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New birth-control strategy for mosquitoes can combat malaria

Using information about the unique mating practices of the male malaria mosquito ― which, unlike any other insect, inserts a plug to seal its sperm inside the female ― scientists are zeroing in on a birth-control drug for Anopheles mosquitoes, deadly carriers of the disease that threatens 3 billion people, has infected more than 215 million and kills 655,000 annually.

20 Aug 2012

Scientists demonstrate automated worm sorter for biological research

Research into the genetic factors behind certain disease mechanisms, illness progression and response to new drugs is frequently carried out using tiny multi-cellular animals such as nematodes, fruit flies or zebra fish.

20 Aug 2012

ACS National Meeting & Exposition focuses on DNA wires and their potential use in identifying diseases

In a discovery that defies the popular meaning of the word "wire," scientists have found that Mother Nature uses DNA as a wire to detect the constantly occurring genetic damage and mistakes that ― if left unrepaired ― can result in diseases like cancer and underpin the physical and mental decline of aging.

20 Aug 2012

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

Using advanced computer simulations, University of Utah College of Pharmacy researchers have produced moving images of a protein complex that is an important target for anti-cancer drugs.

18 Aug 2012

Total cholesterol test can identify patients at increased risk of heart disease

Researchers in India have developed a total cholesterol test that uses a digital camera to take a snapshot of the back of the patient's hand rather than a blood sample. The image obtained is cropped and compared with images in a database for known cholesterol levels.

18 Aug 2012

Safety net hospitals prepare for changes from health law; Patients hesitant to challenge doctors

Safety-net hospitals – which often provide care to low-income and uninsured populations – are facing reduced federal and state support for uncompensated care under the Affordable Care Act. However, this study points out that 23 million people will remain uninsured and continue to need care from the hospitals.

18 Aug 2012

Mullite can reduce pollution produced by diesel vehicles

Engineers at a company co-founded by a University of Texas at Dallas professor have identified a material that can reduce the pollution produced by vehicles that run on diesel fuel.

17 Aug 2012

Affordable Care Act: an interview with Val J. Halamandaris, President of the National Association for Home Care & Hospice (NAHC)

The intent of the Affordable Care Act (ACA) is to provide all Americans with medical insurance. Thirty-five million additional people will be covered, in part by government premiums and in part by making it easier for them to buy their own insurance.

17 Aug 2012

In face of global economic recession, developing world needs low-tech health innovations

"The developing world needs support for low-tech health innovations that do not compromise on effectiveness," journalist Priya Shetty writes in this SciDev.Net opinion piece, adding that, against the backdrop of global economic recession and shrinking research and development (R&D) budgets in many developing countries, "a new movement of 'frugal science' is taking hold, in which researchers are hunting for the most cost-effective health technologies for developing countries."

17 Aug 2012

Viewpoints: Public seeks better campaigns but politicians use 'schoolyard rules;' GOP's Medicare 'flip-flops'

Political ads often stretch facts to the breaking point, but the people who create them usually feel constrained to back up their claims by citing sources - at least enough to keep neutral fact-checkers from exposing their work as fiction. Not so in this year's presidential campaign. There's no nice way to say this: President Obama and Republican challenger Mitt Romney are both condoning deliberate falsehoods.

17 Aug 2012

New DNA sequencing tests improve ability to analyze genetic disorders

Scientists at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School (UMDNJ-NJMS) have developed new DNA sequencing tests that hold significant promise for decreasing costs associated with diagnosing cancer and hereditary diseases, including cysticfibrosis.

17 Aug 2012

Rhomboid enzymes and malaria treatment: an interview with Sinisa Urban

Rhomboid enzymes live in the cell’s membrane where their job is to cut the anchors of proteins, which releases the target proteins from the membrane.

16 Aug 2012

Febrile seizures increase hippocampal injury risk

Children with febrile status epilepticus are at risk for hippocampal injury and show abnormalities in the development of this brain area, show findings from a prospective multicenter study.

16 Aug 2012

Radiosensitivity molecular signature can lead to better radiation therapy decisions for breast cancer

Researchers at Moffitt Cancer Center, working with colleagues in Sweden, the Netherlands and Puerto Rico, have validated a radiosensitivity molecular signature that can lead to better radiation therapy decisions for treating patients with breast cancer.

16 Aug 2012

Gates looks to develop 'next-generation toilets' for developing world

Bill Gates, co-chair of the Bill & Melinda Gates Foundation, on Tuesday "announced the winners of the Reinvent the Toilet Challenge -- an effort to develop 'next-generation' toilets that will deliver safe and sustainable sanitation to the 2.5 billion people worldwide who don't have it," according to a foundation press release.

16 Aug 2012

India launches new laboratory for HIV vaccine research in collaboration with IAVI

India on Monday "opened a $12 million, government-backed laboratory whose mission is to create a new vaccine against HIV," Science Insider reports.

16 Aug 2012

Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Malignant mesothelioma is a rare tumor of the pleura which is the lining of the inside of the chest wall. It is highly linked with asbestos exposure.

16 Aug 2012

Medicago, IDRI receive FDA approval to commence Phase 1 H5N1 vaccine trial

The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), announce that they have been cleared by the U.S. Food and Drug Administration (FDA) to initiate a Phase 1 clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.

16 Aug 2012

Article describes novel technique to study interactions between HIV-1 and P. falciparum

The World Health Organization estimates that in 2011 there were 216 million cases of malaria and 34.2 million people living with HIV. These diseases particularly afflict sub-Saharan Africa, where large incidence of co-infection result in high mortality rates. Yet, in spite of this global pandemic, interactions between the parasite that causes malaria, Plasmodium falciparum, and HIV-1 are poorly understood.

16 Aug 2012

RNA-delivering nanoparticles allow rapid screening of new drug targets in mice

By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly impossible to test them all in a timely fashion.

16 Aug 2012

Technology News and Research

New birth-control strategy for mosquitoes can combat malaria

Scientists demonstrate automated worm sorter for biological research

ACS National Meeting & Exposition focuses on DNA wires and their potential use in identifying diseases

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

Total cholesterol test can identify patients at increased risk of heart disease

Safety net hospitals prepare for changes from health law; Patients hesitant to challenge doctors

Mullite can reduce pollution produced by diesel vehicles

Affordable Care Act: an interview with Val J. Halamandaris, President of the National Association for Home Care & Hospice (NAHC)

In face of global economic recession, developing world needs low-tech health innovations

Viewpoints: Public seeks better campaigns but politicians use 'schoolyard rules;' GOP's Medicare 'flip-flops'

New DNA sequencing tests improve ability to analyze genetic disorders

Rhomboid enzymes and malaria treatment: an interview with Sinisa Urban

Febrile seizures increase hippocampal injury risk

Radiosensitivity molecular signature can lead to better radiation therapy decisions for breast cancer

Gates looks to develop 'next-generation toilets' for developing world

India launches new laboratory for HIV vaccine research in collaboration with IAVI

Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Medicago, IDRI receive FDA approval to commence Phase 1 H5N1 vaccine trial

Article describes novel technique to study interactions between HIV-1 and P. falciparum

RNA-delivering nanoparticles allow rapid screening of new drug targets in mice

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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