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Sputum color guides antibiotic treatment in COPD

Withholding antibiotic treatment from hospitalized chronic obstructive lung disease patients with nonpurulent sputum does not negatively affect outcomes, a pilot study shows.

4 Dec 2012

Rethinking therapy decisions in autoimmune encephalopathy

Researchers say that diagnosis and management of encephalopathies may need to be rethought, as many patients who test negative for the relevant antibody still benefit from immunotherapy.

4 Dec 2012

Cognitive behavioral therapy for anxiety-related dizziness

Patients with chronic subjective dizziness that is related to anxiety may substantially benefit from a short course of cognitive behavioral therapy, report researchers.

4 Dec 2012

Data from OncoSec Medical clinical studies to be presented at DNA Vaccines 2012 Conference

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumor cancers, announced it will be presenting at the DNA Vaccines 2012 Conference at the Loews Coronado Bay Resort in San Diego, California. OncoSec is a Silver Sponsor of the conference.

4 Dec 2012

Kona Medical completes Series C financing

Kona Medical, Inc. today announced it has completed its Series C financing with the addition of $10 million in equity and debt, bringing total proceeds to $40 million.

4 Dec 2012

Linagliptin may reduce brain damage following stroke in type 2 diabetic patients

In a study in mice, scientists at Karolinska Institutet in Sweden have discovered a new potential therapy that may reduce brain damage following stroke in type 2 diabetic patients. The suggested drug is already approved for the treatment of type 2 diabetes. However, the scientists hope that this new results, presented in the scientific journal Diabetes, also opens up the possibility to decrease brain injury after stroke in other patient groups with a high stroke risk.

4 Dec 2012

Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms

A pilot study to determine the best hormonal treatment for infantile spasms (IS) that may lead to changes in prescribing practices for hormone therapy is being presented for the first time at the American Epilepsy Society's 66th Annual Meeting in San Diego California.

4 Dec 2012

Healthy eating prevents second heart attack, stroke or death in people with CVD

A heart-healthy diet rich in fruits, vegetables and fish significantly reduces the chance of a second heart attack and stroke in people with cardiovascular disease, McMaster University researchers have found.

4 Dec 2012

Sorin Group’s Mitroflow valve receives Japanese PMDA approval

Sorin Group, a global medical company and a leader in the treatment of cardiovascular diseases, announced today that it received the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) approval for the Mitroflow Aortic Pericardial Heart Valve.

4 Dec 2012

Many physicians misinformed about initial diagnosis and treatment of epilepsy

A survey of healthcare providers concerning the initial diagnosis and treatment of epilepsy has found significant misinformation held among physicians who see children who have seizures. Many physicians surveyed are misinformed about what constitutes intractable epilepsy, when to refer their pediatric patients for surgical evaluation, and what types of seizures may be amenable to surgical intervention.

4 Dec 2012

Combined oral contraceptives increase risk of blood clots in women with PCOS

Women with polycystic ovary syndrome (PCOS) who are taking combined oral contraceptives have a 2-fold risk of blood clots compared with women without the disorder who take contraceptives, states a study published in CMAJ (Canadian Medical Association Journal).

4 Dec 2012

Certain patients with prostate cancer may benefit from Provenge clinical trial

Select patients with advanced prostate cancer may benefit from a Georgia Health Sciences University Cancer Center clinical trial that looks to improve survival rates of the FDA-approved prostate cancer drug Provenge.

4 Dec 2012

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative.

3 Dec 2012

Chiropractic therapy gives parents something to smile about

Chiropractic manual therapy reduces crying behavior in infants with colic, study findings show.

3 Dec 2012

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

The addition of selumetinib to docetaxel therapy may boost the survival of patients with KRAS-mutant non-small-cell lung cancer, suggest study findings published in The Lancet Oncology.

3 Dec 2012

Innovative stem cell technique for heart tissue revealed

Researchers have found that stem cell cultures infused with growth factors could be used to repair damaged heart tissue without the threat of patient rejection.

3 Dec 2012

Structured hypertension care: VIPER lacks real bite

An intensive structured care program for hypertension management in primary care leads to some improvements in blood pressure control, results from the VIPER-BP trial show.

3 Dec 2012

Specific transporters could be exploited to deliver toxic substances into cancer cells

Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, the overexpression of specific transporters could be exploited to deliver toxic substances into cancer cells.

3 Dec 2012

Heart attack centres: an interview with Dr Sayan Sen

Heart attack networks are designed to facilitate the rapid transfer of heart attack patients to centres with facilities that allow the manual unblocking of the coronary artery with angioplasty.

3 Dec 2012

New laser surgical technique appears to be safe and effective in treating epilepsy

A developing new laser surgical technique for epilepsy appears to be safe and effective and reduces hospital stays to one or two days, according to two research reports presented today during the American Epilepsy Society 66th Annual Meting at the San Diego Convention Center.

3 Dec 2012