oct 2012

Two CUMC studies provide new insights into spinal muscular atrophy

A study by scientists from the Motor Neuron Center at Columbia University Medical Center (CUMC) suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought.

12 Oct 2012

Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

Sun protection: an interview with Jane Hanrahan

UV radiation is a form of energy being transmitted. Sunlight is main source of UV radiation, although manmade sources also exist, such as the lamps used in sunbeds. At the earth’s surface sunlight consists of approximately 2 percent UV light, 47 percent visible light and 51 percent IR light.

11 Oct 2012

Meningitis outbreak fuels calls for more oversight

According to the Centers for Disease Control and Prevention, eight people have died and 105 people in nine states have been sickened by a type of fungal meningitis they were exposed to when they received tainted spinal steroid injections.

10 Oct 2012

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

10 Oct 2012

Anesthetic-loaded liposomes can delay onset of neuropathic pain

Using tiny spheres filled with an anesthetic derived from a shellfish toxin, researchers at Boston Children's Hospital and the Massachusetts Institute of Technology have developed a way to delay the rise of neuropathic pain, a chronic form of pain that arises from flawed signals transmitted by damaged nerves.

10 Oct 2012

Mayo researchers discover new therapy for patients with neuromyelitis optica

Mayo Clinic researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating central nervous system disorder that is often misdiagnosed as multiple sclerosis (MS).

10 Oct 2012

First Edition: October 9, 2012

Today's headlines include reports about how a new poll indicates GOP presidential hopeful Mitt Romney gained a significant bounce from last week's debate performance.

9 Oct 2012

Scientists discover how protein deficiency may be linked to frontotemporal dementia

Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)-a form of early-onset dementia that is similar to Alzheimer's disease. These results lay the foundation for therapies that one day may benefit those who suffer from this and related diseases that wreak havoc on the brain.

9 Oct 2012

ImaginAb enters into neurodegeneration research collaboration agreement with Lundbeck

ImaginAb, Inc., a clinical-stage company developing in vivo molecular imaging agents based on antibody fragment technology, today announced that it has entered into a collaboration and commercialization agreement with H. Lundbeck A/S.

8 Oct 2012

Central Nervous System News and Research

Top-line results from Neuraltus’ NP001 Phase 2 study on amyotrophic lateral sclerosis

Complix to accelerate development of CPABs against intracellular disease targets

Lessons can be learnt from US fungal meningitis outbreak

Metabolic pathway for insulin effects of sleep identified

Pfizer announces intention to acquire NextWave

Intensive glycemic control does not reduce mortality in neurocritical care patients

Research director at Kessler Foundation awarded NIH grant to study effects of chemotherapy on brain

Animal research shows promise in treating AD, brain damage and heart problems resulting from SCIs

Scientists take first steps to create neural-like stem cells from muscle tissue

Genzyme announces key data from AUBAGIO Phase III trial on multiple sclerosis

Two CUMC studies provide new insights into spinal muscular atrophy

Investigators provide overview of role of dopamine in modulating the immune system

Sun protection: an interview with Jane Hanrahan

Meningitis outbreak fuels calls for more oversight

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Anesthetic-loaded liposomes can delay onset of neuropathic pain

Mayo researchers discover new therapy for patients with neuromyelitis optica

First Edition: October 9, 2012

Scientists discover how protein deficiency may be linked to frontotemporal dementia

ImaginAb enters into neurodegeneration research collaboration agreement with Lundbeck

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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