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Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes.

13 Sep 2017

Hormone therapy for menopausal symptoms does not increase mortality risk, according to a long-term study

An 18-year follow-up study of postmenopausal women in the Women’s Health Initiative trials has shown that the use of hormone therapy was not associated with any increased risk of all-cause, cardiovascular or cancer death.

13 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Australian researchers make ultimate move in the battle against melanoma

A team of Australian researchers has made the ultimate move in the battle to beat melanoma, successfully trialing a combination of new treatments to stop the disease in its tracks and prevent it from spreading or metastasizing to distant organs.

12 Sep 2017

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Combination targeted adjuvant therapy with dabrafenib and trametinib doubles relapse-free survival in patients with stage III BRAF-mutant melanoma, according to late-breaking results from the COMBI-AD trial presented today at the ESMO 2017 Congress in Madrid and published in the New England Journal of Medicine.

11 Sep 2017

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

New drug treatment linked to higher bladder compliance after spinal cord injury

Researchers have shown that compared to placebo, a drug treatment intended to prevent remodeling of the bladder wall and given within 48 hours after spinal cord injury (SCI) in dogs was associated with significantly higher bladder compliance.

7 Sep 2017

Cannabidiol appears to protect against long-term negative psychiatric effects of THC

A study reported Sept. 5 by neuroscientists at Indiana University finds that a non-psychoactive compound in cannabis called cannabidiol, or CBD, appears to protect against the long-term negative psychiatric effects of THC, the primary psychoactive ingredient in cannabis.

6 Sep 2017

Testing Service Members for Heat Related Illnesses Before Combat

It is common to think that combat deployment is the most dangerous part of being a warfighter, and in many ways this is correct. However, warfighters need to do many things before they are cleared to deploy to combat zones. Most cases of exertional heat illness (EHI) reported in the U.S. military occur during non-combat activities, such as training regimens, ruck marches, and operational exercises.

From Physitemp Instruments LLC 6 Sep 2017

Zika virus may one day be effective treatment for deadly brain cancer

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer.

5 Sep 2017

Scientists identify and target specific brain area related to ‘hearing voices’ in schizophrenia

For the first time, scientists have precisely identified and targeted an area of the brain which is involved in "hearing voices", experienced by many patients with schizophrenia.

5 Sep 2017

Common heart disease medication may help treat pulmonary arterial hypertension

A team of Cleveland Clinic researchers found that a common heart disease medication, beta blockers, may help treat pulmonary arterial hypertension (PAH), a debilitating lung disease.

31 Aug 2017

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

University of Arizona researchers are collaborating on a Phase 2 trial to determine whether a particular peptide administered before and after coronary bypass surgery mitigates or even reverses cognitive deficits thought to be connected to the procedure.

31 Aug 2017

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

A new study questions the efficacy of treatments for depression based on stimulating brain areas with low-intensity electric current. The technique, known as transcranial direct-current stimulation (tDCS), was considered a promising alternative to treatment with antidepressant drugs.

31 Aug 2017

Study shows metabolic, cardiovascular consequences of untreated sleep apnea

Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects.

31 Aug 2017

CARBS study: Salacia extract provides appetite reduction, satiety and blood sugar management

In the recent CARBS (an acronym for Carbohydrate, Appetite Reduction, Blood Sugar and Satiety) study, researchers at Rutgers University observed that a proprietary salacia extract demonstrated appetite reduction, satiety and blood sugar management benefits.

30 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

Low-dose hormone therapy may be effective in easing sleep issues for recently menopausal women

For many women, the side effects of menopause don't call it a day when they do. Between 40 and 60 percent of women in perimenopause and early menopause face issues with sleep because of this physical change. The majority also report hot flashes and night sweats, which can be disruptive to falling and staying asleep.

29 Aug 2017

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Inclisiran lowers low-density lipoprotein (LDL; "bad") cholesterol for up to one year in patients with high cardiovascular risk and elevated LDL cholesterol, according to late-breaking results from the ORION 1 trial presented today in a Hot Line LBCT Session at ESC Congress.

29 Aug 2017

Placebo News and Research

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

Hormone therapy for menopausal symptoms does not increase mortality risk, according to a long-term study

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Australian researchers make ultimate move in the battle against melanoma

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

New drug treatment linked to higher bladder compliance after spinal cord injury

Cannabidiol appears to protect against long-term negative psychiatric effects of THC

Testing Service Members for Heat Related Illnesses Before Combat

Zika virus may one day be effective treatment for deadly brain cancer

Scientists identify and target specific brain area related to ‘hearing voices’ in schizophrenia

Common heart disease medication may help treat pulmonary arterial hypertension

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

Study shows metabolic, cardiovascular consequences of untreated sleep apnea

CARBS study: Salacia extract provides appetite reduction, satiety and blood sugar management

FDA grants accelerated approval to new treatment for children with Chagas disease

Low-dose hormone therapy may be effective in easing sleep issues for recently menopausal women

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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