Clinical Trial News and Research

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New class of antibody could benefit patients with treatment-resistant cancers

A Cancer Research UK-funded clinical trial has shown, for the first time, that a new class of antibody could benefit cancer patients whose existing treatments have stopped working.

28 Jul 2023

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Osivax, a biopharmaceutical company developing vaccines to provide broad-spectrum protection against highly mutating infectious viruses, today announced that The Lancet Infectious Diseases published results from the company's OVX836-003 study under the title, "Immunogenicity, safety and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: randomized, double-blind placebo-controlled, Phase 2a trial."

27 Jul 2023

Long-term commitment to MIND diet needed for reaping brain health benefits

New research shows the importance of long-term commitment to the MIND diet for reaping the greatest benefit to brain health.

27 Jul 2023

Susan G. Komen announces fourth grant for metastatic breast cancer research

Susan G. Komen, the world's leading breast cancer organization, announced the fourth MBC-focused research grant supported through the Komen Metastatic Breast Cancer Collaborative Research Initiative (MBCCRI), a collaboration between Komen, Duke Cancer Institute and the University of North Carolina Lineberger Comprehensive Cancer Center, which pairs researchers from each of the organizations to work together and address significant gaps in our knowledge about MBC to advance patient care and improve patient outcomes.

27 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

Experts weigh benefits and risks of new Alzheimer's disease therapies

New therapies for early Alzheimer's disease, monoclonal antibodies that remove amyloid-β plaques in the brain, are bringing hope to people whose lives have been affected by the disease.

26 Jul 2023

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

A new study led by researchers at The University of Texas MD Anderson Cancer Center discovered loss of metabolic fitness in chimeric antigen receptor (CAR) natural killer (NK) cells is a critical mechanism of resistance, with infused cells gradually losing the ability to compete with tumor cells for nutrients, leading to tumor relapse.

26 Jul 2023

More steps linked to improved health for heart failure patients

KIAA0930 could be a novel therapeutic target for cancer cachexia

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells."

26 Jul 2023

American Heart Association grants $2.1 million to study migraines and cardiovascular disease

Existing research shows certain types of migraines can increase the risk of stroke, and there is growing evidence that they may also lead to other types of cardiovascular disease (CVD).

26 Jul 2023

Researchers make breakthrough in fight against mucosal melanoma

Although rare, mucosal melanoma in humans has a low survival rate. It has been difficult to investigate due to a lack of similar cancers in animals for study.

26 Jul 2023

Study reveals key mechanism linking obstructive sleep apnea and cardiovascular disease

Researchers have found that people with obstructive sleep apnea have an increased cardiovascular risk due to reduced blood oxygen levels, largely explained by interrupted breathing.

26 Jul 2023

Does a multidomain intervention of aerobic-resistance exercises with cognitive training and vitamin D improve cognition in older adults with mild cognitive impairment?

Researchers used a SYNERGIC Trial to evaluate the efficacy of a combination of cognitive training, progressive exercise, and vitamin D supplementation on reversing the effects of mild cognitive impairment in adults

26 Jul 2023

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

An injectable biomaterial activated by pulses of low-energy blue light has tremendous potential for on-the-spot repair to the domed outer layer of the eye, a team of University of Ottawa researchers and their collaborators have revealed.

26 Jul 2023

Drug interferon proven effective to reduce the spread of COVID-19

Results of an innovative clinical trial led by Perth researchers have shown that the drug interferon could help reduce the spread of COVID-19 from a positive person to their household contacts, with the study helping to inform treatment options for a future pandemic.

26 Jul 2023

Comparing the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and a toothpaste with sodium fluoride

The study aimed to compare the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and toothpaste with sodium fluoride.

25 Jul 2023

Consuming strawberries may promote cognitive function and improve cardiovascular risk factors

Daily strawberry consumption was linked to improved cognitive function, lower blood pressure and higher antioxidant capacity in a randomized clinical trial presented today at Nutrition 2023, the annual meeting of the American Society of Nutrition.

24 Jul 2023

Dealcoholized muscadine wine may improve skin elasticity

Could muscadine wine help perk up sagging skin? According to a new study, women who drank two glasses of dealcoholized muscadine wine daily showed significant improvements in the elasticity and water retention of their skin compared with those who consumed a placebo.

24 Jul 2023

Probiotic may help prevent cognitive decline during aging

Findings from a new study suggest that taking a probiotic could help prevent the decline in memory and thinking that can accompany aging.

24 Jul 2023

New class of cholesterol-lowering drugs can affect lung function and brain size, study finds

One of the world’s largest studies on the impact of cholesterol-lowering medication has highlighted an issue with a new class of drugs that could impair lung function in some patients.

24 Jul 2023

Clinical Trial News and Research

New class of antibody could benefit patients with treatment-resistant cancers

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Long-term commitment to MIND diet needed for reaping brain health benefits

Susan G. Komen announces fourth grant for metastatic breast cancer research

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

Experts weigh benefits and risks of new Alzheimer's disease therapies

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

More steps linked to improved health for heart failure patients

KIAA0930 could be a novel therapeutic target for cancer cachexia

American Heart Association grants $2.1 million to study migraines and cardiovascular disease

Researchers make breakthrough in fight against mucosal melanoma

Study reveals key mechanism linking obstructive sleep apnea and cardiovascular disease

Does a multidomain intervention of aerobic-resistance exercises with cognitive training and vitamin D improve cognition in older adults with mild cognitive impairment?

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

Drug interferon proven effective to reduce the spread of COVID-19

Comparing the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and a toothpaste with sodium fluoride

Consuming strawberries may promote cognitive function and improve cardiovascular risk factors

Dealcoholized muscadine wine may improve skin elasticity

Probiotic may help prevent cognitive decline during aging

New class of cholesterol-lowering drugs can affect lung function and brain size, study finds

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