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Investigational drug targeting the opioid system may help reduce symptoms of major depression

Two clinical trials of an investigational drug that targets the opioid system support its safety and effectiveness in reducing symptoms of major depression, when added to standard antidepressant treatment.

29 Oct 2018

New method increases virus production in cells to generate more vectors for gene transfer

Researchers at Tokyo Medical and Dental University have established a method to increase the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes into cells

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

New approach may lead to protective vaccines for immunocompromised patients

A study led by Som Nanjappa at the University of Illinois College of Veterinary Medicine identifies a cellular target that may improve efficacy in vaccines designed to protect immunocompromised individuals from potentially deadly opportunistic infections.

26 Oct 2018

STIs being diagnosed in young adults every four minutes in the UK

According to latest statistics, one young person is diagnosed with a sexually-transmitted infection (STI) every four minutes in England.

26 Oct 2018

HPTN 075 study shows high risk of HIV infection among MSM and TGW in sub-Saharan Africa

Researchers from the HIV Prevention Trials Network today presented results from the HPTN 075 Study at the HIV Research for Prevention conference in Madrid, Spain.

24 Oct 2018

Global HIV Vaccine Enterprise launches strategy to accelerate development of effective HIV vaccine

The Global HIV Vaccine Enterprise, hosted by the International AIDS Society, has launched a five-year strategy to accelerate the development of an effective vaccine to prevent HIV infection.

23 Oct 2018

New diagnostic platform simultaneously screens for all known pathogenic bacteria

Scientists at the Center for Infection and Immunity in the Columbia University Mailman School of Public Health have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria as well as markers for virulence and antibiotic resistance.

23 Oct 2018

Primary care doctors ‘not doing enough’ to curb STDs

Julie Lopez, 21, has been tested regularly for sexually transmitted diseases since she was a teenager. But when Lopez first asked her primary care doctor about screening, he reacted with surprise, she said.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

HIV-infected Hispanics at higher risk of developing HPV-related cancers, finds study

A new study reveals that Hispanic HIV-infected adults in the United States are at a higher risk of developing cancers caused by the human papillomavirus than Hispanics from the general population.

22 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Researchers awarded grant to advance testing of experimental heroin vaccine

Researchers at the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research and SUNY Upstate Medical University in Syracuse, N.Y., have been awarded a grant to advance an experimental heroin vaccine through Phase I/IIa clinical trials to assess both its safety and its efficacy against a morphine challenge.

17 Oct 2018

HIV-infected infants more likely to acquire congenital cytomegalovirus infection

Infants born to HIV-positive mothers had high rates of congenital cytomegalovirus, or CMV. Infants who also were infected before birth by the virus that causes AIDS were especially prone to CMV infection.

16 Oct 2018

Survey results highlight the need for better communication between patients and HCPs about bacterial vaginosis

According to an online survey, although healthcare providers report sharing crucial information on bacterial vaginosis with patients, the associated risks of the condition remain a mystery to many women, indicating a significant disconnect.

16 Oct 2018

UVA partners with health systems in AVIA network’s Medicaid Transformation Project

University of Virginia Health System is partnering with more than 20 other health systems in the AVIA network's Medicaid Transformation Project to develop financially sustainable solutions to improving the health of the nearly 75 million Americans who receive Medicaid.

15 Oct 2018

Global health innovation system fails to deliver affordable treatments to patients, says report

NHS patients are being let down by a global health innovation system which fails to deliver the treatments they need at prices that government can afford, according to a new report led by Professor Mariana Mazzucato, Director of the UCL Institute for Innovation and Public Purpose, in collaboration with STOPAIDS, Global Justice Now and Just Treatment.

15 Oct 2018

Researchers identify effective ketamine dosage levels for patients with treatment-resistant depression

A study led by Massachusetts General Hospital investigators identifies two subanesthetic dosage levels of the anesthetic drug ketamine that appear to provide significant symptom relief to patients with treatment-resistant depression.

11 Oct 2018

Researchers develop new techniques for faster detection of Lyme disease bacteria

Researchers have developed techniques to detect Lyme disease bacteria weeks sooner than current tests, allowing patients to start treatment earlier.

11 Oct 2018

HIV News and Research

Investigational drug targeting the opioid system may help reduce symptoms of major depression

New method increases virus production in cells to generate more vectors for gene transfer

Getting right level of leptin may help protect cardiovascular health

New approach may lead to protective vaccines for immunocompromised patients

STIs being diagnosed in young adults every four minutes in the UK

HPTN 075 study shows high risk of HIV infection among MSM and TGW in sub-Saharan Africa

Global HIV Vaccine Enterprise launches strategy to accelerate development of effective HIV vaccine

New diagnostic platform simultaneously screens for all known pathogenic bacteria

Primary care doctors ‘not doing enough’ to curb STDs

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

HIV-infected Hispanics at higher risk of developing HPV-related cancers, finds study

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Researchers awarded grant to advance testing of experimental heroin vaccine

HIV-infected infants more likely to acquire congenital cytomegalovirus infection

Survey results highlight the need for better communication between patients and HCPs about bacterial vaginosis

UVA partners with health systems in AVIA network’s Medicaid Transformation Project

Global health innovation system fails to deliver affordable treatments to patients, says report

Researchers identify effective ketamine dosage levels for patients with treatment-resistant depression

Researchers develop new techniques for faster detection of Lyme disease bacteria

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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