Immune Response News and Research

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Researchers find muscle growth in some critically ill COVID-19 patients

Muscles appear to grow, rather than shrink, in some critically ill COVID-19 patients, finds new research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care, held online this year.

17 Dec 2021

University of Birmingham launches 5 new major studies focused on management of type 1 diabetes

The University of Birmingham today announces the launch of five new major studies aimed at improving the prevention, treatment and management of type 1 diabetes – with a particular focus on children and young adults.

17 Dec 2021

Efficacy of NVX-CoV2373 in the US and Mexican adult population

A new study has described the results of PREVENT-19, a phase 3 trial of NVX-CoV2373 that included all adults in the United States and Mexico.

17 Dec 2021

Investigating potential cross-protection against SARS-CoV-2 after previous exposure to bovine coronavirus

Researchers have conducted an investigation to probe the similarity of viral epitopes between bovine coronavirus (BCoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Dec 2021

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Researchers investigated the mutations reported in the Omicron variant and its likely impact on the use of therapeutic antibodies in COVID-19 treatment as well as on vaccinated individuals.

17 Dec 2021

Analysis of the alteration of neutralizing titers with Omicron pseudovirus

A new study measured antibody levels from blood samples of vaccinated individuals and individuals who recovered from COVID-19 illness.

17 Dec 2021

Study provides a more effective treatment approach to preventing graft-versus-host-disease

A new study led by UC Davis Health researchers showed that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease (GVHD), an inflammatory condition that develops in patients after their allogeneic hematopoietic stem cell transplantation (allo-HSCT).

16 Dec 2021

New study demonstrates SARS-CoV-2 Omicron antibody escape

A new study examined the neutralization of virus variants using three sets of antibodies: serum from individuals vaccinated or infected with earlier variants of the virus; concentrated human antibodies from plasma donors; and approved monoclonal antibodies.

16 Dec 2021

ACTG announces the launch of clinical trial to evaluate new CMV vaccine in adults

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the launch of A5355, a clinical trial studying a new cytomegalovirus (CMV) vaccine in adults with both HIV and CMV.

16 Dec 2021

Using fungal vaccine to train stem cells and enhance immune response to infections

The research group Immunology of Fungal Infections at the University of Valencia (UV) has investigated a fungal vaccine with which to train stem cells and hematopoietic progenitors (which produce all the cells of the blood and lifelong immune system) to improve the immune response to infections. The work has been published in the journal Frontiers in Immunology.

16 Dec 2021

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

The team observed that three doses of the BNT162b2 (Pfizer-BioNTech) mRNA vaccine are required to mount an effective antibody response against the Omicron variant.

16 Dec 2021

Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

A new study has used this assay to evaluate sera, obtained from 239 individuals vaccinated via any of the above-stated vaccines against SARS-CoV-2’s original strain, the Delta, and Omicron SARS-CoV-2 pseudoviruses.

16 Dec 2021

Omicron is more transmissible but may have milder symptoms for many people, expert says

If the first reports coming out of South Africa are correct, Omicron might be more transmissible than the current dominant Covid-19 strain, Delta, but cause less severe symptoms for many people. A leading expert says that, if the new strain does turn out to be milder for some people, that creates a new set of problems.

16 Dec 2021

T-cell immune response in previously infected and vaccinated individuals effective against SARS-CoV-2 Omicron variant

New findings illustrate that despite the continuous pattern of the ongoing evolution of SARS-CoV-2, it has not resulted in any significant accumulation of CD8+ T-cell escape mutations.

15 Dec 2021

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

New research optimizes methods for the in-planta expression of the recombinant protein corresponding to the Receptor Binding Domain (RBD) subunit of the surface-exposed Spike glycoprotein of SARS-CoV-2.

15 Dec 2021

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Researchers generated a set of computed structural models of the Omicron receptor-binding domain attached to its receptor angiotensin-converting enzyme.

15 Dec 2021

Risk of Guillain-Barré syndrome decreases after COVID-19 vaccination

A new study suggests that low GBS incidence in vaccinated patients compared to non-vaccinated people should encourage the active propagation of vaccination against SARS-CoV-2.

15 Dec 2021

How fast has the Omicron strain been spreading in South Africa?

Scientists have shown the exponential growth of the Omicron strain found in Gauteng. They reported the doubling time of this strain to be equal to 3.38 days by analyzing its growth from November 8 to December 5, 2021. Based on the mutation accumulation profile, researchers revealed that this strain began to diverge between October 28 and November 5, 2021.

15 Dec 2021

Driving up immunity at tumor site may help enhance immunotherapy treatments

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

14 Dec 2021

Immune Response News and Research

Researchers find muscle growth in some critically ill COVID-19 patients

University of Birmingham launches 5 new major studies focused on management of type 1 diabetes

Efficacy of NVX-CoV2373 in the US and Mexican adult population

Investigating potential cross-protection against SARS-CoV-2 after previous exposure to bovine coronavirus

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Analysis of the alteration of neutralizing titers with Omicron pseudovirus

Study provides a more effective treatment approach to preventing graft-versus-host-disease

New study demonstrates SARS-CoV-2 Omicron antibody escape

ACTG announces the launch of clinical trial to evaluate new CMV vaccine in adults

Using fungal vaccine to train stem cells and enhance immune response to infections

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

Experimental and computational synergy considered a promising approach in COVID-19 patients

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

Omicron is more transmissible but may have milder symptoms for many people, expert says

T-cell immune response in previously infected and vaccinated individuals effective against SARS-CoV-2 Omicron variant

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Risk of Guillain-Barré syndrome decreases after COVID-19 vaccination

How fast has the Omicron strain been spreading in South Africa?

Driving up immunity at tumor site may help enhance immunotherapy treatments

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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