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Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.

11 Apr 2017

Scientists grow womb lining models that could shed light on early pregnancy events

Scientists from the University of Cambridge have grown miniature functional models of the womb lining in culture, representing a major step forwards in the study of early-stage pregnancy and conditions such as endometriosis.

11 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

The precise mechanism used by Legionella bacteria to escape the body's defences has been unpicked in intricate detail and is described for the first time in the journal eLife.

11 Apr 2017

Researchers map gene activity to reveal how the liver performs different functions

If you get up in the morning feeling energetic and clearheaded, you can thank your liver for manufacturing glucose before breakfast time. Among a host of other vital functions, it also clears our body of toxins and produces most of the carrier proteins in our blood.

11 Apr 2017

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell development.

10 Apr 2017

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research for the second time in 4 years, enabling the Institute to continue investigating the biology of normal human aging and age-related diseases.

10 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Miniature models of ‘womb lining’ could provide insights into early pregnancy and menstrual cycle

Scientists at the University of Cambridge have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture.

10 Apr 2017

High level of protein appears to diminish energy burning power of brown fat

Too much of a protein already associated with prostate cancer appears to also diminish the energy burning power of brown fat, scientists report.

10 Apr 2017

Research finding could offer new way to fight deadly pancreatic cancer

Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients.

10 Apr 2017

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis.

10 Apr 2017

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres - the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers.

10 Apr 2017

Scientists shed light on evolutionary arms race between CMV and immune system

Imaging CoE scientists have solved a 40-year old mystery and shed light on an evolutionary arms race played out between cytomegalovirus (CMV) and the immune system.

10 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

Programmed proteins could lead to inexpensive malaria vaccine

Despite decades of malaria research, the disease still afflicts hundreds of millions and kills around half a million people each year - most of them children in tropical regions.

10 Apr 2017

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

If all your life, you have been functioning best in the evening and night compared to the mornings, a gene mutation may be a reason.

10 Apr 2017

New model can simplify process of identifying optimal blends for drug cocktails

Drug cocktails such as those for treating cancer, like the alcoholic versions offered at the local bar, are best when the proper ingredients are mixed in the right proportions.

10 Apr 2017

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

Hematologist-oncologist Ahmad Samer Al-Homsi MD, MBA, will lead a new bone marrow transplantation program at NYU Langone's Perlmutter Cancer Center for treating blood-borne cancers, including leukemia, lymphoma and multiple myeloma, and potentially utilize transplantation as an adjunct to immunotherapy for solid tumors.

10 Apr 2017

Weather-forecast tool can help improve assessment and treatment of newborns with asphyxia

UT Southwestern Medical Center pediatric researchers have harnessed an analytical tool used to predict the weather to evaluate the effectiveness of therapies to reduce brain injury in newborns who suffer oxygen deprivation during birth.

10 Apr 2017

B Cell News and Research

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

Scientists grow womb lining models that could shed light on early pregnancy events

Scientists discover new role for autophagosomes in neurodegenerative diseases

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

Researchers map gene activity to reveal how the liver performs different functions

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

New study finds link between neural tube defects in infants and neurodegenerative diseases

Miniature models of ‘womb lining’ could provide insights into early pregnancy and menstrual cycle

High level of protein appears to diminish energy burning power of brown fat

Research finding could offer new way to fight deadly pancreatic cancer

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists shed light on evolutionary arms race between CMV and immune system

New research sheds light on movement of white blood cells to sites of infection

Programmed proteins could lead to inexpensive malaria vaccine

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

New model can simplify process of identifying optimal blends for drug cocktails

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

Weather-forecast tool can help improve assessment and treatment of newborns with asphyxia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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