Immune Response News and Research

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SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

Researchers have been investigating the immune response in previously infected healthcare workers after they receive these vaccines.

13 Dec 2021

Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

Effectiveness of COVID-19 booster vaccination strategies in partially vaccinated populations

Study reveals that the most beneficial vaccination strategy is to distribute all available doses of COVID-19 vaccines predominantly for primary vaccinations and the remaining doses for boosters.

12 Dec 2021

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

A team of researchers recently developed a statistical modeling method known as multiple-layer crosstalk (MLCrosstalk).

12 Dec 2021

Even if SARS-CoV-2 Omicron evades antibodies, immunity still exists

Researchers determined antibody-mediated neutralization efficacy against the authentic SARS-CoV-2 Omicron variant.

12 Dec 2021

Health experts recommend the increase in UK COVID-19 alert level from Level 3 to Level 4

Following advice from the UK Health Security Agency and in the light of the rapid increase in Omicron cases, the UK Chief Medical Officers and NHS England National Medical Director have recommended to ministers that the UK COVID-19 alert level should increase from Level 3 to Level 4.

12 Dec 2021

Formula 1's biggest stars urge all fans to get their COVID-19 vaccine

Formula 1's biggest stars have backed the UK's vaccine rollout and urged all fans to get their jab as soon as possible this winter in a new film out today (Saturday 11 December).

12 Dec 2021

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

The emergence of COVID-19 variants such as delta and omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.

11 Dec 2021

UCLA research points the way towards a longer-lasting COVID vaccine

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.

11 Dec 2021

COVID-19 booster program accelerated, 22 million people in the UK have received top-up jabs

More than 22 million people in the UK have now received a COVID-19 top up jab, as the booster programme is accelerated this winter.

10 Dec 2021

Study finds mutational changes in Omicron variant likely increase transmissibility

A new study presented evidence for a large number of mutational changes in the Omicron variant which will likely increase its transmissibility and significantly decrease the neutralization capacity of monoclonal antibodies, leading to a decline in vaccine efficacy.

10 Dec 2021

Impact of mRNA-1273 vaccination during early pregnancy

Researchers from Yale University School of Medicine found that vaccination during the first trimester does not produce congenital disabilities or size abnormalities.

10 Dec 2021

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Potential association between senescence and aging in COVID-19

A review published in Cells discussed characteristics of cellular senescence and its potential role in COVID-19.

9 Dec 2021

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Researchers have developed Nanocovax, a COVID-19 subunit vaccine based on recombinant protein technology to produce the extracellular (soluble) portion of the S protein of SARS-CoV-2.

9 Dec 2021

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

New research from the University of East Anglia and Quadram Institute reveals how our immune cells use the body’s fat stores to fight infection.

9 Dec 2021

UVA researchers uncover common link between lupus and macular degeneration

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

9 Dec 2021

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

The N-terminal domain has a fold that can bind sugar, and new research led by Jonathan Lees from Oxford Brookes University found the sugar-binding pockets near the N-terminal domain help to increase viral infectivity. Furthermore, the findings show that the SARS-CoV-2 sugar-binding pockets are evolving with added loops observed in the pockets of new variants.

9 Dec 2021

Immune Response News and Research

SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

Genetic-code expansion technique to potentially create next-generation vaccine candidate

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

Effectiveness of COVID-19 booster vaccination strategies in partially vaccinated populations

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

Even if SARS-CoV-2 Omicron evades antibodies, immunity still exists

Health experts recommend the increase in UK COVID-19 alert level from Level 3 to Level 4

Formula 1's biggest stars urge all fans to get their COVID-19 vaccine

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

UCLA research points the way towards a longer-lasting COVID vaccine

COVID-19 booster program accelerated, 22 million people in the UK have received top-up jabs

Study finds mutational changes in Omicron variant likely increase transmissibility

Impact of mRNA-1273 vaccination during early pregnancy

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Potential association between senescence and aging in COVID-19

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

UVA researchers uncover common link between lupus and macular degeneration

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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