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Myriad biological, societal factors that impact CKD severity for children of African descent

Myriad biological and societal factors can impact the occurrence and accelerate progression of chronic kidney disease for children of African descent - including preterm birth, exposure to toxins during gestation and lower socioeconomic status - and can complicate these children's access to effective treatments, according to an invited commentary published in the November 2018 edition of American Journal of Kidney Diseases.

21 Nov 2018

Vanderbilt researchers isolate antibody that can neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

21 Nov 2018

First modeling system developed for testing age-specific human immune responses to vaccines

A team of scientists at Boston Children's Hospital has developed the first modeling system for testing age-specific human immune responses to vaccines -- outside the body. The practical, cost-effective new platform, using all human components, is expected to accelerate and de-risk the development, assessment and selection of vaccines.

20 Nov 2018

Routine HCV testing in correctional facilities can best identify and treat disease, say researchers

Results from a new study led by Boston Medical Center (BMC) found routine Hepatitis C testing identified a significant number of cases that would have been missed by targeted testing among a population of individuals in Washington State prisons.

20 Nov 2018

AHF commends the passage of global AIDS funding in the House, calls for swift approval

AIDS Healthcare Foundation (AHF) today praised the U.S. House of Representatives for unanimously approving H.R. 6651, the PEPFAR Extension Act of 2018 (H.R. 6651) on November 13.

20 Nov 2018

Individuals identified as lesbian, gay more likely to misuse opioids than heterosexual

Men and women who identify as lesbian, gay, or bisexual are more likely to misuse opioids when compared with those who identify as heterosexual, a new study shows.

19 Nov 2018

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

EMA recommends first all-oral treatment to tackle deadly sleeping sickness

The European Medicines Agency's Committee for Medicinal Products for Human Use has adopted a positive scientific opinion of fexinidazole, the first all-oral treatment that has been shown to be efficacious for both stages of sleeping sickness.

16 Nov 2018

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, and colleagues.

16 Nov 2018

IDSA guidelines: Review by ID physician improves outcomes for outpatient parenteral antimicrobial therapy

Before patients receive intravenous antimicrobial infusion therapy outside of the hospital - whether at home, a doctor's office or a skilled nursing facility - an infectious diseases specialist should review the order to ensure the most appropriate treatment, suggest updated guidelines released by the Infectious Diseases Society of America.

14 Nov 2018

An underused strategy for surge in STDs: Treat patients’ partners without a doctor visit

If patients return to Dr. Crystal Bowe soon after taking medication for a sexually transmitted infection, she usually knows the reason: Their partners have re-infected them.

13 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

New study does not support hypertensive effect from urate elevation

A study from a group of Massachusetts General Hospital investigators may reduce the concern that elevating levels of urate, an approach being investigated to treat several neurodegenerative disorders, could increase the risk of hypertension.

8 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

HIV-2 is more pathogenic than previously demonstrated, finds study

A study published in The Lancet HIV shows that HIV-2 is more pathogenic than previously demonstrated. The new findings indicate that early treatment should be applied to all patients with HIV, not only to those with HIV-1.

7 Nov 2018

ECDC study estimates burden of infections caused by antibiotic-resistant bacteria

An ECDC study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area.

6 Nov 2018

New encyclopedia for adult and pediatric neuropsychological disorders

John DeLuca, PhD, a clinical neuropsychologist and Senior Vice President of Research and Training at Kessler Foundation, is the co-chief editor of the new 2nd edition "Encyclopedia of Clinical Neuropsychology". Published by Springer, it is the first major encyclopedia of adult and pediatric neuropsychological disorders.

2 Nov 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

PrEP shown to be safe and effective for widespread use

New research presented at the HIV Drug Therapy Conference in Glasgow today shows that pre-exposure prophylaxis could be given to millions of people worldwide with no increased risk of safety issues during treatment.

30 Oct 2018

HIV News and Research

Myriad biological, societal factors that impact CKD severity for children of African descent

Vanderbilt researchers isolate antibody that can neutralize West Nile virus

First modeling system developed for testing age-specific human immune responses to vaccines

Routine HCV testing in correctional facilities can best identify and treat disease, say researchers

AHF commends the passage of global AIDS funding in the House, calls for swift approval

Individuals identified as lesbian, gay more likely to misuse opioids than heterosexual

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

EMA recommends first all-oral treatment to tackle deadly sleeping sickness

Mechanisms that govern HIV latency differ in the gut and blood, finds study

IDSA guidelines: Review by ID physician improves outcomes for outpatient parenteral antimicrobial therapy

An underused strategy for surge in STDs: Treat patients’ partners without a doctor visit

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

New study does not support hypertensive effect from urate elevation

Monash researchers provide insight into intricate peptide changes affecting immune system

Oral antibiotic shows promise to cure uncomplicated gonorrhea

HIV-2 is more pathogenic than previously demonstrated, finds study

ECDC study estimates burden of infections caused by antibiotic-resistant bacteria

New encyclopedia for adult and pediatric neuropsychological disorders

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

PrEP shown to be safe and effective for widespread use

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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