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Environmental risk factors driving the nearsightedness 'epidemic' in the UK

A team of researchers used the UK Biobank Study to investigate whether changing environmental factors are causing an increase in myopia.

20 Jan 2022

How does SARS-CoV-2 infection impact female fertility?

In a recent study published in the journal International Journal of Environmental Research and Public Health, a team of researchers reviewed published literature that assessed the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on female reproductive health.

19 Jan 2022

New method reverses insecticide resistance using CRISPR/Cas9 technology

Insecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year. These insect-specific chemicals, which cost more than $100 million to develop and bring to market, also are critical to controlling insect-driven damage on crops that poses a challenge to food security.

18 Jan 2022

"Nocebo effect" accounts for 76% of all adverse events in the COVID-19 vaccine trial group

The placebo effect is the well-known phenomenon of a person's physical or mental health improving after taking a treatment with no pharmacological therapeutic benefit – a sugar pill, or a syringe full of saline, for example.

18 Jan 2022

Improved SARS-CoV-2 surveillance testing with self-collected saliva

The findings from a recent study conducted in the United States suggest that combining saliva with a practical pooling protocol may open the door for easier surveillance testing for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly in resource-limited settings.

18 Jan 2022

Immune responses in Omicron breakthrough COVID-19

A recent study examined the question as to whether vaccination protects against Omicron infection by assessing breakthrough infection rates in participants at a superspreader event.

18 Jan 2022

Quantification of SARS-CoV-2 variants in wastewater samples

In a new study, a team of researchers introduced a novel method to estimate the proportion of different SARS-CoV-2 strains in wastewater samples.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

In a study published in PNAS, researchers have attempted to create a model that can successfully predict which positions are likely to mutate in the future.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

A new study published in the Centers for Disease Control and Prevention’s Emerging Infectious Diseases journal has hypothesized that locations with positive SARS-CoV-2 in sewage could be used as potential surveillance targets to analyze if pestiferous urban rodents shed SARS-CoV-2 into the environment.

16 Jan 2022

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

A new study describes the expected distribution of viral emission of COVID-19 by an infected population of people who were either silent, speaking softly, or loudly, to determine factors influencing risks of viral transmission.

14 Jan 2022

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

A new study, posted to the bioRxiv* preprint server, has developed a single-cell atlas that presents the shared and distinct immune responses and metabolism following SARS-CoV-2 and HIV-1 infections.

13 Jan 2022

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Researchers determine whether sequences within SARS-CoV-2 could lead to an immune response to autoantigens associated with autoimmune myocarditis.

13 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Analysis of COVID vaccine breakthrough infections in highly vaccinated Israel

Researchers evaluated and modeled age-structured cases of SARS-CoV-2 infection, SARS-CoV-2 vaccination coverage, and breakthrough infections.

13 Jan 2022

Investigating the presence of human rRNA in the SARS-CoV-2 genome

In a new study, a team of researchers investigated the existence of SARS-CoV-2-host chimeric RNA and described two novel human-derived genomic insertions present in the circulating variants of SARS-CoV-2.

13 Jan 2022

Forecasting seasonal SARS-CoV-2 mutations

In a study published in Science Translational Medicine, researchers have been trying to create a technique to predict which of these mutations will spread.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Frequency News and Research

Environmental risk factors driving the nearsightedness 'epidemic' in the UK

How does SARS-CoV-2 infection impact female fertility?

New method reverses insecticide resistance using CRISPR/Cas9 technology

"Nocebo effect" accounts for 76% of all adverse events in the COVID-19 vaccine trial group

Improved SARS-CoV-2 surveillance testing with self-collected saliva

Immune responses in Omicron breakthrough COVID-19

Quantification of SARS-CoV-2 variants in wastewater samples

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Virus-like particles as delivery vehicles for gene-editing

Analysis of COVID vaccine breakthrough infections in highly vaccinated Israel

Investigating the presence of human rRNA in the SARS-CoV-2 genome

Forecasting seasonal SARS-CoV-2 mutations

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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