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Dedicated web site for PKU medical education to be launched at 2010 SSIEM Annual Symposium

PKU specialists around the world can now count on a brand-new, authoritative website entirely dedicated to this rare genetic disorder, which affects one out of every 10,000 to 20,000 live births worldwide.

31 Aug 2010

Genetic profiling to predict treatment benefits of ACE inhibitor therapy for CAD

The advantages of prescribing angiotensin-converting enzyme (ACE) inhibitors for stable coronary artery disease (CAD) may be increased by targeting the therapy to the patients most likely to benefit.Clinical characteristics alone do not allow a reliable identification of these patients, so a research programme was carried out at Erasmus University Medical Centre in Rotterdam to develop a genetic profiling model that predicts the treatment benefits of ACE inhibitors and optimises the recommended therapy.

31 Aug 2010

Advanced Cell Technology updates transdifferentiation plans to enhance regenerative medicine

Advanced Cell Technology, Inc. provides an update today on its plans to utilize its transdifferentiation platform to enhance regenerative medicine.

31 Aug 2010

African-Americans at higher risk of developing stent thrombosis

African-American race is a distinct risk factor for developing life-threatening blood clots after receiving a drug-coated stent, according to research reported in Circulation: Journal of the American Heart Association.

31 Aug 2010

Cell Therapy Foundation analysis calls for funding in medical research

Some of the most promising medical research conducted to treat diseases of the brain, heart, and circulatory system is moving too slowly to help millions of patients, according to the Cell Therapy Foundation, which advocates the use of adult stem cells to dramatically impact and improve the condition of patients who suffer from a variety of conditions.

31 Aug 2010

Genetic variations in Y chromosome affect men's risk of coronary heart disease: Scientists

Scientists in the UK have shown that genetic variations in the Y chromosome affect a male's risk of coronary heart disease. It is well known that males have a higher incidence of coronary heart disease than females due, in part, to the Y chromosome they inherit from their fathers. To investigate the role of the Y chromosome further, a team from the University of Leicester carried out research to determine whether genetic variations in the Y-chromosome affect risk for males.

30 Aug 2010

Latest achievements in brain research and treatment for mental disorders

Mental disorders, such as depression, anxiety disorders, addiction and schizophrenia are the core challenge of most health care systems around the world. In the EU alone, each year 27% of the total adult population - this corresponds to 83 Million citizens - suffer from mental disorders. Depression alone affects almost 20 million ranking in the EU as the most disabling disorder of all diseases.

30 Aug 2010

23rd ECNP Congress press conference

The incidence of psychotic disorders varies greatly across places and demographic groups, as do symptoms, course, and treatment response across individuals. High rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatised individuals reflect the causal influence of environmental exposures. This, in combination with progress in the area of molecular genetics, has generated interest in more complicated models of schizophrenia aetiology that explicitly posit gene-environment interactions.

30 Aug 2010

New research contradicts previous reports on blood-thinner clopidogrel

New findings by McMaster University researchers contradict earlier reports that people with a certain genetic make-up don't benefit from the blood-thinner clopidogrel, also known as Plavix.

30 Aug 2010

Cancer Research UK data finds increase in Oesophageal cancer rates among men

Oesophageal cancer rates in men have risen by 50 per cent over the last 25 years, according to new figures published by Cancer Research UK today.In 1983 around 2,600 men were diagnosed with oesophageal cancer - cancer of the food pipe - and according to the latest figures around 5,100 men were diagnosed with the disease.

30 Aug 2010

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists at Jefferson Medical College have received a four-year, $3 million National Institutes of Health grant funded by the National Heart, Lung and Blood Institute to study variations of platelet function, specifically, the genetics of platelet gene expression. The study aims to find data that can be translated into novel therapeutic strategies and develop better predictors of cardiovascular disease.

30 Aug 2010

Scientists develop new combined treatment method for skin cancer prevention

Scientists at The University of Texas Health Science Center San Antonio are on to something that should bring joy to sunbathers everywhere. Studies show that certain plant substances, administered in combinations, have the ability to suppress skin cancer development in susceptible mice.

