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Huntington's disease impairs autophagy in older patients

Huntington's disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don't begin until middle adulthood.

28 Oct 2022

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

The malignant brain tumor type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumor cells resting and insensitive to radiation treatment.

28 Oct 2022

Research shows in real time how immune memory cells are stored in the bone marrow

Vaccines work their magic by effectively creating immune cells that are long lived, often for over decades.

28 Oct 2022

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus.

28 Oct 2022

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

All living cells harbor nuclei-;key biological structures that play an important role in information storage, retrieval, and duplication of genetic information.

28 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

Researchers find a switch to regulate the diabetes-causing gene

Researchers at the Centre for Genomic Regulation and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes.

27 Oct 2022

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

In a trial matching new treatments to cancer patients based on the genetic make-up of their tumors, 22% of the patients treated with the AKT inhibitor drug ipatasertib had their tumors shrink.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

First report of natural recombination of monkeypox virus genome

Researchers analyzed monkeypox virus sequences during the current 2022 outbreak to investigate whether MPXV is adapting for improved survival and viral transmission among humans.

27 Oct 2022

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Researchers assessed whether loss-of-function variants of type I interferon immunity genes are associated with life-threatening COVID-19.

27 Oct 2022

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

As part of an interdisciplinary project of the LOEWE Centre Frankfurt Cancer Institute (FCI), researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, and Goethe University Frankfurt have succeeded in identifying a new approach for the therapy of colorectal cancer.

27 Oct 2022

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

Researchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut could be responsible for triggering rheumatoid arthritis (RA) in people already at risk for the autoimmune disease.

26 Oct 2022

Genetic News and Research

Huntington's disease impairs autophagy in older patients

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

Research shows in real time how immune memory cells are stored in the bone marrow

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Yeast reveals a key mechanism in how genes are controlled

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

Ancient viral DNA in human genomes protects cells against present-day viruses

Rutgers physicians take newer approach in successfully treating a mysterious disease

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers find a switch to regulate the diabetes-causing gene

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

Discovery points to a new understanding of Stargardt disease progression

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

First report of natural recombination of monkeypox virus genome

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

Sequencing & Genomics: Elevating Science and Healthcare eBook

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Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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