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Radical sternectomy could be less risky than conservative

Researchers say that radical sternectomy encompassing the costal cartilages leads to a significantly lower rate of complications and reoperation than conservative sternectomy.

8 Nov 2012

Exercise benefits physical, mental health in schizophrenia

Exercise therapy improves mental health and cardiovascular fitness in patients with schizophrenia, researchers report.

8 Nov 2012

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

immatics biotechnologies GmbH, a biopharmaceutical company developing rationally designed therapeutic vaccines that are active against cancer, announced today that it has completed patient recruitment into the pivotal phase 3 trial evaluating its lead cancer vaccine IMA901 for renal cell carcinoma (RCC). The trial has completed patient inclusion and it is expected that around 345 patients will be randomized across 10 countries in the US and Europe.

8 Nov 2012

Cardiac arrhythmias: an interview with Dr Andrew Grace

Cardiac arrhythmias are disturbances of the heartbeat. The heart can either go too slowly, which might make people collapse or exhausted; or too quickly.

8 Nov 2012

International Day of Radiology marks 117th anniversary of X-ray discovery

International Day of Radiology — November 8, 2012 — marks the 117th anniversary of the discovery of the X-ray and the tremendous advances in patient care made possible by radiation therapy and medical imaging exams, such as MRI and CT scans. It is also a reminder that Congress needs to pass the Diagnostic Imaging Services Access Protection Act (H.R. 3269/ S. 2347) and halt drastic cuts in Medicare funding for imaging scans. This vital legislation would preserve ready access to lifesaving imaging care and may help reduce harm to seniors already resulting from cutbacks.

8 Nov 2012

Autologous stem cells do not improve heart function when given three weeks after heart attack

Administering stem cells derived from patients' own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health (NIH).

8 Nov 2012

Landmark study could lead to fewer inappropriate shocks from implanted defibrillators

Loyola University Medical Center is among the centers participating in a landmark study that could lead to fewer inappropriate shocks from implanted defibrillators.

8 Nov 2012

Radiopharmaceutical Tektrotyd continues to receive interest and recognition

Physicians - attendees of the 25th Annual EANM (European Association of Nuclear Medicine) Congress (October 27-31, Milan) - expressed their continuing interest in and recognition for Tektrotyd, a radiopharmaceutical responsible for significant progress in diagnostics/therapy of neuroendocrine tumours.

8 Nov 2012

Metformin more effective than sulfonylurea in controlling type 2 diabetes

A Vanderbilt study examining the impact of the two most commonly prescribed oral diabetes medications on the risk for heart attack, stroke and death has found the drug metformin has benefits over sulfonylurea drugs.

8 Nov 2012

Thyroid journal publishes new ATA guidelines for management of anaplastic thyroid cancer

Anaplastic thyroid cancer is a rare form of thyroid tumor, but it is also the most deadly. Newly developed evidence-based recommendations for the diagnosis, treatment, and long-term monitoring and follow-up care of patients with this extremely aggressive form of thyroid cancer are published in Thyroid, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

8 Nov 2012

Washington University, SRI investigators launch Global Metabolomic Initiative

Investigators at Washington University and The Scripps Research Institute have announced the launch of a "Global Metabolomic Initiative" to facilitate meta-analyses on studies of the metabolism of bacteria, yeast, plants, animals and people.

7 Nov 2012

Teva announces additional data from QNASL Phase III program on seasonal allergic rhinitis

Teva Pharmaceutical Industries Ltd. announced today that additional data from the Phase III clinical program for QNASL- (beclomethasone dipropionate) Nasal Aerosol will be presented at the 2012 Annual Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Anaheim, CA on November 8-13, 2012.

7 Nov 2012

WU researchers to study blood-clotting disorders

Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

7 Nov 2012

FDA EMDAC votes unanimously in support of Signifor use for treatment of Cushing's disease

The US Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) has voted unanimously in support of the use of Signifor (pasireotide) for the treatment of patients with Cushing's disease who require medical therapeutic intervention.

7 Nov 2012

Cloud technology helps researchers collect detailed information from cancer cell samples

Storing music and photos on distant computers via "cloud" technology is nothing new. But Johns Hopkins researchers are now using this tactic to collect detailed information from thousands of cancer cell samples. The goal is to help doctors make better predictions about how a patient's illness will progress and what type of treatment will be most effective.

7 Nov 2012

Treatment with AMG 145 reduces LDL cholesterol

Amgen today announced that results from the LAPLACE-TIMI 57 and MENDEL Phase 2 studies evaluating AMG 145 in hypercholesterolemic patients with or without statins, respectively, showed that treatment with AMG 145 resulted in a statistically significant reduction in low-density lipoprotein (LDL) cholesterol.

7 Nov 2012

Drug trio may reduce eliminate cardiac side effects of doxorubicin

Combining cancer medication with a drug for erectile dysfunction and one for heart transplants helped kill cancer cells and protected the heart from damage, in a study presented at the American Heart Association's Scientific Sessions 2012.

7 Nov 2012

Lexicon announces data from LX4211 Phase 2b trial on type 2 diabetes

Lexicon Pharmaceuticals, Inc. announced that data from the Phase 2b clinical trial of LX4211 are being presented today as a Clinical Sciences Special Report in the Emerging Therapeutics for Diabetes and Dyslipidemia section of the American Heart Association (AHA) Scientific Sessions Conference held in Los Angeles, California.

7 Nov 2012

Cause of heart attacks or strokes may be different in some patients treated with anti-platelet drugs

The cause of heart attacks or strokes among some patients treated with anti-platelet drugs may be different than for patients who have undergone surgical procedures to restore blood flow, according to researchers at Duke Medicine.

7 Nov 2012

Positive results from BioCardia's Helical Infusion System Phase 1/2 trial on ischemic cardiomyopathy

BioCardia, Inc., focused on regenerative biologic therapies for cardiovascular disease, today announced positive results from a Phase 1/2 heart failure trial using the Company's Helical Infusion System, comprising the Helical Infusion System Catheter and Morph Vascular Access Catheter, to deliver allogeneic, or "off-the-shelf," and autologous, or from the treated patient, mesenchymal (adult) stem cells (MSCs) via transendocardial injection.

7 Nov 2012

Therapy News and Research

Radical sternectomy could be less risky than conservative

Exercise benefits physical, mental health in schizophrenia

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

Cardiac arrhythmias: an interview with Dr Andrew Grace

International Day of Radiology marks 117th anniversary of X-ray discovery

Autologous stem cells do not improve heart function when given three weeks after heart attack

Landmark study could lead to fewer inappropriate shocks from implanted defibrillators

Radiopharmaceutical Tektrotyd continues to receive interest and recognition

Metformin more effective than sulfonylurea in controlling type 2 diabetes

Thyroid journal publishes new ATA guidelines for management of anaplastic thyroid cancer

Washington University, SRI investigators launch Global Metabolomic Initiative

Teva announces additional data from QNASL Phase III program on seasonal allergic rhinitis

WU researchers to study blood-clotting disorders

FDA EMDAC votes unanimously in support of Signifor use for treatment of Cushing's disease

Cloud technology helps researchers collect detailed information from cancer cell samples

Treatment with AMG 145 reduces LDL cholesterol

Drug trio may reduce eliminate cardiac side effects of doxorubicin

Lexicon announces data from LX4211 Phase 2b trial on type 2 diabetes

Cause of heart attacks or strokes may be different in some patients treated with anti-platelet drugs

Positive results from BioCardia's Helical Infusion System Phase 1/2 trial on ischemic cardiomyopathy

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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