Therapy News and Research

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Study: Shock wave-facilitated cell therapy improves outcomes in patients with chronic heart failure

Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement in left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each contraction) after 4 months in patients with chronic postinfarction heart failure, according to a study in the April 17 issue of JAMA.

18 Apr 2013

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

ARMGO Pharma and the Muscular Dystrophy Association today announced that $1 Million has been awarded for preclinical work in support of an Investigational New Drug application with the U.S. Food and Drug Administration for ARM210, a novel, orally available, small-molecule Rycal drug that has potential as a treatment for Duchenne muscular dystrophy.

18 Apr 2013

MD Anderson Cancer Center buys two Elekta Versa HD linear accelerators

The University of Texas MD Anderson Cancer Center (Houston, Texas) has purchased two Elekta Versa HD™ linear accelerators. The radiation therapy system, which recently received 510(k) clearance from the U.S. Food and Drug Administration, features the versatility to deliver high-volume conventional techniques, in addition to the most advanced linear-accelerator treatments that require the greatest targeting precision.

From Elekta 18 Apr 2013

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

Scientists from academic institutions reported at the 2013 annual American Association for Cancer Research meeting, results from preclinical studies which showed that certain bladder cancers and mesotheliomas have metabolic changes and are more likely to respond to treatment with ADI-PEG 20 (pegylated arginine deiminase) if they are deficient in the enzyme, argininosuccinate synthetase.

18 Apr 2013

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists have overcome a major impediment to the development of effective stem cell therapies by studying mice that lack CD47, a protein found on the surface of both healthy and cancer cells.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

Phase III clinical trial data of Milprosa vaginal ring presented at PCRS annual meeting

Teva Pharmaceutical Industries Ltd. today presented data from a sub-analysis of a Phase III clinical trial of Milprosa (progesterone) vaginal ring, an investigational, once-weekly therapy for luteal phase support in women undergoing in vitro fertilization.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins.

18 Apr 2013

Researchers find potential new genetic chemotherapy approach for cancer treatment

Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment that could significantly reduce side effects and the development of treatment resistance compared with traditional chemotherapy.

18 Apr 2013

Mindfulness-based cognitive therapies have significant benefits for veterans with PTSD

Mindfulness exercises that include meditation, stretching, and acceptance of thoughts and emotions might help veterans with combat-related post-traumatic stress disorder find relief from their symptoms.

18 Apr 2013

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated.

18 Apr 2013

Primary mediastinal B-cell lymphoma has better outcome with more dose-intense regimens

Patients with a type of cancer known as primary mediastinal B-cell lymphoma who received infusions of chemotherapy, but who did not have radiation therapy to an area of the thorax known as the mediastinum, had excellent outcomes, according to clinical trial results.

18 Apr 2013

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

RNAi-based therapeutics company Benitec Biopharma Limited today announced that the company's wholly owned US subsidiary, Tacere Therapeutics Inc., has submitted an application to the US National Institutes of Health's Recombinant DNA Advisory Committee.

18 Apr 2013

EKG could predict cardiovascular illness

A common test that records the heart's electrical activity could predict potentially serious cardiovascular illness, according to a UC San Francisco-led study.

17 Apr 2013

Study confirms crizotinib drug reduces testosterone levels

A previous study by the University of Colorado Cancer Center reported the common side effect of low testosterone in men treated with the recently approved lung cancer agent, crizotinib.

17 Apr 2013

Study shows TOLLIP gene variant is linked to increased mortality risk in IPF patients

A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that was linked to an increase in the risk of death.

17 Apr 2013

Antiretroviral therapy does not affect resting energy expenditure in HIV-infected women

Studies have shown that about 10 percent of men infected with human immunodeficiency virus have an elevated resting energy expenditure.

17 Apr 2013

Preclinical data on anti-cancer activity of BI-505 published online in Cancer Cell

BioInvent International AB, a biotech company developing novel antibody therapeutics for treatment of cancer, today announced that the April 15, 2013 online issue of the highly prestigious cancer research journal Cancer Cell features a data publication demonstrating potent anti-cancer activity of BI-505 in multiple preclinical myeloma tumor models.

17 Apr 2013

Researchers report progress on non-invasive method to assess kidney function

Researchers may have found a way to block kidney-destroying inflammation and help damaged kidney cells recover.

17 Apr 2013

Therapy News and Research

Study: Shock wave-facilitated cell therapy improves outcomes in patients with chronic heart failure

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

MD Anderson Cancer Center buys two Elekta Versa HD linear accelerators

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

NCI researchers overcome major impediment to development of effective stem cell therapies

Findings hold promise for development of therapies to fight different viral infections

Phase III clinical trial data of Milprosa vaginal ring presented at PCRS annual meeting

UTMB researchers identify protein that can interfere with the brain's response to leptin

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

Researchers find potential new genetic chemotherapy approach for cancer treatment

Mindfulness-based cognitive therapies have significant benefits for veterans with PTSD

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Primary mediastinal B-cell lymphoma has better outcome with more dose-intense regimens

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

EKG could predict cardiovascular illness

Study confirms crizotinib drug reduces testosterone levels

Study shows TOLLIP gene variant is linked to increased mortality risk in IPF patients

Antiretroviral therapy does not affect resting energy expenditure in HIV-infected women

Preclinical data on anti-cancer activity of BI-505 published online in Cancer Cell

Researchers report progress on non-invasive method to assess kidney function

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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