Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Study shows overall prevalence of diabetic kidney disease remains unchanged among U.S. adults

Among U.S. adults with diabetes from 1988 to 2014, the overall prevalence of diabetic kidney disease did not change significantly, while the prevalence of albuminuria declined and the prevalence of reduced estimated glomerular filtration rate increased, according to a study appearing in the August 9 issue of JAMA.

10 Aug 2016

Cerebral protection device reduces brain lesions after TAVI in patients with severe aortic stenosis

Among patients with severe aortic stenosis (narrowing of the aortic valve) undergoing transcatheter aortic valve implantation, the use of a cerebral protection device (a filter that captures debris [tissue and plaque] dislodged during the procedure) reduced the number and volume of brain lesions, according to a study appearing in the August 9 issue of JAMA.

9 Aug 2016

DASH-style diet could help lower risk of developing chronic kidney disease

People who ate a diet high in nuts and legumes, low-fat dairy, whole grains, fruits, and vegetables and low in red and processed meat, sugar-sweetened beverages and sodium were at a significantly lower risk of developing chronic kidney disease over the course of more than two decades, new Johns Hopkins Bloomberg School of Public Health research suggests.

9 Aug 2016

Study finds racial-ethnic disparities in emergency department opioid prescription for pain-related conditions

Dr. Astha Singhal, Assistant Professor in the Department of Health Policy and Health Services Research at Boston University Henry M. Goldman School of Dental Medicine, published a study that found a racial disparity in opioid prescriptions for emergency department visits for non-definitive pain-related conditions.

9 Aug 2016

Study finds no major difference in effectiveness of two classes of drugs in peritoneal dialysis patients

With cardiovascular disease being the No. 1 cause of death in end-stage kidney disease patients on peritoneal dialysis, a new study examined two classes of medications commonly prescribed to prevent cardiovascular events in these patients and found no significant difference in outcomes.

9 Aug 2016

Researcher receives grant to study how changes in gut bacteria could lead to obesity-related disorders

Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.8-million federal grant to study how changes in intestinal bacteria could lead to obesity and metabolic syndrome.

9 Aug 2016

Immunotherapy innovations in oncology: an interview with Robert LaCaze

The body’s immune system is an excellent weapon against many diseases. For more than 100 years, immunology and immunotherapy have played an ever-increasing role in the understanding and treatment of cancer.

8 Aug 2016

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

A research team headed by investigators at the Icahn School of Medicine at Mount Sinai has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell.

5 Aug 2016

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

A combination of three medications—dapagliflozin, liraglutide and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Aug 2016

Watch-and-wait approach may prove successful in subset of adults with advanced kidney cancer

Watch-and-wait approach means some patients could delay taking highly toxic non-curative anticancer drugs that come with substantial side effects

4 Aug 2016

Some WADA-banned substances may have potential medical applications

As the world awaits the start of the 2016 Summer Olympics, doping in athletes remains a hot topic.

4 Aug 2016

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Researchers from the National Institutes of Health and their colleagues identified the genetic cause and a possible therapeutic target for a rare form of pediatric progressive neuropathy.

3 Aug 2016

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Stranger’s organ donation instigates six-way kidney swap

A stranger began a chain of events that eventually saved the lives of six people in desperate need of new kidneys. Her organ donation triggered a six-way kidney swap at Houston Methodist Hospital in July, the second largest of its kind performed at one institution in Texas.

2 Aug 2016

Study examines outcomes of open and robotic partial nephrectomy in patients with kidney tumors

For completely endophytic kidney tumors, which grow inward, both open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) led to excellent patient outcomes in a recent study.

2 Aug 2016

Cell-free DNA test could help identify liver transplant patients with acute rejection

Today, researchers presented findings at the 68th AACC Annual Scientific Meeting that DNA found circulating in the bloodstream—known as cell-free DNA—can be used to identify liver transplant patients with acute rejection with greater accuracy than conventional liver function tests.

1 Aug 2016

DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

DRG International, a leading international medical diagnostic company, will showcase the NEW DRG Hepcidin 25 (bioactive) HS (High Sensitive) ELISA Kit (EIA-5782) at the 2016 AACC in Philadelphia, Pennsylvania from August 02-04.

30 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

Smoking reduces lifespans and overall chances of kidney transplantation in dialysis patients

Dialysis patients who smoke are much less likely to receive a life-saving kidney transplant and much more likely to die sooner according to researchers from the Health Research Institute (HRI) at the University of Limerick and UL’s Graduate Entry Medical School.

29 Jul 2016

Nephrology News and Research

Further Reading

Rare genetic variations linked to severe porphyria

Study shows overall prevalence of diabetic kidney disease remains unchanged among U.S. adults

Cerebral protection device reduces brain lesions after TAVI in patients with severe aortic stenosis

DASH-style diet could help lower risk of developing chronic kidney disease

Study finds racial-ethnic disparities in emergency department opioid prescription for pain-related conditions

Study finds no major difference in effectiveness of two classes of drugs in peritoneal dialysis patients

Researcher receives grant to study how changes in gut bacteria could lead to obesity-related disorders

Immunotherapy innovations in oncology: an interview with Robert LaCaze

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

Watch-and-wait approach may prove successful in subset of adults with advanced kidney cancer

Some WADA-banned substances may have potential medical applications

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Stranger’s organ donation instigates six-way kidney swap

Study examines outcomes of open and robotic partial nephrectomy in patients with kidney tumors

Cell-free DNA test could help identify liver transplant patients with acute rejection

DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

Study clarifies role of KLF12 in CRC tumor growth

Smoking reduces lifespans and overall chances of kidney transplantation in dialysis patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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