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Study shows increased risk of local recurrence in women with triple negative breast cancer

Research from The Cancer Institute of New Jersey (CINJ) shows that women with triple-negative breast cancer and no more than three positive lymph nodes following a mastectomy have a higher risk of local recurrence than similar women whose disease is not classified as triple-negative.

1 Nov 2012

Encouraging results from Gilead’s TAF Phase 2 trial on HIV-1 infection

Gilead Sciences, Inc. today announced that a Phase 2 clinical trial evaluating tenofovir alafenamide fumarate, an investigational novel prodrug of tenofovir for the treatment of HIV-1 infection, met its primary objective.

1 Nov 2012

Encouraging results from stereotactic radiosurgery Phase I trial on kidney cancer

A first-of-its-kind clinical trial conducted at University Hospitals (UH) Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer.

1 Nov 2012

Exosomes alone could protect infants' lungs from dangerous inflammation

Researchers at Boston Children's Hospital have found that microscopic particles containing proteins and nucleic acids called exosomes could potentially protect the fragile lungs of premature babies from serious lung diseases and chronic lung injury caused by inflammation.

1 Nov 2012

Single dose of etanercept can improve chronic neurological dysfunction from stroke or TBI

A new ground-breaking study about to be published in the Adis journal CNS Drugs provides clinical evidence that, for the first time, chronic neurological dysfunction from stroke or traumatic brain injury can rapidly improve following a single dose of a drug that targets brain inflammation, even years after the stroke or traumatic event.

1 Nov 2012

Advaxis updates preliminary data from ADXS-HPV Phase 2 trial on cervical cancer

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, updated preliminary data from an ongoing randomized 110 patient Phase 2 trial of ADXS-HPV being conducted in India in women with recurrent/refractory cervical cancer who have failed previous cytotoxic therapy.

1 Nov 2012

New index can help clinicians assess patients' prosthetic arm progress

Amputees with a new prosthetic arm must learn how to use their device to perform everyday tasks that were once second nature. Taking off a shirt becomes a conscious, multistep effort: grasp the shirt, lift the shirt over the head, pull arms through the sleeves, place the shirt on the table, let go of the shirt.

1 Nov 2012

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Varian Medical Systems highlighted the company's technologies for the non-invasive treatment of lung cancer at the 54th annual meeting of the American Society for Radiation Oncology (ASTRO) in Boston this week.

1 Nov 2012

Recurrence risk can be identified before hepatectomy

Patients who are likely to experience disease recurrence after undergoing hepatectomy for hepatocellular carcinoma can be identified by factors that are available preoperatively, indicate the results of a Hong Kong study.

31 Oct 2012

Prognostic impact of Gleason score modernization undetermined

A review of contemporary grading systems for prostate cancer has found that modernization of the Gleason grading system results in more accurate grading for radical prostatectomy than older systems.

31 Oct 2012

Gene variant predicts lymphoma treatment response

German researchers have identified a gene variant that significantly influences the outcome of methotrexate therapy for primary central nervous system lymphoma.

31 Oct 2012

SSRIs should be prescribed with great caution to those attempting to get pregnant

Elevated risk of miscarriage, preterm birth, neonatal health complications and possible longer term neurobehavioral abnormalities, including autism, suggest that a class of antidepressants known as selective serotonin reuptake inhibitors (SSRI) should only be prescribed with great caution and with full counseling for women experiencing depression and attempting to get pregnant, say researchers at Beth Israel Deaconess Medical Center, Tufts Medical Center and MetroWest Medical Center.

31 Oct 2012

Uterine cancer recurrence risk after hysterectomy increases due to delay in radiation therapy

Waiting too long after a hysterectomy to begin radiation therapy may increase the risk of uterine cancer recurrence, according to a new study from researchers at Henry Ford Hospital in Detroit.

31 Oct 2012

Cost of searching for fountain of youth exceeds cost for medications to treat chronic disease

The cost of searching for the fountain of youth has become increasingly expensive and now exceeds the cost for medications used to treat chronic disease, according to new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif.

31 Oct 2012

SSRIs should be prescribed with great caution to those attempting to get pregnant

31 Oct 2012

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate.

31 Oct 2012

Hormone therapy increases risk of heart attack or dying in women with metabolic syndrome

A new analysis of the Women's Health Initiative (WHI) trials show that women who had metabolic syndrome before they started hormone therapy had a greatly increased risk of heart attack or dying of heart disease. Women who didn't have metabolic syndrome beforehand showed no increased risk.

31 Oct 2012

Blocking RSK protein activity could improve treatment of skin cancers

Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC).

31 Oct 2012

Technology creates 3-D map of stresses linked to malformed structures

Researchers at Case Western Reserve University have found a way to create three-dimensional maps of the stress that circulating blood places on the developing heart in an animal model - a key to understanding triggers of heart defects.

31 Oct 2012

Bronchial thermoplasty helps control severe asthma

Nearly 24 million people in this country suffer from asthma. For most of them, avoiding allergens and taking medications help keep their asthma under control. But for a small group with severe persistent asthma, frequent hospital visits tend to be the norm and taking medications and lifestyle changes don't do the trick. Northwestern Memorial Hospital is now using a new procedure called bronchial thermoplasty (BT), the first non-drug therapy approved by the Federal Drug Administration, for patients with severe asthma.

31 Oct 2012

Therapy News and Research

Study shows increased risk of local recurrence in women with triple negative breast cancer

Encouraging results from Gilead’s TAF Phase 2 trial on HIV-1 infection

Encouraging results from stereotactic radiosurgery Phase I trial on kidney cancer

Exosomes alone could protect infants' lungs from dangerous inflammation

Single dose of etanercept can improve chronic neurological dysfunction from stroke or TBI

Advaxis updates preliminary data from ADXS-HPV Phase 2 trial on cervical cancer

New index can help clinicians assess patients' prosthetic arm progress

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Recurrence risk can be identified before hepatectomy

Prognostic impact of Gleason score modernization undetermined

Gene variant predicts lymphoma treatment response

SSRIs should be prescribed with great caution to those attempting to get pregnant

Uterine cancer recurrence risk after hysterectomy increases due to delay in radiation therapy

Cost of searching for fountain of youth exceeds cost for medications to treat chronic disease

SSRIs should be prescribed with great caution to those attempting to get pregnant

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

Hormone therapy increases risk of heart attack or dying in women with metabolic syndrome

Blocking RSK protein activity could improve treatment of skin cancers

Technology creates 3-D map of stresses linked to malformed structures

Bronchial thermoplasty helps control severe asthma

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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