Therapy News and Research

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Tranexamic acid role in coronary bypass surgery

Tranexamic acid balances the increased bleeding risk associated with recent clopidogrel use in patients undergoing on-pump coronary artery bypass grafting, shows a randomized trial.

7 Mar 2013

Taping improves ROM effects of Mulligan’s Mobilisation-with-Movement

Combining the Mulligan’s Mobilisation-with-Movement technique for the shoulder with taping provides a sustained improvement in range of movement for up to a week that is superior to that with Mobilisation-with-Movement alone, researchers report.

7 Mar 2013

Genomic analysis could illuminate more options in developing precise treatments for cancer

Investigators working on the precision medicine initiative at The Cancer Institute of New Jersey are embarking on a genomic analysis study which could illuminate more options in developing personalized and precise treatments for cancer patients.

7 Mar 2013

RA patients who initiate anti-TNF therapies do not have higher risk of shingles: Study

Although patients with rheumatoid arthritis have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other inflammatory diseases found that those who initiated anti-tumor necrosis factor therapies were not at higher risk of herpes zoster compared with patients who initiated nonbiologic treatment regimens, according to a study appearing in the March 6 issue of JAMA.

7 Mar 2013

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Kidney failure affects 25 million individuals in the U.S. and many more throughout the world. Loss of kidney function means the majority of these patients must undergo dialysis treatments to remove excess fluids and waste products. Although dialysis therapy coupled with medication has improved the life expectancy for people with kidney failure, for unknown reasons, patients' risk of sudden heart failure and death remains 10 to 20 times greater than average.

7 Mar 2013

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy (DMD).

7 Mar 2013

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

In a world first, a team of researchers at the Krembil Neuroscience Centre and the University Health Network have shown that Deep Brain Stimulation (DBS) in patients with chronic, severe and treatment-resistant Anorexia Nervosa (anorexia) helps some patients achieve and maintain improvements in body weight, mood, and anxiety.

6 Mar 2013

FDA accepts AMAG’s Feraheme sNDA for review

AMAG Pharmaceuticals, Inc. today announced that the United States Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use, which was submitted to the FDA in December 2012.

6 Mar 2013

Zinc protoporphyrin a marker for iron deficiency in low-income children

Researchers say that zinc protoporphyrin could be a useful measure for screening infants from low-income families for iron deficiency, as well as for monitoring response to therapy, especially among children with anemia.

6 Mar 2013

Fewer malaria cases, more artesunate resistance on Thai border

Results from an observational study show that the number of reported malaria cases in children and pregnant women on the Thai–Myanmar border has decreased significantly over the past decade.

6 Mar 2013

Drug to relieve pain of feline osteoarthritis identified

The non-steroidal anti-inflammatory drug meloxicam significantly improves nighttime physical activity in cats with osteoarthritis, indicating its potential as a pain reliever in this feline population, report Canadian researchers.

6 Mar 2013

Prostate tissue androgen content predicts ADT outcome

Determining the androgen content in prostate tissue could predict patients’ responses to androgen deprivation therapy and the risk for castration-resistant prostate cancer, show study findings.

6 Mar 2013

Pain self-management and exercise ‘effective in elderly’

Techniques for the self-management of chronic pain based on cognitive behavioral therapy significantly reduce disability, suggest results from a randomized controlled trial in older adults.

6 Mar 2013

Prevention remains best method to stop mother-to-child HIV transmission

"If confirmed by further analysis," the case of a Mississippi infant being cured of HIV "would be the first time a person has been cured with simple drug treatments, making a lifetime of antiviral therapy unnecessary," a New York Times editorial states.

6 Mar 2013

Focal laser ablation uses targeted heat to burn away cancerous cells in prostate

Men with low-risk prostate cancer who previously had to choose between aggressive treatment, with the potential for significant side effects, and active surveillance, with the risk of disease progression, may have a new option.

6 Mar 2013

Wayne State receives U.S. patent allowance for vision restoration technology

Technology to restore vision through the use of a component of green algae developed by Dr. Zhou-Han Pan, professor and scientific director of the Ligon Research Center of Vision at the Kresge Eye Institute at Wayne State University, and licensed to RetroSense Therapeutics, a biotechnology company dedicated to developing gene therapy approaches to vision restoration, announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance for U.S. patent application (No. 12/299,574).

6 Mar 2013

Therapy News and Research

Tranexamic acid role in coronary bypass surgery

Taping improves ROM effects of Mulligan’s Mobilisation-with-Movement

Genomic analysis could illuminate more options in developing precise treatments for cancer

RA patients who initiate anti-TNF therapies do not have higher risk of shingles: Study

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

FDA accepts AMAG’s Feraheme sNDA for review

Zinc protoporphyrin a marker for iron deficiency in low-income children

Fewer malaria cases, more artesunate resistance on Thai border

Drug to relieve pain of feline osteoarthritis identified

Prostate tissue androgen content predicts ADT outcome

Pain self-management and exercise ‘effective in elderly’

Prevention remains best method to stop mother-to-child HIV transmission

Focal laser ablation uses targeted heat to burn away cancerous cells in prostate

Wayne State receives U.S. patent allowance for vision restoration technology

Aerobic walking program alleviates lower back pain, says Tel Aviv University researcher

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

New research findings could lead to development of effective therapies for anxiety disorders

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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