Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Novel Alzheimer's risk genes affect microglial response to amyloid-beta

Our DNA determines a large part of our risk for Alzheimer's disease, but it remained unclear how many genetic risk factors contribute to disease.

18 Mar 2020

Researchers elucidate new mechanism for controlling DNA methylation in cells

Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.

17 Mar 2020

Researchers develop new kind of CRISPR screen technology to target RNA

CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases.

16 Mar 2020

Genetic test could help doctors to identify patients with ultra high risk multiple myeloma

A new genetic test could help doctors pick out patients with the bone marrow cancer multiple myeloma who are at 'ultra high risk' of their cancer progressing aggressively early on.

10 Mar 2020

Scientists create new tool to study the genetic underpinnings of brain disorders

Scientists at the UNC School of Medicine and colleagues created a new computational tool called H-MAGMA to study the genetic underpinnings of nine brain disorders, including the identification of new genes associated with each disorder.

9 Mar 2020

Biomarker in saliva linked to emergence of childhood obesity

A molecular marker in saliva is associated with the emergence of childhood obesity in a group of preschool-aged Hispanic children.

7 Mar 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Beating heart muscle tissues to be sent up to the microgravity environment of ISS

Launching no earlier than March 6 at 11:50 PM EST, the Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station for one month of observation.

5 Mar 2020

Researchers establish a gene expression profile associated with cachexia in cancer patients

It is estimated that as many as 80% of advanced-stage cancer patients may develop cachexia, a potentially fatal metabolic syndrome characterized by extreme weight loss and muscle wasting, but scientists do not yet fully understand why it is more frequently associated with certain kinds of tumor than others, or why not all cancer patients develop it.

3 Mar 2020

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

Scientists find link between immune system and high blood pressure in patients with CKD

Detecting threats, sending out response molecules, and altering gene expression--our immune system works tirelessly day and night to protect us from invading pathogens and maintain general health and wellbeing.

3 Mar 2020

Researchers identify major landmarks of peripheral artery disease recovery

Novel biomedical advances that show promise in the lab often fall short in clinical trials. For researchers studying peripheral artery disease, this is made more difficult by a lack of standardized metrics for what recovery looks like.

2 Mar 2020

Nanoparticles containing gliadin could allow celiac disease patients to eat a normal diet

Celiac disease affects 0.3-2.4% of people in most countries world-wide, and approx. 2% in Finland. Celiac patients suffer from a variety of symptoms, typically intestinal complaints, such as diarrhea, but are often symptom-free.

27 Feb 2020

Eating less prolongs life

A new study published in the journal Cell in February 2020 reports that eating less is associated with better immunity, reduce inflammation all over the body, and reduced odds of diseases related to old age, as well as increasing the odds of living longer.

27 Feb 2020

UC researchers uncover potential new treatment for patients with metastatic melanoma

Researchers at the University of Cincinnati have uncovered a potentially more beneficial treatment regimen for patients with metastatic melanoma.

26 Feb 2020

Study identifies novel anti-aging targets

A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets.

26 Feb 2020

Discovery may open up new avenues into improving cancer immunotherapy

New cancer immunotherapy approaches are revolutionizing treatment options for breast cancer patients. However, many lead to insufficient immune responses rendering the therapies incapable of completely eradicating tumors.

23 Feb 2020

Switching what heart cells consume could help them regenerate

Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die, a new study led by UT Southwestern researchers suggests.

23 Feb 2020

Novel discovery about enzymes ensures efficient DNA repair

DNA is the hereditary material in humans, a unique cookbook of who we are. This is where you'll find the answer as to why you have your specific eye and hair color, or perhaps why you sunburn easily.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020