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Nanorods of gold blast tumor cells

Researchers have shown how tiny "nanorods" of gold can be triggered by a laser beam to blast holes in the membranes of tumor cells, setting in motion a complex biochemical mechanism that leads to a tumor cell's self-destruction.

17 Oct 2007

New near-infrared contrast agent reveals bone and breast-cancer-related microcalcifications

Mammography continues to be the method of choice for the early detection of breast cancer. However, because this technique is not as selective or specific as one would wish, and does not deliver reliable results for every level of tissue density, alternatives are being sought.

15 Oct 2007

How does the opioid system work?

The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).

15 Oct 2007

Brookhaven microgrid allows simultaneous study of multiple variables

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a method for correlating the results of microscopic imaging techniques in a way that could lead to improved understanding, diagnosis, and possibly treatment of a variety of disease conditions, including Alzheimer's disease. The Laboratory has filed a U.S. provisional patent application for the invention.

10 Oct 2007

Biosensors to monitor blood sugar in diabetics

There is a need today to be able to measure various concentrations of blood sugar in fluid, especially in the foodstuffs industry and health care.

9 Oct 2007

Fraunhofer pharmaceutical agent speeds drug development

It takes a great deal of time and money to develop a new drug. At Biotechnica in Hanover from October 9 to 11, the Fraunhofer Life Sciences Alliance will demonstrate how a pharmaceutical agent can make its way more quickly from the research laboratory to the pharmacy.

8 Oct 2007

Researchers create modular, multi-functional drug delivery system

There are two aspects to creating an effective drug: finding a chemical compound that has the desired biological effect and minimal side-effects and then delivering it to the right place in the body for it to do its job.

8 Oct 2007

New test detects the presence of biogenic amines

Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those 'out of the blue' headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.

2 Oct 2007

Botched production of insulin molecule may lead to diabetes

Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked.

2 Oct 2007

Evaluation of poly(glycerol adipate) nanoparticle uptake in an in vitro 3-D brain tumor co-culture model

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

27 Sep 2007

In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles

Most people think of hydrogen peroxide as a topical germ killer, but the medicine cabinet staple is gaining steam in the medical community as an early indicator of disease in the body.

27 Sep 2007

New nanoprobe imaging station helps study the distribution of elements in cells

Scientists suspect that iron accumulation plays a role in neurodegenerative processes such as Parkinson's disease, but its distribution in neurons has never been observed because of the lack of techniques to do so. Until today.

26 Sep 2007

Fluorescence resonance energy transfer technology shows how cancer may take hold

A team, led by researchers at the Carnegie Institution,* has found a key biochemical cycle that suppresses the immune response, thereby allowing cancer cells to multiply unabated.

26 Sep 2007

Viewing dye-packed vesicles causes them to explode

It's a long-standing question: Can just the act of observing an experiment affect the results, According to a new study by Rockefeller University scientists, if the experiment uses a fluorescent dye called acridine orange, the answer is a resounding yes."

25 Sep 2007

Scientists capture first optical images of carbon nanotubes inside a living organism

Using fruit flies, the researchers confirmed that a technique developed at Rice -- near-infrared fluorescent imaging -- was capable of detecting DNA-sized nanotubes inside living fruit flies.

25 Sep 2007

Process of necrosis redefined in landmark study

A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.

21 Sep 2007

Rapid testing for pre-natal detection of Down syndrome

Scientists in California are reporting an advance toward rapid testing for pre-natal detection of Down syndrome and other birth defects that involve an abnormal number of chromosomes.

18 Sep 2007

Scientists isolate stem cells in womb tissue

Scientists in Australia have found a way of identifying probable stem cells in the lining of women's wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors.

13 Sep 2007

New technique detects how proteins undergo changes inside a cell

In the September issue of Molecular & Cellular Proteomics , scientists describe a new technique that can detect how proteins undergo changes inside a cell.

13 Sep 2007

Novel enzyme may offer huge range of potential therapeutic agents

By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties.

10 Sep 2007