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AMG 145 can reduce LDL cholesterol levels by up to 66% after 12 weeks

For many people with high cholesterol, statins serve as the first line of treatment. However, some patients are unable to effectively reduce their low-density lipoprotein cholesterol (LDL cholesterol) or "bad cholesterol" levels with statins, the most commonly used medication to treat high cholesterol, due to their bodies' inability to tolerate or sufficiently respond to the medicine.

7 Nov 2012

Positive results from POZEN's PA32540 Phase 3 trials presented at AHA Scientific Sessions 2012

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, presented positive results from two pivotal Phase 3 clinical trials of the investigational product, PA32540, at The American Heart Association (AHA) Scientific Sessions 2012, as Poster #12057: Treatment Continuation and Cardiovascular Safety of Antiplatelet Therapy with PA32540, A Tablet with Enteric-Coated Aspirin and Immediate-Release Omeprazole: Results of Two 6-Month, Phase 3 Studies.

6 Nov 2012

$Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina$

Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina

Cryopraxis/CellPraxis aims to start patient recruitment for its Phase III Refractory Angina Cell Therapy Brazilian arm clinical trial by the end of 2012 or early 2013.

6 Nov 2012

Monoclonal antibody boosts cholesterol reduction

Adding a monoclonal antibody that blocks the breakdown of lipid receptors to atorvastatin therapy further reduces low-density lipoprotein cholesterol levels in patients with primary hypercholesterolemia, show study findings.

6 Nov 2012

Stressful life events linked to bipolar depression

Stressful life events, particularly independent severe, loss, and danger events, are significantly associated with depressive symptoms in patients with bipolar disorder, study results show.

6 Nov 2012

Exercise not superior to physiotherapy for neck pain

Both exercise-based interventions and physiotherapy are effective for reducing pain in patients with nonspecific neck pain, UK researchers have found, but adherence to such treatments remains a challenge.

6 Nov 2012

Receptor expression sheds light on nasal polyposis

The increased expression of a leukotriene receptor and a glucocorticoid receptor may contribute to the development of nasal polyposis, report researchers.

6 Nov 2012

Physical exercise may help preserve mobility in Parkinson’s patients

Aerobic and resistance exercise significantly improve fitness, gait speed, and muscle strength in patients with Parkinson’s disease, shows research published in the Archives of Neurology.

6 Nov 2012

Comprehensive overview of vascular risk factors to Alzheimer's disease

Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer's disease.

6 Nov 2012

Fracture bracing systems: an interview with Steve Ingel, President for the Bracing & Supports Division of DJO Global

Surprisingly, there are significantly more medical treatment episodes for upper extremity fractures than for those of lower extremity. The vast majority of forearm, hand and wrist fractures occur in pediatrics and young adults as they tend to be more active and involved in sporting activities.

6 Nov 2012

Gene silencing technology used to fight RSV and influenza

New hope has arrived for the fight against two deadly viral infections, RSV and influenza, as Griffith researchers prepare to develop a cutting-edge approach to treatment delivery.

6 Nov 2012

Low-dose aspirin effective at preventing serious blood clots

Low-dose aspirin is a cheap and effective way to prevent potentially deadly blood clots in the leg or the lungs in patients who have had a previous blood clot a new study shows.

6 Nov 2012

Study shows how local anesthetics can improve motor skills of patients after stroke

Painkilling drugs that make many therapies possible are a blessing for patients. Thanks to modern anesthetics, not only can surgical operations be conducted without causing pain, they are also used for various diagnostic procedures. Anesthetics can be very useful in therapies for stroke patients, as psychologists and physicians of the Friedrich Schiller University Jena (Germany) and the University Hospital Jena are now able to prove.

6 Nov 2012

Patients with diabetes, multi-vessel coronary artery disease can benefit from bypass surgery

An international, clinical research trial has shown that patients with diabetes whose multi-vessel coronary artery disease is treated with bypass surgery live longer and are less likely to suffer severe complications like heart attacks than those who undergo angioplasty.

6 Nov 2012

Therapy News and Research

AMG 145 can reduce LDL cholesterol levels by up to 66% after 12 weeks

Positive results from POZEN's PA32540 Phase 3 trials presented at AHA Scientific Sessions 2012

Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina

Monoclonal antibody boosts cholesterol reduction

Stressful life events linked to bipolar depression

Exercise not superior to physiotherapy for neck pain

Receptor expression sheds light on nasal polyposis

Physical exercise may help preserve mobility in Parkinson’s patients

Comprehensive overview of vascular risk factors to Alzheimer's disease

Fracture bracing systems: an interview with Steve Ingel, President for the Bracing & Supports Division of DJO Global

Gene silencing technology used to fight RSV and influenza

Low-dose aspirin effective at preventing serious blood clots

Study shows how local anesthetics can improve motor skills of patients after stroke

Patients with diabetes, multi-vessel coronary artery disease can benefit from bypass surgery

Intravenous infusion of HDL cholesterol could reduce risk of subsequent heart attack

Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer

Living liver donors have QoL advantage

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Imaging-based therapy benefits ‘wake-up stroke’ patients

Rush’s AARTS program to improve quality of life of children and adults with autism

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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