Clinical Trial News and Research

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Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Skipping genetic counseling does not increase distress for ovarian or breast cancer screening

Skipping genetic counseling before or after taking a remote screening of inherited risk for ovarian or breast cancer does not increase distress, anxiety or depression, according to a study published Sept. 14 in JAMA Oncology.

21 Sep 2023

USC develops innovative system for conducting preclinical research on potential stroke treatments

To test new stroke treatments, a research team from the Keck School of Medicine of USC develops a more rigorous system for conducting preclinical research that could lead to more successful clinical trials.

20 Sep 2023

Cognitive behavioral therapy can significantly reduce the burden of fibromyalgia

Patients living with fibromyalgia (FM) – a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog – often find limited treatment options and a scarcity of explanations for their symptoms.

20 Sep 2023

Cognitive-behavioral therapy reduces the interfering effects of fibromyalgia pain

In a recent randomized clinical trial of patients with fibromyalgia, cognitive-behavioral therapy (CBT) - which uses structured techniques to alter distorted thoughts and negative moods - was superior to a matched education treatment in reducing the interfering effects of pain and other aspects of fibromyalgia on daily living.

20 Sep 2023

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced a $6.2 million grant from the Steven & Alexandra Cohen Foundation.

20 Sep 2023

Unveiling the role of EBV in the onset and progression of multiple sclerosis

Recent evidence strongly implicates infection by the Epstein-Barr virus (EBV) as the trigger for development of multiple sclerosis (MS). An international research team is now gathering to unveil the role of EBV in the onset and progression of the MS disease.

20 Sep 2023

Early treatment with convalescent plasma may reduce risk of long COVID

Findings from a nationwide, multicenter study led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health suggest that patients with COVID-19 have less chance of developing post-COVID conditions - commonly known as long COVID - if they receive early treatment with plasma from convalescent (recovered) COVID patients that contain antibodies against SARS-CoV-2, the virus that causes COVID-19.

20 Sep 2023

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

20 Sep 2023

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

The association between BNT162b2 vaccine and (COVID-19)-related ambulatory visits.

20 Sep 2023

CST and Leica Biosystems partner to enable companion diagnostics for personalized medicine

Cell Signaling Technology (CST), a life science discovery technology company and leading provider of antibodies, kits, and services, is partnered with Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, to support the development of companion diagnostics (CDx) assays using the extensive portfolio of best-in-class antibodies from CST validated for immunohistochemistry (IHC).

From Cell Signaling Technology 20 Sep 2023

UCR researcher receives $3 million grant to prevent alcohol abuse among Pacific Islander young adults

In previous research, Andrew Subica and his colleagues found exceptionally high rates of alcohol use disorder (or alcohol abuse) and alcohol-related harms among Pacific Islander young adults.

19 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Amoxicillin vs. amoxicillin-clavulanate: Which is more effective for acute sinusitis in children?

Brigham researchers found that patients prescribed amoxicillin-clavulanate had higher rates of gastrointestinal symptoms and yeast infections than those prescribed amoxicillin.

19 Sep 2023

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

The neutralizing antibodies persistence of the Sabin strain-derived inactivated poliovirus vaccine.

19 Sep 2023

Save billions or stick with Humira? Drug brokers steer Americans to the costly choice

Tennessee last year spent $48 million on a single drug, Humira — about $62,000 for each of the 775 patients who were covered by its employee health insurance program and receiving the treatment.

19 Sep 2023

Does a high-dose influenza vaccine reduce cardiovascular disease risk?

Whether a high-dose influenza vaccine is associated with a benefit in reducing CP events.

19 Sep 2023

First real-world observational study of the JADA®System, a medical device to control postpartum hemorrhage (PPH), published in ACOG’s Obstetrics & Gynecology

Organon today announced that Obstetrics & Gynecology, the peer-reviewed journal of the American College of Obstetrics and Gynecology (ACOG), published the results of the RUBY study which reached its primary effectiveness outcome of successfully treating abnormal postpartum uterine bleeding and postpartum hemorrhage with the JADA® System.

19 Sep 2023

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.

19 Sep 2023

Clinical Trial News and Research

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Skipping genetic counseling does not increase distress for ovarian or breast cancer screening

USC develops innovative system for conducting preclinical research on potential stroke treatments

Cognitive behavioral therapy can significantly reduce the burden of fibromyalgia

Cognitive-behavioral therapy reduces the interfering effects of fibromyalgia pain

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Unveiling the role of EBV in the onset and progression of multiple sclerosis

Early treatment with convalescent plasma may reduce risk of long COVID

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

CST and Leica Biosystems partner to enable companion diagnostics for personalized medicine

UCR researcher receives $3 million grant to prevent alcohol abuse among Pacific Islander young adults

Transforming postpartum depression treatment with neurosteroids

Amoxicillin vs. amoxicillin-clavulanate: Which is more effective for acute sinusitis in children?

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

Save billions or stick with Humira? Drug brokers steer Americans to the costly choice

Does a high-dose influenza vaccine reduce cardiovascular disease risk?

First real-world observational study of the JADA®System, a medical device to control postpartum hemorrhage (PPH), published in ACOG’s Obstetrics & Gynecology

New treatment approach effectively treats the most aggressive forms of prostate cancer

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