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Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative.

3 Dec 2012

Chiropractic therapy gives parents something to smile about

Chiropractic manual therapy reduces crying behavior in infants with colic, study findings show.

3 Dec 2012

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

The addition of selumetinib to docetaxel therapy may boost the survival of patients with KRAS-mutant non-small-cell lung cancer, suggest study findings published in The Lancet Oncology.

3 Dec 2012

Innovative stem cell technique for heart tissue revealed

Researchers have found that stem cell cultures infused with growth factors could be used to repair damaged heart tissue without the threat of patient rejection.

3 Dec 2012

Structured hypertension care: VIPER lacks real bite

An intensive structured care program for hypertension management in primary care leads to some improvements in blood pressure control, results from the VIPER-BP trial show.

3 Dec 2012

Specific transporters could be exploited to deliver toxic substances into cancer cells

Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, the overexpression of specific transporters could be exploited to deliver toxic substances into cancer cells.

3 Dec 2012

Heart attack centres: an interview with Dr Sayan Sen

Heart attack networks are designed to facilitate the rapid transfer of heart attack patients to centres with facilities that allow the manual unblocking of the coronary artery with angioplasty.

3 Dec 2012

New laser surgical technique appears to be safe and effective in treating epilepsy

A developing new laser surgical technique for epilepsy appears to be safe and effective and reduces hospital stays to one or two days, according to two research reports presented today during the American Epilepsy Society 66th Annual Meting at the San Diego Convention Center.

3 Dec 2012

Long-term hippocampal DBS effectively reduces seizures in experimental models

The results of the first reported study of deep brain stimulation (DBS) in an animal model for temporal lobe epilepsy (TLE) presented today at the American Epilepsy Society (AES) 66th Annual Meeting suggests that DBS may have potential as therapy for this common and often difficult to treat form of epilepsy.

2 Dec 2012

Collaborative care significantly improves depression and anxiety outcomes

Collaborative care, a model that involves multiple clinicians working with a patient, significantly improves depression and anxiety outcomes compared to standard primary care treatment for up to two years, finds a new review by The Cochrane Library.

1 Dec 2012

Study to discover how service members and veterans with SCI reintegrate into society

Record numbers of soldiers are returning from Iraq and Afghanistan with serious spinal cord injuries (SCI). Medical advancements can help heal their physical wounds, but little is known about how these veterans re-engage with their communities and rebuild meaningful lives. "How do they transition back to family and community life? How do they adjust to their physical impairments? And how do they reconfigure their homes, their work and their lives?" asked Cathy Lysack, professor of occupational therapy and gerontology at Wayne State University.

1 Dec 2012

Epidural steroid injections for back pain increase risk of bone loss in postmenopausal women

Postmenopausal women suffered significant bone density loss in their hip after they were treated with an epidural steroid injection for back pain relief, according to a Henry Ford Hospital study

1 Dec 2012

Mistletoe extract plays a vital role in treating colon cancer

Mistletoe has become an important symbol of Christmas but it also has the potential to play a vital role as an alternative therapy for sufferers of colon cancer.

30 Nov 2012

Delaying treatment affects mortality rates among women with breast cancer

Results from a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) show women who wait more than 60 days to begin treatment for advanced breast cancer face significantly higher risks of dying than women who start therapy shortly after diagnosis.

30 Nov 2012

Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma

Huntsman Cancer Institute researchers Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard treatments for chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic lymphoma.

30 Nov 2012

Special issue of Disease Markers explores ASD genetics and biomarker development

Autism spectrum disorders (ASD) are neurodevelopmental disorders typically characterized by difficulties in social interactions and delayed or abnormal language development. Although ASD reportedly affects 1 in 88 people in the United States, to date there have been no distinctive biomarkers to diagnose the disease.

30 Nov 2012

Sucampo receives supplement approval from FDA for AMITIZA

Sucampo Pharmaceuticals, Inc. today announced that the Company received a supplement approval from the U.S. Food and Drug Administration (FDA) that removes pregnancy "warnings and precautions" and clarifies information regarding the use of AMITIZA (lubiprostone) by pregnant and/or nursing women. In addition, the FDA expanded the labeling text of the Mechanism of Action section in the prescribing information for AMITIZA.

30 Nov 2012

Respiratory physical therapy before cardiac surgery may reduce serious pulmonary complications

Patients who practice respiratory physical therapy exercises before elective cardiac surgery may reduce serious pulmonary complications later, finds a new evidence review from The Cochrane Library.

30 Nov 2012

Rural cancer survivors more likely to have poor health outcomes

Cancer survivors who live in rural areas are more likely to say they are in poor health than those who live in urban areas, according to a study in the journal Cancer. They are also more likely to have other health disorders, more psychological distress, and be unemployed due to health reasons than city dwellers.

30 Nov 2012

Medically unexplained symptoms cause relevant annual excess costs in health care

This study highlights that medically unexplained symptoms cause relevant annual excess costs in health care that are comparable to mental health problems like depression or anxiety disorders and which may be reduced by interventions targeting physicians as well as patients. More extensive research on indirect costs and cost-effectiveness is needed.

30 Nov 2012

Therapy News and Research

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Chiropractic therapy gives parents something to smile about

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

Innovative stem cell technique for heart tissue revealed

Structured hypertension care: VIPER lacks real bite

Specific transporters could be exploited to deliver toxic substances into cancer cells

Heart attack centres: an interview with Dr Sayan Sen

New laser surgical technique appears to be safe and effective in treating epilepsy

Long-term hippocampal DBS effectively reduces seizures in experimental models

Collaborative care significantly improves depression and anxiety outcomes

Study to discover how service members and veterans with SCI reintegrate into society

Epidural steroid injections for back pain increase risk of bone loss in postmenopausal women

Mistletoe extract plays a vital role in treating colon cancer

Delaying treatment affects mortality rates among women with breast cancer

Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma

Special issue of Disease Markers explores ASD genetics and biomarker development

Sucampo receives supplement approval from FDA for AMITIZA

Respiratory physical therapy before cardiac surgery may reduce serious pulmonary complications

Rural cancer survivors more likely to have poor health outcomes

Medically unexplained symptoms cause relevant annual excess costs in health care

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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