Clinical Trial News and Research

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Duchenne and other dystrophinopathies research receives major boost from new collaboration

Critical Path Institute's (C-Path) Duchenne Regulatory Science Consortium (D-RSC) and the Duchenne Data Foundation (DDF) are excited to announce a joint collaboration aimed at advancing research and improving healthcare for individuals with Duchenne muscular dystrophy (DMD) and other dystrophinopathies (conditions linked to mutations in the DMD gene).

10 Aug 2023

Good Trials Prism: A new partnership to enhance clinical research in low resource settings

Four major clinical trial networks based in low resource settings are embarking on an exciting partnership with the Good Clinical Trials Collaborative to enhance clinical research in low resource settings.

10 Aug 2023

AI tool can quickly diagnose muscle wasting in head and neck cancer patients

Researchers from Dana-Farber Cancer Institute have found a way to use artificial intelligence (AI) to diagnose muscle wasting, called sarcopenia, in patients with head and neck cancer.

10 Aug 2023

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

A personalized therapy selection algorithm for two diabetes type 2 (T2D) treatment drug classes.

10 Aug 2023

Have social determinants of health affected COVID-19 vaccine uptake?

Researchers investigated clinically significant predictors of COVID-19 vaccination uptake among individuals with social and medical susceptibility to SARS-CoV-2 infection.

10 Aug 2023

Low levels of vitamin K linked to poor lung function

People with low levels of vitamin K in their blood are more likely to have poor lung function and to say they suffer with asthma, chronic obstructive pulmonary disease (COPD) and wheezing, according to a study published today (Thursday) in ERJ Open Research.

9 Aug 2023

Immunotherapy after stem cell transplantation effectively combats certain childhood nerve tumors

Scientists at St. Anna Children's Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children.

9 Aug 2023

New treatment approach shows promise in reversing hormone resistance in breast cancer

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

9 Aug 2023

Exercise apps could be a major tool to combat mental health crisis among healthcare workers

Simple home workouts using exercise apps can effectively reduce depressive symptoms in healthcare workers and could be a major tool to combat the global mental health crisis in the sector, says new University of British Columbia research.

9 Aug 2023

Inflammation slows down the development of malaria parasites in bloodstream

Research led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and the Kirby Institute found that inflammation in the body can slow down the development of malaria parasites in the bloodstream – a discovery that may constitute a potential new strategy for preventing or limiting severe disease.

8 Aug 2023

Novel neuromodulation approach leads to gait improvements in patients with Parkinson’s disease

Gait-related disturbances adversely affect the quality of life of patients with Parkinson's disease (PD), a condition affecting millions worldwide.

8 Aug 2023

School-based interventions offer opportunity to promote cardiovascular health in adolescents

Researchers discuss the outcomes of the SI! Program for Secondary Schools trial in adolescence in Spain.

8 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

AI-based predictive tool could help guide treatment of cancer

Researchers at Dana-Farber Cancer Institute have created an AI-based tool that uses tumor gene sequencing data to predict the primary source of a patient's cancer.

7 Aug 2023

New antibody shows promise in reversing carfentanil overdoses

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

7 Aug 2023

Phage therapy shows promise in treating tough Pseudomonas aeruginosa infections

A new international study conducted by the Israeli Phage Therapy Center (IPTC) led by Prof. Ran Nir-Paz at Hadassah Hebrew University Medical Center and Prof. Ronen Hazan of the Faculty of Dental Medicine at The Hebrew University of Jerusalem, using phage PASA16 on compassionate basis to treat tough Pseudomonas aeruginosa infections, has shown promising results with an 86.6% success rate.

7 Aug 2023

Peppermint oil may be new option for pain relief after open heart surgery

The use of essential peppermint oil aromatherapy may ease pain severity after open heart surgery and enhance sleep quality as well, suggest the results of a small comparative clinical trial, published online in the journal BMJ Supportive & Palliative Care.

3 Aug 2023

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has demonstrated that it can predict the outcome of Phase II to Phase III clinical trial success using its proprietary transformer-based AI clinical trial prediction tool called inClinico with a high degree of accuracy.

3 Aug 2023

Children raised in rural areas have better regulated immune systems

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

3 Aug 2023

NIH awards $18 million to develop novel chikungunya vaccine

The Access to Advanced Health Institute (AAHI) announced today that it has received an $18 million award from the National Institutes of Health (NIH) to develop a temperature stable, single-dose vaccine candidate for the chikungunya virus.

3 Aug 2023

Clinical Trial News and Research

Duchenne and other dystrophinopathies research receives major boost from new collaboration

Good Trials Prism: A new partnership to enhance clinical research in low resource settings

AI tool can quickly diagnose muscle wasting in head and neck cancer patients

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

Have social determinants of health affected COVID-19 vaccine uptake?

Low levels of vitamin K linked to poor lung function

Immunotherapy after stem cell transplantation effectively combats certain childhood nerve tumors

New treatment approach shows promise in reversing hormone resistance in breast cancer

Exercise apps could be a major tool to combat mental health crisis among healthcare workers

Inflammation slows down the development of malaria parasites in bloodstream

Novel neuromodulation approach leads to gait improvements in patients with Parkinson’s disease

School-based interventions offer opportunity to promote cardiovascular health in adolescents

Identification of plasma proteins associated with ovarian cancer risk

AI-based predictive tool could help guide treatment of cancer

New antibody shows promise in reversing carfentanil overdoses

Phage therapy shows promise in treating tough Pseudomonas aeruginosa infections

Peppermint oil may be new option for pain relief after open heart surgery

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Children raised in rural areas have better regulated immune systems

NIH awards $18 million to develop novel chikungunya vaccine

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