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Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

Researchers improve NanoVelcro device to better grab cancer cells as blood passes by them

Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients' tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.

26 Feb 2013

External qigong therapy can help control cocaine craving early in recovery

Cocaine is one of the most addictive drugs of abuse. Few effective treatments are available to help control cravings and withdrawal symptoms among individuals undergoing therapy to overcome cocaine abuse.

26 Feb 2013

Thermo Fisher Scientific launches Brilliance GBS Agar

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of Brilliance GBS Agar for the testing of Group B streptococci (GBS) during pregnancy.

From Thermo Fisher Scientific Inc. 26 Feb 2013

BIOTRONIK receives FDA approval for Lumax 740 DX System

BIOTRONIK, a leading manufacturer of cardiovascular medical technology, announced the Food and Drug Administration (FDA) has granted final approval for the BIOTRONIK Lumax 740 DX System.

26 Feb 2013

Adynxx initiates AYX1 Phase 2 study to prevent post-surgical pain

Adynxx, a clinical-stage pharmaceutical company developing a first-in-class platform of therapeutics to address pain at its molecular roots, announced today that the first patient was dosed in a Phase 2 study of its lead investigational drug candidate for the prevention of post-surgical pain, AYX1.

26 Feb 2013

Bayer receives FDA approval for Stivarga to treat advanced gastrointestinal stromal tumors

The U.S. Food and Drug Administration today expanded the approved use of Stivarga (regorafenib) to treat patients with advanced gastrointestinal stromal tumors (GIST) that cannot be surgically removed and no longer respond to other FDA-approved treatments for this disease.

26 Feb 2013

Kindred Healthcare fourth quarter consolidated revenues increase 2% to $1.55 billion

Kindred Healthcare, Inc. today announced its operating results for the fourth quarter and year ended December 31, 2012.

25 Feb 2013

Better representation of elderly patients in phase III trials can improve evidence-based treatment

The median age of patients diagnosed with advanced non-small-cell lung cancer (NSCLC) has steadily increased over the recent years and is presently 70 years. Despite this, the elderly are significantly underrepresented in clinical trials.

25 Feb 2013

Screening of children with LUT dysfunction needs refining

Physicians should include screening for psychosocial comorbidities and obesity when evaluating children with lower urinary tract dysfunction, say researchers.

25 Feb 2013

WOEST supports clopidogrel only in PCI patients on anticoagulation

Publication of the WOEST trial results reaffirm the study’s major finding that antiplatelet therapy with clopidogrel alone is preferable to the use of both aspirin and clopidogrel in patients undergoing percutaneous coronary intervention who are receiving oral anticoagulant therapy.

25 Feb 2013

CT angiography uncovers cardiovascular disease risk

Computed tomography angiography can warn of the likelihood for major adverse cardiovascular events in patients suspected of having coronary artery disease in the absence of medically modifiable risk factors, research shows.

25 Feb 2013

Substance use increased in teens with ADHD

Adolescents with attention deficit hyperactivity disorder have significantly higher rates of substance abuse and cigarette use than their peers without the condition, US research shows.

25 Feb 2013

Kaposi’s sarcoma risk factors revealed

Scientists have uncovered an intriguing relationship between the risk for Kaposi’s sarcoma, smoking, and the use of highly active antiretroviral therapy.

25 Feb 2013

Next generation deep brain stimulation (DBS) therapy to be developed by Sapiens

Sapiens Steering Brain Stimulation B.V. (Sapiens), an emerging medical technology company developing brain stimulation products, today announced that it has raised €7.5 m from the Dutch investment group INKEF Capital, in a further extension of their Series A financing round. The proceeds will be used for the development of its Steering Brain Stimulation implant and procedure solutions to treat Parkinson's disease (PD) and other functional brain disorders.

25 Feb 2013

Circassia announces results from ToleroMune cat allergy phase II clinical study

Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced the results of a phase II clinical study showing that a short course of just four doses of its ToleroMune cat allergy therapy maintained improvements in patients' symptoms two years after the start of treatment.

25 Feb 2013

Omalizumab fast, safe and well-tolerated in teens and adults with chronic spontaneous urticaria

An international team of researchers has found that a once-a-month, high-dose injection of a commonly used asthma drug is highly effective in treating teens and adults chronically afflicted with hives and severe, itchy rash. The drug, omalizumab, was tested on 323 people at 55 medical centers for whom standard antihistamine therapy failed to quell their underlying, allergy-like reaction, known as chronic idiopathic urticaria or chronic spontaneous urticaria.

25 Feb 2013

Study underscores burden that severe hot flashes put on women and society

Hot flashes put a damper on women's health and productivity at work and pump up the cost of health care. A study published online this month in Menopause, the journal of the North American Menopause Society (NAMS), has put some numbers on their impact.

25 Feb 2013

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment.

25 Feb 2013

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

The University of Colorado (CU) has signed exclusive, worldwide licensing and collaboration agreements with rare-disease research-and-development firm Orphan Technologies Ltd to develop an enzyme replacement therapy for Cystathionine Beta-Synthase (CBS) -deficient homocystinuria, a rare, inherited metabolic disease that is often fatal at a young age.

25 Feb 2013