Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New test could enable early detection of ovarian cancer

Researchers from Queen's University Belfast have developed a test that may be able to detect ovarian cancer up to two years earlier than current approaches.

23 Aug 2019

Largest genomic analysis could help improve treatment for Merkel cell carcinoma patients

Merkel cell carcinoma is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each year in the United States.

20 Aug 2019

New painless skin patch can speed up diagnostic testing

Many diagnostic tests require blood, but NIBIB-funded researchers have developed a skin patch with tiny needles that painlessly collect interstitial fluid (ISF) for testing.

19 Aug 2019

Study provides new insight into regional survival differences in glioblastoma

A team of researchers from Osaka University, in cooperation with the Institute for Clinical Research and medical institutes participating in the Kansai Molecular Diagnosis Network for CNS Tumors, conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma, proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an original Japanese cohort and a dataset from The Cancer Genome Atlas.

19 Aug 2019

FDA approves novel device to treat symptoms associated with advanced heart failure

The U.S. Food and Drug Administration today approved the Barostim Neo System for the improvement of symptoms in patients with advanced heart failure who are not suited for treatment with other heart failure devices, such as cardiac resynchronization therapy.

18 Aug 2019

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

A new fruit fly model that mimics diseases associated with high uric acid levels, such as gout and kidney stones, has revealed new targets for developing treatments for these diseases.

From PLOS ONE 16 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

Quanterix announces closing of public offering including exercise of underwriters’ option to purchase additional shares

Quanterix announce the closing of its previously announced underwritten public offering of 2,732,673 shares of its common stock.

From Quanterix 13 Aug 2019

Study shows potential of crucial signaling pathway as biomarker, therapeutic target for cancer

A crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by cancer cells to put the brakes on the immune system, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

9 Aug 2019

New discovery could help doctors identify children at risk for Wilms’ tumor relapse

Today, researchers from MSK Kids at Memorial Sloan Kettering Cancer Center published results that examine elevated levels of a protein called prohibitin in the urine and tumors of children with Wilms' tumors.

9 Aug 2019

Quanterix prices public offering of common stock

Quanterix announce pricing of previously announced underwritten public offering of 2,376,238 shares of common stock public offering price of $25.25 per share.

From Quanterix 9 Aug 2019

Three new early-career investigators join federally funded precision medicine initiative

Three new early-career investigators have been selected to be a part of the University of Kansas Medical Center's $11.5 million precision medicine-focused federal grant.

9 Aug 2019

Eye-movement tests provide reliable biomarker of individual acute sleep loss

Lack of sleep can be dangerous; it is thought to play a role in up to 30% of all motor vehicle crashes and even implicated in catastrophic events, such as the Chernobyl nuclear disaster.

8 Aug 2019

Blood clotting proteins in urine act as potent biomarkers for lupus

The team of researchers at the University of Houston found that blood clotting proteins, both the ones that promote blood clotting (prothrombic) and those that disperse them (thrombolytic) are elevated in the urine of patients with lupus nephritis (LN).

7 Aug 2019

Quanterix announces proposed public offering of common stock

Quanterix announced that it has commenced an underwritten public offering of $75 million of shares of its common stock.

From Quanterix 7 Aug 2019

FDG-PET/CT may assist in surgical planning for head and neck cancer

The Journal of Clinical Oncology has published the results of the largest prospective multicenter trial conducted of FDG-PET/CT in head and neck cancer, providing rigorous data about its performance.

7 Aug 2019

Researchers discover blood clotting proteins in urine as biomarkers of lupus nephritis

University of Houston researcher Chandra Mohan is reporting in Arthritis Research and Therapy that clotting proteins, both those that promote blood clots (pro-thrombotic) and those that work to dissipate them (thrombolytic), are elevated in the urine of patients who suffer from lupus nephritis (LN).

7 Aug 2019

Quanterix corporation releases operating results for second quarter 2019

Quanterix announced financial results for the three and six months ended June 30, 2019.

From Quanterix 6 Aug 2019

New research explains why some cancers don't respond to immunotherapy

New research has uncovered a mechanism thought to explain why some cancers don't respond to a widely used form of immunotherapy called "checkpoint inhibitors" or anti-PD-1.

6 Aug 2019

Biomarkers reveal increase in thyroid cancer incidence among WTC responders

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population.

5 Aug 2019