30 Aug 2010

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.The study may help in the search for future therapeutic strategies to fight a growing medical problem that currently lacks effective treatments, researchers from Cincinnati Children's Hospital Medical Center report in the Aug. 29 Nature Immunology.

30 Aug 2010

New high throughput sequencing technology to identify genetic defects in rare diseases

The majority of rare diseases are hereditary. But despite significant progress in genome research, in most cases their exact cause remains unclear. The discovery of the underlying genetic defect is, however, a prerequisite for their definitive diagnosis and the development of innovative approaches to their treatment. Scientists at the Max Planck Institute for Molecular Genetics and the Institute of Medical Genetics at the Charit- Universit-tsmedizin - Berlin have succeeded in using a new process with which all of the genes in the human genome can be analysed simultaneously.

30 Aug 2010

Study reveals impact of genetic make-up on response to oral antiplatelet treatment ticagrelor

A new genetic substudy of PLATO showed that the effects on a combined primary endpoint of cardiovascular death, myocardial infarction, or stroke seen in Acute Coronary Syndromes patients who received the investigational oral antiplatelet treatment, ticagrelor (BRILINTA), were maintained, whether or not they had the genetic variability that has been previously shown to affect a patient's response to clopidogrel.

30 Aug 2010

GWAS finds new genetic link between Parkinson's disease and inflammation

A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development.

30 Aug 2010

Shire receives European marketing approval for VPRIV therapy to treat type 1 Gaucher disease

Shire, the global specialty biopharmaceutical company, announced today that the European Commission has granted marketing authorisation for VPRIV(R) (velaglucerase alfa), a human cell line derived enzyme replacement therapy (ERT) for the long-term treatment of type 1 Gaucher disease.

27 Aug 2010

Light signaling pathways, circadian rhythms affect biological functions: Research

A new study of the genetic basis of circadian rhythms - the biological responses related to daily light exposure - has found that a few minutes of light exposure in a fungus directly affects a huge range of its biological functions, everything from reproduction to coloring and DNA repair.

27 Aug 2010

Luminex launches FDA-cleared xTAG Cystic Fibrosis 60 Kit v2 diagnostic test

Luminex Corporation, the worldwide leader in multiplexed solutions, today announced the full commercial launch of its xTAG Cystic Fibrosis 60 Kit v2, a new diagnostic test that can simultaneously screen a single blood sample for up to 60 cystic fibrosis-causing genetic mutations in a matter of hours.

From Thermo Fisher Scientific Inc. 27 Aug 2010

New York State permits Genelex Corporation's DNA Drug Sensitivity Tests

The New York State Department of Health has licensed Genelex Corporation's DNA Drug Sensitivity Tests for use by doctors in the state. The issued Clinical Laboratory Permit is for DNA testing of three enzymes, the cytochrome P450s, that process more than 50 percent of the most commonly prescribed medicines.

27 Aug 2010

Genetic News and Research

Dedicated web site for PKU medical education to be launched at 2010 SSIEM Annual Symposium

Genetic profiling to predict treatment benefits of ACE inhibitor therapy for CAD

Advanced Cell Technology updates transdifferentiation plans to enhance regenerative medicine

African-Americans at higher risk of developing stent thrombosis

Cell Therapy Foundation analysis calls for funding in medical research

Genetic variations in Y chromosome affect men's risk of coronary heart disease: Scientists

Latest achievements in brain research and treatment for mental disorders

23rd ECNP Congress press conference

New research contradicts previous reports on blood-thinner clopidogrel

Cancer Research UK data finds increase in Oesophageal cancer rates among men

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists develop new combined treatment method for skin cancer prevention

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

New high throughput sequencing technology to identify genetic defects in rare diseases

Study reveals impact of genetic make-up on response to oral antiplatelet treatment ticagrelor

GWAS finds new genetic link between Parkinson's disease and inflammation

Shire receives European marketing approval for VPRIV therapy to treat type 1 Gaucher disease

Light signaling pathways, circadian rhythms affect biological functions: Research

Luminex launches FDA-cleared xTAG Cystic Fibrosis 60 Kit v2 diagnostic test

New York State permits Genelex Corporation's DNA Drug Sensitivity Tests

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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