Growth Factor News and Research

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New therapeutic approaches to castrate resistant prostate cancer

Today Dr. Martin Gleave of the Vancouver Prostate Centre in Canada gave a lecture about new approaches to treat castrate-resistant prostate cancer (CRCP) during the 24 th Annual Congress of the European Association of Urology in Stockholm, Sweden.

22 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

Discovery of master switch that might prevent cancer cells from metastasizing

Researchers at the University of Pennsylvania School of Medicine have identified a master switch that might prevent cancer cells from metastasizing from a primary tumor to other organs.

16 Mar 2009

Combo therapy restores T cell numbers in HIV-infected individuals

White blood cells known as CD4+ T cells are the main target of HIV.

16 Mar 2009

Genetic mechanism in mole rats can be targeted in cancer research

"When we understand how the subterranean mole rat developed these mechanisms for survival, we may be able to understand why they are so destructive in humans," Prof. Aaron Avivi of the University of Haifa said.

15 Mar 2009

New measure for the malignancy of melanoma

Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen.

12 Mar 2009

Discovery of cellular pathway that prevents cancer response to diet restriction

Whitehead Institute researchers have pinpointed a cellular pathway that determines whether cancerous tumors respond to dietary restriction during their development.

11 Mar 2009

Cell pathway on overdrive prevents cancer response to dietary restriction

Whitehead Institute researchers have pinpointed a cellular pathway that determines whether cancerous tumors respond to dietary restriction during their development.

11 Mar 2009

Blood test predicts chance of frontal lobe dementia

Frontal lobe dementia (Frontotemporal Dementia, FTD) strikes people at an earlier age. After Alzheimer's disease, FTD is the form of dementia that occurs most frequently in patients younger than 65.

8 Mar 2009

Bottom up assembly of cells into 3-D microtissues

Scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory can now control how cells connect with one another in vitro and assemble themselves into three-dimensional, multicellular microtissues.

5 Mar 2009

Angiogenesis inhibitors, study points to limitations, solutions

A new generation of cancer drugs designed to starve tumors of their blood supply - called "angiogenesis inhibitors"-succeeds at first, but then promotes more invasive cancer growth-sometimes with a higher incidence of metastases, according to a new study in animals.

2 Mar 2009

Discovery provides better understanding of craniosynostosis

Craniosynostosis develops in the womb and affects one in every 2500 live births. Bones in the skulls and face of sufferers fuse together prematurely causing a range of distressing developmental problems.

2 Mar 2009

Proepithelin encourages cell growth and migration in prostate cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells.

26 Feb 2009

A second MND gene mutation in one year signifies rapid research progress

A collaborative research project involving Professor Christopher Shaw of the Institute of Psychiatry, King's College London (KCL), Dr Tom Kwiatkowski at Massachusetts General Hospital (MGH) and Professor Robert H Brown at University of Massachusetts, has revealed that mutations in a gene called FUS (fused in sarcoma) cause familial Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).

26 Feb 2009

New imaging techniques let scientists see biomolecules more clearly

Scientists have always wanted to take a closer look at biological systems and materials. From the magnifying glass to the electron microscope, they have developed increasingly sophisticated imaging devices.

23 Feb 2009

Leptin shows potential for type 1 diabetes

Terminally ill rodents with type 1 diabetes have been restored to full health with a single injection of a substance other than insulin by UT Southwestern Medical Center scientists.

16 Feb 2009

Molecules self-assemble to provide new therapeutic treatments

Researchers in the laboratory of Samuel I. Stupp at Northwestern University have an interesting approach for tackling some major health problems: gather raw materials and then let them self-assemble into structures that can address a multitude of medical needs.

16 Feb 2009

Discovery of potential treatment for Rett syndrome

A molecule that promotes brain development could serve as a possible treatment for Rett syndrome, the most common form of autism in girls, according to researchers at MIT's Picower Institute for Learning and Memory and the Whitehead Institute for Biomedical Research.

9 Feb 2009

Hair follicle stem cells may be key to organ regeneration

Most people consider hair as a purely cosmetic part of their lives. To others, it may help uncover one of nature's best-kept secrets: the body's ability to regenerate organs.

8 Feb 2009

Brain-derived neurotrophic factor protects key brain cells in Alzheimer's models

Memory loss, cognitive impairment, brain cell degeneration and cell death were prevented or reversed in several animal models after treatment with a naturally occurring protein called brain-derived neurotrophic factor (BDNF).

8 Feb 2009