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Supercomputer simulations reveal potential therapeutic target in HIV-1 replication

HIV-1 replicates in ninja-like ways. The virus slips through the membrane of vital white blood cells. Inside, HIV-1 copies its genes and scavenges parts to build a protective bubble for its copies.

10 Aug 2018

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

Nanoparticles show great promise as diagnostic tools and drug delivery agents. The tiny particles, which scientists can modify with drugs, dyes or targeting molecules, can travel in the circulation and squeeze through small spaces into cells and tissues.

9 Aug 2018

New drug makes rats to self-administer alcohol less frequently

Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns.

9 Aug 2018

Scientists develop 3D-printed implant that could deliver personalized treatment

Southwest Research Institute and The University of Texas at San Antonio are developing a 3D printed implant that, when injected in a patient's body, could deliver a personalized dose of medicine to treat infections as well as ailments such as arthritis, cancer and AIDS.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

New review examines potential of medicinal cannabis to help treat intractable epilepsy

A new British Journal of Clinical Pharmacology review examines the potential of medicinal cannabis--or medical marijuana--for helping patients with intractable epilepsy, in which seizures fail to come under control with standard anticonvulsant treatment.

8 Aug 2018

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Marijuana detection using a breath-analyzer

Marijuana is being increasingly legalized across several states and its use is also on the rise. While 9 states and District of Columbia have legalized recreational marijuana, 30 states and D.C. have legalized medicinal marijuana use.

5 Aug 2018

Digestive hormone influences pancreatic cancer growth and spread

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin, a digestive hormone.

3 Aug 2018

3D-printed implants appear to guide regrowth of missing bone in lab animals

Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while "steadily dissolving," researchers report.

2 Aug 2018

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

A protein known to drive nerve cell survival in the brain and spinal cord might also protect failing hearts in children and young adults with Duchenne muscular dystrophy, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions, a premier global exchange of the latest advances in basic cardiovascular science.

2 Aug 2018

Researchers find possible active substance that may cure hepatitis E

An international team of researchers has now found a possible active substance against the virus in the naturally occurring substance silvestrol.

1 Aug 2018

Pungent compound contained in ginger ensures fresh breath

The pungent compound 6-gingerol, a constituent of ginger, stimulates an enzyme contained in saliva - an enzyme which breaks down foul-smelling substances.

30 Jul 2018

Researchers investigate new treatment that is effective against recurrent breast cancers

What do one in five breast cancers have in common? Large amounts of a protein called HER2 (or human epidermal growth factor receptor 2).

30 Jul 2018

Experimental compound reverses hair loss, skin inflammation related to fatty diet, mice study shows

In a series of experiments with mice, Johns Hopkins investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol.

30 Jul 2018

Fucose-based food supplement could be used to stop the spread of norovirus in children's hospitals

Norovirus is the most common cause of gastroenteritis worldwide; it causes tens hundreds of thousands of deaths each year and is particularly risky for children under 3 years old.

27 Jul 2018

Researchers discover novel antibiotic from leaf of common weed

Researchers working on an SNSF project have discovered novel, antibiotically active chemical substances in a previously rarely explored site: the leaf of a common field weed.

27 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

Researchers develop nano-carriers to specifically target senescent cells

Senescent cells are damaged cells that do not perform their normal roles anymore but that are not dead -hence they are commonly known as zombi cells.

27 Jul 2018

Duke engineers develop new technique to manipulate, split and mix droplets of biological fluids

Engineers at Duke University have developed a way to manipulate, split and mix droplets of biological fluids by having them surf on acoustic waves in oil.

26 Jul 2018

Compound News and Research

Supercomputer simulations reveal potential therapeutic target in HIV-1 replication

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

New drug makes rats to self-administer alcohol less frequently

Scientists develop 3D-printed implant that could deliver personalized treatment

Scientists identify drug that could reverse pulmonary arterial hypertension

New review examines potential of medicinal cannabis to help treat intractable epilepsy

Scientists create new tool to precisely control 3D architecture of linkages in drugs

Marijuana detection using a breath-analyzer

Digestive hormone influences pancreatic cancer growth and spread

3D-printed implants appear to guide regrowth of missing bone in lab animals

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

Researchers find possible active substance that may cure hepatitis E

Pungent compound contained in ginger ensures fresh breath

Researchers investigate new treatment that is effective against recurrent breast cancers

Experimental compound reverses hair loss, skin inflammation related to fatty diet, mice study shows

Fucose-based food supplement could be used to stop the spread of norovirus in children's hospitals

Researchers discover novel antibiotic from leaf of common weed

Bile acids from the gut may offer new treatment for cocaine abuse

Researchers develop nano-carriers to specifically target senescent cells

Duke engineers develop new technique to manipulate, split and mix droplets of biological fluids

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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