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New study seeks to understand how colibactin causes cancer

For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered by their inability to isolate the compound.

15 Feb 2019

Researchers study animal venoms to identify new medicines for treating diseases

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

15 Feb 2019

Innovative new software could help prevent incidence of arrhythmia

Potentially lethal heart conditions may become easier to spot and may lead to improvements in prevention and treatment thanks to innovative new software that measures electrical activity in the organ.

14 Feb 2019

Researchers develop powerful new approach to improve maturation of miniature kidneys

In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, liver, intestine, and even the brain.

13 Feb 2019

Researchers provide insight into how breast tissue stiffening promotes cancer development

A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells.

13 Feb 2019

New PET imaging agent may help measure efficacy or failure of hormone therapy for breast cancer

Physicians may soon have a new way to measure the efficacy or failure of hormone therapy for breast cancer patients, according to new research published in the February issue of The Journal of Nuclear Medicine.

12 Feb 2019

New hydrogel-based muscles manipulate and stimulate biological tissue

Human tissues experience a variety of mechanical stimuli that can affect their ability to carry out their physiological functions, such as protecting organs from injury.

11 Feb 2019

Researchers find anti-microRNAs as potential new therapeutic target for type 2 diabetes

Researchers have shown that targeted silencing of microRNA-132, which is over-expressed in type 2 diabetes, can result in improved insulin secretion and reduced blood glucose in mice and increased insulin secretion in isolated human islet cells.

8 Feb 2019

Making the Most of Microdialysis for Neurotransmitter Analysis

Martin Eysberg provides an introduction to the ALEXYS Neurotransmitter Analyzer, an extremely precise UHPLC-EC detector for neurotransmitter analysis.

From Antec Scientific 6 Feb 2019

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form.

5 Feb 2019

Chemicals used to flavor e-cigs may impair lung function

Two chemicals widely used to flavor electronic cigarettes may be impairing the function of cilia in the human airway, according to a new study led by Harvard T.H. Chan School of Public Health.

1 Feb 2019

Cancer nanomedicine may accelerate metastasis, NUS study finds

Nanoparticles can be found in processed food (e.g. food additives), consumer products (e.g. sunscreen) and even in medicine. While these tiny particles could have large untapped potential and novel new applications, they may have unintended and harmful side effects, according to a recent study by researchers from the National University of Singapore.

1 Feb 2019

New research may help treat HIV patients without elevating risk for liver disease

As a raft of new treatments for HIV infection have come on the market in the past 20 years, AIDS patients got access to drugs that allowed them to live longer.

1 Feb 2019

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

SCYNEXIS, Inc., a biotechnology company delivering innovative therapies for difficult-to-treat and often life-threatening infections, today announced positive results from the first interim efficacy analysis of the ongoing FURI study.

1 Feb 2019

Computational model of the heart’s mitral valve enables customized care for patients

Engineers at The University of Texas at Austin have developed a new noninvasive technique for simulating repairs to the heart's mitral valve with levels of accuracy reliable enough for use in a clinical setting.

30 Jan 2019

New insight into anti-malaria drug

Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries. The effectiveness was investigated by the Chinese researcher Tu Youyou.

29 Jan 2019

Researchers identify why heart attack triggers arrhythmia in some people

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

29 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019

EU research project is studying the effect of endocrine disruptors on metabolism

January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved.

28 Jan 2019

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ions.

25 Jan 2019

in vivo News and Research

New study seeks to understand how colibactin causes cancer

Researchers study animal venoms to identify new medicines for treating diseases

Innovative new software could help prevent incidence of arrhythmia

Researchers develop powerful new approach to improve maturation of miniature kidneys

Researchers provide insight into how breast tissue stiffening promotes cancer development

New PET imaging agent may help measure efficacy or failure of hormone therapy for breast cancer

New hydrogel-based muscles manipulate and stimulate biological tissue

Researchers find anti-microRNAs as potential new therapeutic target for type 2 diabetes

Making the Most of Microdialysis for Neurotransmitter Analysis

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Chemicals used to flavor e-cigs may impair lung function

Cancer nanomedicine may accelerate metastasis, NUS study finds

New research may help treat HIV patients without elevating risk for liver disease

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

Computational model of the heart’s mitral valve enables customized care for patients

New insight into anti-malaria drug

Researchers identify why heart attack triggers arrhythmia in some people

New drug compounds show promise in treating acute myeloid leukemia

EU research project is studying the effect of endocrine disruptors on metabolism

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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