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Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke.

25 Sep 2024

Steritas' Pediatric Glucocorticoid Toxicity Index applied in clinical trial to assess steroid-toxicity

Steritas LLC., a company dedicated to enhancing patient care for steroid-treated patients announced that Alder Hey Children’s NHS Foundation Trust, and the Liverpool Clinical Trials Centre will apply its Steritas Pediatric Glucocorticoid Toxicity Index (pGTI) in a clinical trial to compare efficacy, safety and cost-effectiveness of intravenous versus oral glucocorticoids (steroids) for children and young people with Juvenile Idiopathic Arthritis (JIA).

From Steritas LLC 25 Sep 2024

Semaglutide shows promise in treating chronic skin condition in obese patients

A pioneering study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, demonstrates the significant potential of semaglutide in treating hidradenitis suppurative (HS), a common and chronic skin condition, in people with obesity.

24 Sep 2024

Targeted obesity programs reduce lipid-related heart disease risk in children

Researchers assess the lipid profiles of obese children and adolescents and their health implications.

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

Study reveals how inflammatory immune cells enhance prostate cancer resistance

There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully understood.

24 Sep 2024

Space conditions disrupt rhythmic function of bioengineered heart tissues

Johns Hopkins Medicine scientists who arranged for 48 human bioengineered heart tissue samples to spend 30 days at the International Space Station report evidence that the low gravity conditions in space weakened the tissues and disrupted their normal rhythmic beats when compared to earth-bound samples from the same source.

23 Sep 2024

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

Brazil nut consumption in an energy-restricted diet significantly reduced inflammation and improved intestinal permeability in overweight/obese women, likely due to selenium’s anti-inflammatory properties.

23 Sep 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

Chemotherapy linked to increased cardiovascular risks in older cancer survivors

A study based on clinical trial data found higher risks of stroke, heart attack, and hospital admission for heart failure in older cancer survivors.

23 Sep 2024

Florida’s new covid booster guidance is straight-up misinformation

In what has become a pattern of spreading vaccine misinformation, the Florida health department is telling older Floridians and others at highest risk from covid-19 to avoid most booster shots, saying they are potentially dangerous.

23 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Study reveals anti-tumor properties of food antigens

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative medical sciences (IMS) in Japan have discovered that food antigens like milk proteins help keep tumors from growing in our guts, specifically the small intestines.

23 Sep 2024

Cranberry juice: A natural boost for women's skin health

A polyphenol-rich cranberry beverage was found to improve skin elasticity, reduce UV-induced erythema, and modulate the skin microbiome, with effects most pronounced in women aged 40 and older.

22 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024

New two-dose HIV vaccine strategy shows promise for stronger immune response

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, allowing it to evade the antibody response generated by vaccines.

20 Sep 2024

STING protein plays new role in cellular stress clearance and survival

A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell.

20 Sep 2024