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Better understanding of membrane fusion

Cells constantly swap cargo bound in vesicles, miniscule membrane-enclosed packages of proteins and other chemicals. Before the swap can take place, the vesicle membrane must fuse with another membrane, creating channels packages can pass through.

18 Apr 2007

Breakthrough in photoswitchable fluorescent protein science

University of Oregon scientists have identified molecular features that determine the light-emitting ability green fluorescent proteins, and by strategically inserting a single oxygen atom they were able to keep the lights turned off for up to 65 hours.

11 Apr 2007

Scientists at Johns Hopkins discover Solitary protein

Working with fruit flies, scientists at Johns Hopkins have discovered a protein required for two neighboring cells to fuse and become one "super cell."

11 Apr 2007

Bacterial endosymbionts are essential for the reproduction of a fungus

Endosymbiotic relationships, in which one organism lives within another, are striking examples of mutualism, and can often significantly shape the biology of the participant species.

7 Apr 2007

UT Metroplex institutions to collaborate on biomedical research

Researchers from the three University of Texas campuses in the Dallas-Fort Worth metropolitan area are combining their expertise in biomedical science, engineering and physical sciences on projects aimed at solving real-world medical problems.

5 Apr 2007

Handheld instrument assesses dental disease in minutes

Who would have guessed that when the Star Trek medical diagnostic tool known as the tricorder makes its appearance in real life, the first user might be . . . your dentist.

5 Apr 2007

Scientists take a close look at early events in immune response

A Sandia National Laboratories research team led by Anup Singh is taking a new approach to studying how immune cells respond to pathogens in the first few minutes and hours of exposure.

4 Apr 2007

Glimpse into early brain development shows how nerve cells move into position

Tucked into the lower, rear portion of the brain, the cerebellum plays key roles in motor learning, motor memory and sensory perception. It's also where the majority of metastatic childhood brain tumors are located. Yet scientists still know very little about its early growth.

29 Mar 2007

First time observing real-time molecular interplay within ribosome

The ribosome is a kind of factory for protein in the cell, and as such has long been a prime target for drug discovery. Now, a technological advance by a team at Weill Cornell Medical College is poised to revolutionize research in the field.

21 Mar 2007

Unlocking the mystery of skin renewal

Everyday we shed the outermost layer of our skin and replace it from within with new skin cells. Scientists from Cambridge have looked at the way that skin is renewed.

4 Mar 2007

Link between growth of blood vessels critical to spread of cancer and copper in our bodies

Growing new blood vessels from existing ones - a process called angiogenesis - is important in growth, development and wound healing. But it also enables the spread of tumors throughout the body, so researchers have been scrambling for ways to stop angiogenesis in the fight against cancer.

28 Feb 2007

Quantum dots detect metastatic lesions

By injecting quantum dots into tumors, investigators at Carnegie Mellon University have been able to image sentinel lymph nodes in animals using near-infrared light. These results could lead to a simple, non-invasive method for detecting metastasis.

26 Feb 2007

Quantum rods and dots image cancer cells

Brightly fluorescent quantum dots and quantum rods are quickly becoming important tools for identifying specific molecules and cells in living systems. Two new reports demonstrate some of the ways in which cancer researchers are using these nanoscale imaging agents.

26 Feb 2007

How DNA is packed

The life cycles of many viruses include a self-assembly stage in which a powerful molecular motor must pack the DNA genome into the virus's preformed shell (the capsid). How it manages this intricate feat has been subject to debate, but we know that the DNA passes into the capsid shell through a channel formed by a structure called the connector. Scientists have speculated that rotation of the connector complex might feed the DNA into the capsid as it turns.

20 Feb 2007

Nanoparticles advance photodynamic therapy to kill tumor cells

Photodynamic therapy (PDT) is a powerful approach for destroying tumors, one that uses light and a light-sensitive chemical to rapidly kill cells.

20 Feb 2007

Targeting bladder tumor cells in vivo and in the urine with a peptide identified by phage display

Efforts to create nanoparticles that deliver anticancer drugs or imaging agents to tumors while avoiding healthy cells are often stymied by a lack of known tumor targets, that is, molecules found on the surface of malignant cells but not healthy cells.

12 Feb 2007

DNA-encoded antibody libraries

During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

12 Feb 2007

New microscopy technology

Research is finding evidence that may solve one of the great puzzles of 21st Century medicine using a new microscopy technology known as CytoViva.

11 Feb 2007

New, rapid-detection system for Salmonella

The food and drink we consume have to pass strict quality controls. Nevertheless, these measures are not always sufficient, given that sometimes certain foodstuffs can still give rise to food poisoning, most often caused by micro-organisms. The Salmonella bacterium is undoubtedly one of the best known of these.

8 Feb 2007

Scientists step closer to understanding the relationship between aging and cancer

Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome.

6 Feb 2007