B Cell News and Research

RSS

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

A phase III clinical trial of 4,805 women with HER2-positive breast cancer suggests adding a second HER2 targeted medicine, pertuzumab (Perjeta), to standard of care trastuzumab (Herceptin) after surgery may help, although the benefit is modest.

6 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

Researchers discover connection between processes that keep the heart from repairing itself

Heart muscle is one of the least renewable tissues in the body, which is one of the reasons that heart disease is the leading cause of death for both men and women in the United States, according to the Centers for Disease Control and Prevention.

5 Jun 2017

Researchers use gene-editing technique to develop new screening tool for Parkinson's disease

A team of researchers at the University of Central Florida is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system.

5 Jun 2017

New genomic sequencing approach could be first step toward blood tests for early cancer detection

In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high-intensity genomic sequencing approach detected circulating tumor DNA at a high rate.

5 Jun 2017

New targeted oral therapy results in durable responses across many kinds of cancer

Scientists may have developed the first targeted, oral, tumor-type agnostic therapy - a cancer medicine that works comparably well across many kinds of cancer, regardless of patient age. In clinical trials of adults and children with 17 different types of advanced cancer, larotrectinib treatment resulted in responses in 76% of patients.

5 Jun 2017

Researchers receive federal funding to study consequences of West Nile and Zika virus infections

A Georgia State University researcher, in collaboration with researchers at the University of Pennsylvania and Florida State University, has received a five-year, $7.7 million federal grant to study the consequences of West Nile and Zika virus infections on the human central nervous system.

2 Jun 2017

Combination therapy shows potential for effective treatment of RAS-mutant cancers

A study at The University of Texas MD Anderson Cancer Center has shown promise for effective treatment of therapy-resistant cancers caused by a mutation of the RAS gene found in many cancers.

2 Jun 2017

Changes in immune activity appear to signal brain tumor growth five years before diagnosis, study finds

Changes in immune activity appear to signal a growing brain tumor five years before symptoms arise, new research has found.

2 Jun 2017

Fertility preservation presents important ethical issues for children with DSD

Children with differences of sex development (DSD) are born with reproductive organs that are not typically male or female. They may face infertility from abnormal development of testes or ovaries, and in some patients these organs are surgically removed to prevent an increased risk of germ cell cancer.

2 Jun 2017

Mouse model could improve understanding of human brown fat’s role in metabolic processes

When it gets cold around you, your body turns up the heat to maintain its normal temperature. The heat is produced by brown adipose tissue, or brown fat, which also plays a role in how the body uses glucose and fat.

2 Jun 2017

Olive oil component may help prevent cancer developing in the brain

A compound found in olive oil may help to prevent cancer developing in the brain, a study shows. Research into oleic acid -- the primary ingredient in olive oil -- has shown how it can help prevent cancer-causing genes from functioning in cells.

2 Jun 2017

Tumorigenesis may be induced from neighboring tissues, study suggests

Current view is that cancer development is initiated from cells that acquire initial DNA mutations. These in turn provoke additional defects, and ultimately the affected cells begin to proliferate in an uncontrolled manner to develop primary tumors.

2 Jun 2017

University of Redlands researchers discover critical process in pharmaceutical drug development

A faculty-student research team in the chemistry lab at the University of Redlands has advanced a new approach to a critical process in pharmaceutical drug development that could reduce the time and cost of bringing a drug from concept to market.

2 Jun 2017

Scientists locate crucial off-switch for central cell control

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes array.

2 Jun 2017

Scientists create new method to make peptide stapling widely available

UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.

2 Jun 2017

Assessing safety and toxicity of bioactives could be key to establishing tolerable upper intake levels

The good news is out that wine and dark chocolate may be good for your health. That's because of substances known as bioactives that are contained in those foods.

2 Jun 2017

Bacterial cell factories produce enzymes that can be used as active ingredients in drugs

Researchers at the Novo Nordisk Foundation Center for Biosustainability in Denmark have developed a method of producing P450 enzymes - used by plants to defend against predators and microbes - in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.

2 Jun 2017

ATCC and One Codex form partnership to address microbiome research needs

ATCC, a global leader in biological materials development, management and standards, and One Codex, a leading microbial genomics and metagenomics platform, today announced the formation of a partnership to address microbiome research needs.

2 Jun 2017

Study underlines significance of microglia for homeostasis in the brain

The role of microglial cells in neurodegenerative disease is not fully understood. But new results from researchers in Munich and Basel suggest that stimulation of this arm of the immune system might well delay the onset of such disorders.

2 Jun 2017

B Cell News and Research

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Researchers discover connection between processes that keep the heart from repairing itself

Researchers use gene-editing technique to develop new screening tool for Parkinson's disease

New genomic sequencing approach could be first step toward blood tests for early cancer detection

New targeted oral therapy results in durable responses across many kinds of cancer

Researchers receive federal funding to study consequences of West Nile and Zika virus infections

Combination therapy shows potential for effective treatment of RAS-mutant cancers

Changes in immune activity appear to signal brain tumor growth five years before diagnosis, study finds

Fertility preservation presents important ethical issues for children with DSD

Mouse model could improve understanding of human brown fat’s role in metabolic processes

Olive oil component may help prevent cancer developing in the brain

Tumorigenesis may be induced from neighboring tissues, study suggests

University of Redlands researchers discover critical process in pharmaceutical drug development

Scientists locate crucial off-switch for central cell control

Scientists create new method to make peptide stapling widely available

Assessing safety and toxicity of bioactives could be key to establishing tolerable upper intake levels

Bacterial cell factories produce enzymes that can be used as active ingredients in drugs

ATCC and One Codex form partnership to address microbiome research needs

Study underlines significance of microglia for homeostasis in the brain

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News