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New peptide molecule offers hope for emphysema

Emphysema is a progressive, debilitating lung disease in which the lung's breathing sacs, or alveoli, enlarge, get thinner, and eventually are destroyed as the cells die off. It can be fatal, and there is currently no cure.

4 Aug 2020

Researchers initiate multiple studies to identify coronavirus-related heart problems

COVID-19 is shown to impact the heart and, in some cases, have long-lasting cardiac effects. To discover the extent to which COVID-19 affects the heart, cardiologists and researchers with the University of Miami Miller School of Medicine have begun multiple studies.

4 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

ALKBH5 enzyme shows promising target for cancer immunotherapy

Cancer immunotherapy - a treatment that better enables a patient's own immune system to attack tumors - has shown great potential against some cancers. Yet immunotherapy doesn't work against all tumor types, and many patients who initially respond later develop resistance and relapse.

4 Aug 2020

Targeting LDL cholesterol to reduce heart disease risk now questioned

For many years, health experts have warned that high levels of bad cholesterol or low-density lipoprotein (LDL) are critical drivers for the development of cardiovascular disease. Now, a new study claims that decades of research have failed to show benefit of targeting the bad cholesterol to reduce the risk of cardiovascular disease.

4 Aug 2020

Low-income communities lack access to ICU beds

A new Penn Medicine study sheds light on yet another reason why the coronavirus pandemic is disproportionately killing the poor: Residents in low-income neighborhoods lack access to intensive care unit (ICU) beds.

3 Aug 2020

Study identifies possible therapeutic treatment for COVID-19

Yunjeong Kim and Kyeong-Ok "KC" Chang, virologists in the College of Veterinary Medicine at Kansas State University, have published a study showing a possible therapeutic treatment for COVID-19.

3 Aug 2020

Artificial intelligence can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

3 Aug 2020

Study reveals impact of TP53 gene mutations on MDS severity

Considered the "guardian of the genome," TP53 is the most commonly mutated gene in cancer. TP53's normal function is to detect DNA damage and prevent cells from passing this damage on to daughter cells.

3 Aug 2020

Penn researchers identify genetic driver of Charcot-Marie-Tooth disease

Inherited mutations in a gene that keeps nerve cells intact was shown, for the first time, to be a driver of a neuropathy known as Charcot-Marie-Tooth (CMT) disease.

3 Aug 2020

Research explains recognized sex differences in COVID-19 outcomes

The COVID-19 pandemic has notably taken a more significant toll on men compared to women, in terms of both disease severity and death. Now, a new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in August 2020 confirms the increased risk that males have for death following COVID-19 while also highlighting worse outcomes in women with coronary artery disease, obesity, and hypoxia compared to men.

3 Aug 2020

Study uncovers how schistosome worms trick the host's immune system

Researchers uncovered in a new study how schistosomes, parasitic flatworms that infect more than 200 million people in the tropics, trick the host's immune system and continue producing eggs for decades.

3 Aug 2020

Asthma drugs improve performance in healthy non-asthmatic subjects

Popular asthma control drugs β2-agonists such as Albuterol, Formoterol, Terbutaline, etc. that are used as inhalers by millions of asthmatics around the world could have power and stamina enhancing properties in sportspersons, finds a new study.

3 Aug 2020

Snapchat found to be an effective tool to teach residents emergency radiology

A pilot study conducted by a team of LSU Health New Orleans School of Medicine faculty has found that Snapchat is an effective tool to teach residents emergency radiology.

3 Aug 2020

Study shows high SARS-CoV-2 seroprevalence, but low death rate in Malawi's health care workers

A study by researchers from Malawi and United Kingdom reveals a significant discrepancy between predicted coronavirus disease (COVID-19) mortality in the observed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence rates in health care workers and reported deaths in urban Malawi in southeastern Africa, indicating early exposure, but a slow progression of the outbreak. Their findings are currently available on the medRxiv preprint server.

3 Aug 2020