Therapy News and Research

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Pradaxa use does not appear to increase serious bleeding

The U.S. Food and Drug Administration (FDA) today announced the results of a Mini-Sentinel assessment that indicates bleeding rates associated with new use of Pradaxa (dabigatran etexilate mesylate) capsules do not appear to be higher than bleeding rates associated with new use of warfarin, which is consistent with observations from the pivotal RE-LY trial.

4 Nov 2012

New information related to kidney transplantation

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information related to kidney transplantation—specifically, the post-transplant health of kidney donors and the racial disparities faced by children in need of transplants.

3 Nov 2012

One-day seminar to explore ophthalmic innovations

The newest ophthalmic innovations with market potential will be the focus of a one-day seminar in Seattle on May 3, 2013 that will connect scientists, venture capitalists, pharmaceutical representatives and others.

3 Nov 2012

Caltech-led team discovers enzyme responsible for neural crest cell development

During the early developmental stages of vertebrates-animals that have a backbone and spinal column, including humans-cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types.

3 Nov 2012

TeleMedTM announces launch of TeleMedTM Psychiatry

TeleMedTM announces the launch of TeleMedTM Psychiatry, a first-of-its-kind telepsychiatry solution designed to give mental health providers and patients scheduled access to one another through secure online video therapy, regardless of location.

3 Nov 2012

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Portola Pharmaceuticals, Inc., Bristol-Myers Squibb Company and Pfizer Inc. today announced a clinical collaboration agreement to conduct a proof-of-concept study of PRT4445 and the investigational oral Factor Xa inhibitor ELIQUIS (apixaban).

3 Nov 2012

Lomitapide shows promise in treating homozygous familial hypercholesterolemia

An international effort led by researchers at the Perelman School of Medicine at the University of Pennsylvania has resulted in positive phase 3 clinical trial results for a new medicine to treat patients suffering from a rare and deadly cholesterol disorder.

3 Nov 2012

Autism interventions are supported by varying levels of evidence, reveals new RAND study

Interventions designed to improve core deficits in children with autism spectrum disorders are supported by varying levels of evidence, highlighting the need for well-designed studies to better evaluate the interventions, according to a new RAND Corporation study.

3 Nov 2012

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease.

3 Nov 2012

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say.

3 Nov 2012

Viewpoints: Romney, Obama offer their 'visions for America;' One liberal wary of Mass. effort on assisted suicide

Change is an America where we reduce our deficit by cutting spending where we can, and asking the wealthiest Americans to go back to the income tax rates they paid when Bill Clinton was president. I've worked with Republicans to cut a trillion dollars of spending, and I'll do more. I'll work with anyone of any party to move this country forward. But I won't agree to eliminate health insurance for millions of poor, elderly, or disabled on Medicaid, or turn Medicare into a voucher just to pay for another millionaire's tax cut.

3 Nov 2012

Men with prostate cancer can benefit from active surveillance

With active surveillance many men with prostate cancer could dispense with radiation treatment and surgery, and thus avoid adverse effects such as incontinence and impotence. This is the outcome of a study of almost 1,000 men diagnosed with prostate cancer conducted at Sahlgrenska Academy, University of Gothenburg, Sweden.

3 Nov 2012

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

The U.S. Food and Drug Administration today expanded the approved use of Xarelto (rivaroxaban) to include treating deep vein thrombosis (DVT) or pulmonary embolism (PE), and to reduce the risk of recurrent DVT and PE following initial treatment.

3 Nov 2012

Studies provide new information on diet and blood pressure in kidney disease patients

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on diet and blood pressure in kidney disease patients.

3 Nov 2012

AeriSeal System appears to be effective in treating emphysema

Researchers at the University of Alabama at Birmingham injected a foam sealant into the lungs of a former smoker on Oct. 29, 2012, to treat his worsening emphysema. He was the first patient in the United States treated in a late-stage clinical trial of the AeriSeal System.

3 Nov 2012

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

A Medicare rule that blocks thousands of nursing home residents from receiving simultaneous reimbursement for hospice and skilled nursing facility care at the end of life may result in those residents receiving more aggressive treatment and hospitalization, according a new analysis.

3 Nov 2012

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD).

3 Nov 2012

Near-complete blood flow restoration necessary to preserve neurological function following stroke

Two Rhode Island Hospital researchers recently found that restoring near-complete blood flow to the brain is necessary to restore or preserve neurological function following stroke. Seems like a no-brainer, right? Yet until their research was complete, many physicians and researchers believed that partial blood-flow restoration was good enough. Not anymore.

3 Nov 2012

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen.

From The University of Manchester 3 Nov 2012

Radiosurgery alone can achieve local control of brain metastases

Radiosurgery to the surgical cavity without whole-brain radiotherapy achieves good rates of local control in patients with brain cancer metastases, a study has shown.

2 Nov 2012

Therapy News and Research

Pradaxa use does not appear to increase serious bleeding

New information related to kidney transplantation

One-day seminar to explore ophthalmic innovations

Caltech-led team discovers enzyme responsible for neural crest cell development

TeleMedTM announces launch of TeleMedTM Psychiatry

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Lomitapide shows promise in treating homozygous familial hypercholesterolemia

Autism interventions are supported by varying levels of evidence, reveals new RAND study

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

Viewpoints: Romney, Obama offer their 'visions for America;' One liberal wary of Mass. effort on assisted suicide

Men with prostate cancer can benefit from active surveillance

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

Studies provide new information on diet and blood pressure in kidney disease patients

AeriSeal System appears to be effective in treating emphysema

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

Near-complete blood flow restoration necessary to preserve neurological function following stroke

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

Radiosurgery alone can achieve local control of brain metastases

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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