Inflammation News and Research

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Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

Study reveals biomarkers that predict disability worsening in multiple sclerosis

A pioneering study presented today at ECTRIMS 2024 has identified critical biomarkers that can predict disability worsening in multiple sclerosis (MS).

19 Sep 2024

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time.

19 Sep 2024

Immune proteins in tooth enamel provide clues about ancient human health

A new way of looking at tooth enamel could give scientists a path to deeper understanding of the health of human populations, from the ancient to the modern.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

FIND Lp(a) machine learning model aims to transform cardiovascular disease screening

Today, the Family Heart Foundation®, a leading research and advocacy organization, announced the successful completion of the Flag, Identify, Network and Deliver™ “FIND Lp(a)” machine learning model – a first-of-its-kind offering being implemented in care delivery systems across the United States.

19 Sep 2024

Hypoxia's hidden role in boosting anti-cancer immunity

In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.

19 Sep 2024

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Rice University and Baylor College of Medicine have received $2.8 million in funding from the National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), for research on reducing inflammation and lung damage in acute respiratory distress syndrome (ARDS) patients.

19 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Researchers discovered that IBD significantly increases the risk of developing T1D, and this association works both ways, independent of genetics and familial factors. The strongest link was seen in ulcerative colitis patients.

19 Sep 2024

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Researchers explore the global rise in early-onset cancers, linking environmental exposures and lifestyle changes to the surge, and advocate for tailored prevention and treatment strategies.

18 Sep 2024

Triptans prove to be more effective for acute migraines than newer drugs

Some triptans are a more effective treatment for acute migraines than newer, more expensive drugs, finds an analysis of the latest evidence published by The BMJ today.

18 Sep 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Low serum sodium concentrations in blood are called hyponatremia, a prevalent clinical electrolyte disorder.

18 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

Air pollution drives higher Parkinson’s risk and worsens symptoms in affected patients

Higher air pollution levels, particularly PM2.5 and NO2, significantly increase the risk of Parkinson's disease and worsen clinical outcomes like dyskinesia.

17 Sep 2024

UCLA study links childhood trauma to sex-specific health risks later in life

A new study led by UCLA Health found that a person's sex and their unique experiences of childhood trauma can have specific consequences for their biological health and risk of developing 20 major diseases later in life.

17 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Loneliness may not be a direct cause of disease

A study reveals loneliness correlates with 13 illness categories, highlighting its role as a potential proxy marker rather than a direct risk factor.

17 Sep 2024

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic dysfunction-associated steatotic liver disease).

17 Sep 2024

Inflammation News and Research

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Study reveals biomarkers that predict disability worsening in multiple sclerosis

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Immune proteins in tooth enamel provide clues about ancient human health

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

FIND Lp(a) machine learning model aims to transform cardiovascular disease screening

Hypoxia's hidden role in boosting anti-cancer immunity

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Triptans prove to be more effective for acute migraines than newer drugs

Leptin variations may influence brain health and dementia development

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Air pollution drives higher Parkinson’s risk and worsens symptoms in affected patients

UCLA study links childhood trauma to sex-specific health risks later in life

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Loneliness may not be a direct cause of disease

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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