Therapy News and Research

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MED1 plays a central role in mediating tamoxifen resistance in breast cancer

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease.

3 Nov 2012

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say.

3 Nov 2012

Viewpoints: Romney, Obama offer their 'visions for America;' One liberal wary of Mass. effort on assisted suicide

Change is an America where we reduce our deficit by cutting spending where we can, and asking the wealthiest Americans to go back to the income tax rates they paid when Bill Clinton was president. I've worked with Republicans to cut a trillion dollars of spending, and I'll do more. I'll work with anyone of any party to move this country forward. But I won't agree to eliminate health insurance for millions of poor, elderly, or disabled on Medicaid, or turn Medicare into a voucher just to pay for another millionaire's tax cut.

3 Nov 2012

Men with prostate cancer can benefit from active surveillance

With active surveillance many men with prostate cancer could dispense with radiation treatment and surgery, and thus avoid adverse effects such as incontinence and impotence. This is the outcome of a study of almost 1,000 men diagnosed with prostate cancer conducted at Sahlgrenska Academy, University of Gothenburg, Sweden.

3 Nov 2012

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

The U.S. Food and Drug Administration today expanded the approved use of Xarelto (rivaroxaban) to include treating deep vein thrombosis (DVT) or pulmonary embolism (PE), and to reduce the risk of recurrent DVT and PE following initial treatment.

3 Nov 2012

Studies provide new information on diet and blood pressure in kidney disease patients

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on diet and blood pressure in kidney disease patients.

3 Nov 2012

AeriSeal System appears to be effective in treating emphysema

Researchers at the University of Alabama at Birmingham injected a foam sealant into the lungs of a former smoker on Oct. 29, 2012, to treat his worsening emphysema. He was the first patient in the United States treated in a late-stage clinical trial of the AeriSeal System.

3 Nov 2012

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

A Medicare rule that blocks thousands of nursing home residents from receiving simultaneous reimbursement for hospice and skilled nursing facility care at the end of life may result in those residents receiving more aggressive treatment and hospitalization, according a new analysis.

3 Nov 2012

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD).

3 Nov 2012

Near-complete blood flow restoration necessary to preserve neurological function following stroke

Two Rhode Island Hospital researchers recently found that restoring near-complete blood flow to the brain is necessary to restore or preserve neurological function following stroke. Seems like a no-brainer, right? Yet until their research was complete, many physicians and researchers believed that partial blood-flow restoration was good enough. Not anymore.

3 Nov 2012

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen.

From The University of Manchester 3 Nov 2012

Radiosurgery alone can achieve local control of brain metastases

Radiosurgery to the surgical cavity without whole-brain radiotherapy achieves good rates of local control in patients with brain cancer metastases, a study has shown.

2 Nov 2012

$Denosumab gives FREEDOM to heal fractures$

Denosumab gives FREEDOM to heal fractures

Results from the FREEDOM trial indicate that fracture healing is not impaired in women with osteoporosis who use the antiresorptive therapy denosumab.

2 Nov 2012

TD-1211 may relieve opioid-induced constipation

TD-1211 – an inhibitor of the mµ-opioid receptor – alleviates chronic noncancer-related constipation in patients receiving opioid therapy, without affecting pain relief, show the results of a parallel-group study.

2 Nov 2012

Advanced breast cancer that has spread to the brain could be treated with drug combination

The sizeable and increasing proportion of women with advanced breast cancer whose disease has spread to the brain could be effectively treated systemically with a combination of two drugs, sparing them the debilitating neurological side effects of whole brain radiotherapy (WBRT), suggests new research published Online First in The Lancet Oncology.

2 Nov 2012

Hurricane Sandy’s impact on home care: an interview with Joanne Cunningham

Home care agencies, like all health providers, have only a matter of days to prepare for a specific weather event like Hurricane Sandy. However, disaster preparedness planning is a core function of home care service providers.

2 Nov 2012

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.

2 Nov 2012

CD22 protein could prove to be important new target for anti-cancer therapy

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time.

2 Nov 2012

Soy products do not prevent onset of vasomotor symptoms in women

A team of investigators led by UC Davis found that eating soy products such as soy milk and tofu did not prevent the onset of hot flashes and night sweats as women entered menopause.

2 Nov 2012

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Affymax, Inc. and Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) today announced the presentation of post-hoc sub-group analyses of the EMERALD Phase 3 studies that evaluated OMONTYS (peginesatide) Injection, an erythropoiesis-stimulating agent (ESA), for the treatment of anemia due to chronic kidney disease (CKD) in adult dialysis patients.

2 Nov 2012

Therapy News and Research

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

Viewpoints: Romney, Obama offer their 'visions for America;' One liberal wary of Mass. effort on assisted suicide

Men with prostate cancer can benefit from active surveillance

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

Studies provide new information on diet and blood pressure in kidney disease patients

AeriSeal System appears to be effective in treating emphysema

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

Near-complete blood flow restoration necessary to preserve neurological function following stroke

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

Radiosurgery alone can achieve local control of brain metastases

Denosumab gives FREEDOM to heal fractures

TD-1211 may relieve opioid-induced constipation

Advanced breast cancer that has spread to the brain could be treated with drug combination

Hurricane Sandy’s impact on home care: an interview with Joanne Cunningham

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

CD22 protein could prove to be important new target for anti-cancer therapy

Soy products do not prevent onset of vasomotor symptoms in women

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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