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Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT).

21 Jul 2023

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS.

21 Jul 2023

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

The ECOG-ACRIN Cancer Research Group has enrolled the first patient in a new treatment trial to evaluate the effectiveness of adding nilotinib to standard paclitaxel chemotherapy.

20 Jul 2023

UArizona researcher awarded $1.3 million to study lifestyle interventions in American Indian cancer patients

A University of Arizona Cancer Center researcher was awarded a $1.3 million grant from the National Cancer Institute to study the effectiveness of lifestyle interventions in American Indian patients with obesity-related solid tumor cancers who are preparing for surgery.

20 Jul 2023

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Study explores the effectiveness of caffeine consumption for headaches: trigger or remedy?

Caffeine has a dual role in headaches as it can induces or remediate them.

20 Jul 2023

Study shows how behavioral economics can help cancer patients quit smoking

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania found that cancer patients who continued to smoke after their diagnosis were significantly more likely to receive treatment for tobacco use when "nudges" to provide tobacco treatment were directed at clinicians through the electronic health record.

19 Jul 2023

Study provides new insights into how SARS-CoV-2 affects glucose metabolism

Research conducted at the University of São Paulo (USP) in Brazil shows that SARS-CoV-2, the virus that causes COVID-19, can infect liver cells (hepatocytes), stimulating glucose production and leading to a condition similar to diabetes (hyperglycemia) in hospitalized patients, even if their blood sugar level was normal before they were admitted to hospital.

19 Jul 2023

New method could make post-stroke motor rehabilitation more effective and affordable

The longest nerve in the human body starts in the brain and meanders its way down the neck and into the chest, where it splits into separate branches, winding its twisting tendrils to touch each internal organ.

19 Jul 2023

Targeted brain stimulation shows promise for treating TBI-related memory loss

Traumatic brain injury (TBI) has disabled 1 to 2% of the population, and one of their most common disabilities is problems with short-term memory. Electrical stimulation has emerged as a viable tool to improve brain function in people with other neurological disorders.

18 Jul 2023

IU researchers present groundbreaking findings at Alzheimer's conference

Researchers from Indiana University School of Medicine had a large presence and leadership role at the 2023 Alzheimer's Association International Conference in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

18 Jul 2023

Normothermic machine preservation shows promise in liver transplantation

A groundbreaking clinical trial comparing conventional low temperature storage of transplant donor livers with storage at physiological body temperature has revealed promising results for the evolution of liver transplantation.

17 Jul 2023

Donanemab may offer new hope for people with early Alzheimer's disease

The data reported today by Eli Lilly from the TRAILBLAZER-ALZ 2 clinical trial of donanemab in early symptomatic Alzheimer's disease demonstrate an important advancement in Alzheimer's research and treatment.

17 Jul 2023

Concussions do not affect IQ in children, study finds

The angst parents feel when their children sustain injuries is surely one of the universal conditions of parenthood. That anxiety is heightened greatly when those injuries involve concussions.

17 Jul 2023

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research directed by Johns Hopkins investigators.

17 Jul 2023

Intensive exercise slows the course of Parkinson's disease, study finds

Neuroscientists from the Faculty of Medicine of the Catholic University, Rome Campus, and the A. Gemelli IRCCS Polyclinic Foundation found that intensive exercise could slow the course of Parkinson's disease and described the biological mechanisms.

14 Jul 2023

Exercise can improve quality of life and reduce hospitalizations for dialysis patients

Patients who engage in light exercise while undergoing dialysis are physically fitter and are admitted to hospital less frequently than those who do not.

14 Jul 2023

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Brest cancer is the most common cancer in women. Among breast tumors that spread to other organs (develop metastasis), 70% belong to a variant, called luminal, whose cells are sensitive to the female sex hormones estrogen and progesterone. In fact, the tumor forms when these hormones order the cells to divide.

14 Jul 2023

CoRDS and Cure MITO join forces with C-Path to advance research for rare mitochondrial disorders

Critical Path Institute announced today that the Coordination of Rare Diseases based at Sanford Research (CoRDS), in partnership with Cure MITO, will contribute its mitochondrial disorders data from its international patient registry to the C-Path-managed Rare Disease Cures Accelerator-Data and Analytics Platform .

13 Jul 2023

Clinical Trial News and Research

Using bacteriophages to treat bladder infections

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

UArizona researcher awarded $1.3 million to study lifestyle interventions in American Indian cancer patients

Donanemab: A trailblazer for Alzheimer's disease treatment?

Study explores the effectiveness of caffeine consumption for headaches: trigger or remedy?

Study shows how behavioral economics can help cancer patients quit smoking

Study provides new insights into how SARS-CoV-2 affects glucose metabolism

New method could make post-stroke motor rehabilitation more effective and affordable

Targeted brain stimulation shows promise for treating TBI-related memory loss

IU researchers present groundbreaking findings at Alzheimer's conference

Normothermic machine preservation shows promise in liver transplantation

Donanemab may offer new hope for people with early Alzheimer's disease

Concussions do not affect IQ in children, study finds

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Intensive exercise slows the course of Parkinson's disease, study finds

Exercise can improve quality of life and reduce hospitalizations for dialysis patients

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

CoRDS and Cure MITO join forces with C-Path to advance research for rare mitochondrial disorders

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