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New hope for mitochondrial disease sufferers

Scientists have succeeded in replacing mitochondrial DNA in human oocytes, which they hope will lead to the procedure being developed for use in patients with mitochondrial diseases.

29 Oct 2012

Aspirin improves colorectal cancer survival in tandem with gene mutation

Aspirin significantly improves survival in colorectal cancer patients who have a mutation in a carcinogenesis-associated signaling pathway, the results of a US and Japanese study indicate.

29 Oct 2012

Carotid ultrasound improves risk management in rheumatoid arthritis

A trial of radiofrequency ultrasound in patients with rheumatoid arthritis has shown that carotid intima-media thickness is significantly greater in patients treated only with synthetic therapeutics compared with those who are also taking biologics.

29 Oct 2012

Positive interim data from XBiotech monoclonal antibody Phase II study for type 2 diabetes

XBiotech, a privately held biotechnology company, announced positive interim analysis results today from a Phase II study using a True Human monoclonal antibody (MABp1) in patients with type 2 diabetes. Results from this study continue to reinforce the role of IL-1α as a master regulator of chronic inflammation in multiple disease states, and the therapeutic benefits of neutralizing antibodies produced from the XBiotech platform.

29 Oct 2012

Antidepressant doxepin eases pain associated with oral mucositis

An oral rinse of the antidepressant doxepin significantly eased pain associated with oral mucositis in patients receiving radiation therapy for cancers of the head and neck, a study led by Mayo Clinic found. The findings were presented at the American Society for Radiation Oncology annual meeting in Boston.

29 Oct 2012

New prostate cancer therapy triggers questions about cost, effectiveness and safety

Because proton therapy can be targeted much more precisely, it should minimize any damage to sensitive nerves and tissue around the prostate.

29 Oct 2012

Botanical treatment holds hope for triple-negative breast cancer

A unique formula made from medicinal mushrooms, traditional Chinese herbs and other natural ingredients inhibits aggressive, human triple-negative breast cancer and breast-to-lung metastasis in mice. This is the third peer-reviewed study to demonstrate the botanical formula's anticancer effects.

29 Oct 2012

AstraZeneca commences FASLODEX Phase III study for hormone receptor-positive metastatic breast cancer

AstraZeneca today announced the start of a Phase III study (FALCON), a global clinical trial which will involve 450 postmenopausal patients with hormone receptor-positive locally advanced or metastatic breast cancer who have not previously been treated with any hormonal therapy. The Phase III study is designed to evaluate the efficacy and tolerability of fulvestrant 500 mg compared to anastrozole 1 mg in this patient population.

29 Oct 2012

Nonclinical data on Provectus PV-10 oncology drug presented at 27th SITC

Provectus Pharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, presented nonclinical data on PV-10 at the Society for Immunotherapy of Cancer (SITC) 27th Annual Meeting on October 26 and 27, 2012 in North Bethesda, MD.

29 Oct 2012

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Sea water therapy is a technique of cellular nutrition backed by more than 100 years of clinical use in hospitals, during which numerous studies have demonstrated its beneficial effects on patients' health.

29 Oct 2012

Cellectis announces successful programming of immune system cells to kill cancer cells

Cellectis, the genome engineering specialist, has announced successfully programming cells from the immune system (T cells) to kill cancer cells. This technological breakthrough was revealed for the first time ever on Saturday, October 27th at the congress of the ESGCT (European Society of Gene & Cell Therapy) in Versailles, outside Paris.

29 Oct 2012

Tumor count in the breast an important consideration for providing radiation therapy

Not all women diagnosed with operable breast cancer present with a single tumor; some have multifocal disease appear in the breast, which means multiple tumors found in the same breast quadrant, while others have multicentric disease, where multiple tumors are found in separate breast quadrants. Multifocal or multicentric disease is not a standard indication to receive radiation after mastectomy. For patients who undergo lumpectomy, radiation dose and extent is not altered based on multifocal or multicentric disease compared to patients presenting with a single tumor.

29 Oct 2012

Alternate method to precisely tag breast cancer tumors

When surgeons operate to remove a tumor, determining exactly where to cut can be tricky. Ideally, the entire tumor should be removed while leaving a continuous layer of healthy tissue, but current techniques for locating the tumors during surgery are imprecise. Now a multidisciplinary team from the University of California, San Diego, is developing an alternate means of precisely tagging breast cancer tumors for removal or targeted destruction.

29 Oct 2012

First Edition: October 29, 2012

Today's headlines include reports about how the presidential election's outcome could impact the insurance industry as well as the fate of people who are sick or uninsured.

29 Oct 2012

New therapy to treat rare form of cystic fibrosis works in unconventional way, scientists say

Scientists at the Hospital for Sick Children in Toronto have established that a drug recently approved by the U.S. Food and Drug Administration to treat a rare form of cystic fibrosis works in an unconventional way.

29 Oct 2012

UK remains at risk of devastating stroke crisis, new report confirms

The UK remains at risk of a devastating stroke crisis, according to UK health experts launching Reports published today, on World Stroke Day, by Action for Stroke Prevention, an alliance of renowned health experts and patient organisations.

29 Oct 2012

FDA clears MAQUET’s new SENSATION PLUS 7.5Fr. 40cc intra-aortic balloon catheter

MAQUET Cardiovascular LLC, a leading provider of cardiovascular technologies, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) and CE mark approval for its new SENSATION PLUS 7.5Fr. 40cc intra-aortic balloon (IAB) catheter.

29 Oct 2012

Drug-eluting stents exhibit some benefits in patients over 80

Rarely tested in patients over the age of 80, a study found that drug-eluting stents exhibited some benefits over bare-metal stents, though both types of stents demonstrated a clinical benefit. Results of the XIMA trial were presented today at the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

29 Oct 2012

New research report shows how bimatoprost causes human hair to regrow

If you're balding and want your hair to grow back, then here is some good news. A new research report appearing online in The FASEB Journal shows how the FDA-approved glaucoma drug, bimatoprost, causes human hair to regrow.

29 Oct 2012

New findings on early treatment of ADHD patients presented at AACAP 2012 conference

Mayo Clinic researchers are presenting new findings on the early treatment of child and adolescent attention deficit hyperactivity disorder this week at the American Academy of Childhood and Adolescent Psychiatry annual meeting in San Francisco.

29 Oct 2012

Therapy News and Research

New hope for mitochondrial disease sufferers

Aspirin improves colorectal cancer survival in tandem with gene mutation

Carotid ultrasound improves risk management in rheumatoid arthritis

Positive interim data from XBiotech monoclonal antibody Phase II study for type 2 diabetes

Antidepressant doxepin eases pain associated with oral mucositis

New prostate cancer therapy triggers questions about cost, effectiveness and safety

Botanical treatment holds hope for triple-negative breast cancer

AstraZeneca commences FASLODEX Phase III study for hormone receptor-positive metastatic breast cancer

Nonclinical data on Provectus PV-10 oncology drug presented at 27th SITC

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Cellectis announces successful programming of immune system cells to kill cancer cells

Tumor count in the breast an important consideration for providing radiation therapy

Alternate method to precisely tag breast cancer tumors

First Edition: October 29, 2012

New therapy to treat rare form of cystic fibrosis works in unconventional way, scientists say

UK remains at risk of devastating stroke crisis, new report confirms

FDA clears MAQUET’s new SENSATION PLUS 7.5Fr. 40cc intra-aortic balloon catheter

Drug-eluting stents exhibit some benefits in patients over 80

New research report shows how bimatoprost causes human hair to regrow

New findings on early treatment of ADHD patients presented at AACAP 2012 conference

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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