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CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and linked to tumor progression, but its role in lung squamous-cell carcinoma (LUSC) remained unclear.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Psilocybin rewires the brain for weeks, study finds

Psilocybin induces consistent and sustained changes in brain network connectivity, particularly between the hippocampus and default mode network, as shown using high-resolution fMRI in healthy adults. These neural effects, distinct from those produced by methylphenidate, may underlie the drug’s psychological benefits and were reproducible within individuals over time.

10 Jun 2025

Methylation clocks may mislead anti-aging therapy evaluation

A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions."

10 Jun 2025

Symptom asymmetry influences how Parkinson’s patients process emotions

New study shows dopamine treatments and symptom asymmetry impact patients differently.

10 Jun 2025

Dr. Stephen Ross’s research into psychedelic medicine expands therapeutic frontiers

In a comprehensive Genomic Press Interview published today, Dr. Stephen Ross, a leading figure in psychedelic medicine at New York University (NYU), reveals how a serendipitous conversation in 2006 launched his journey into investigating psychedelic compounds as potential breakthrough treatments for some of psychiatry's most challenging conditions.

10 Jun 2025

Centauri Therapeutics publishes proof-of-concept data demonstrating activity of a novel bifunctional immunotherapy against Gram-negative bacterial infections

Centauri Therapeutics Limited (Centauri), an immunotherapy company with a unique and proprietary platform technology applicable across a wide range of therapeutic indications, today announced the publication of a peer-reviewed study in The Journal of Immunology.

10 Jun 2025

Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer

A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer – and offers a potential pathway for new treatments.

9 Jun 2025

Nearly half of breast cancer patients continue hormone therapy beyond five years

As recommendations suggest extending hormone-based breast cancer treatment to 10 years for some patients, a new study sheds light on whether patients are opting for it.

9 Jun 2025

Spatial transcriptomics could transform musculoskeletal research

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

9 Jun 2025

Glioblastoma patients live longer with triple treatment strategy

A new study led by Keck Medicine of USC researchers may have uncovered an effective combination therapy for glioblastoma, a brain tumor diagnosis with few available effective treatments.

9 Jun 2025

Brain state-driven neural stimulation improves cognitive flexibility and relieves autistic behaviors

Some autistic traits related to challenges with social interaction, mental flexibility and visual perception could be alleviated through a new, noninvasive therapy.

9 Jun 2025

Breakthrough tumor profiling study offers hope for more precise skin cancer care

Every tumor is unique. This makes it difficult to find the most effective therapy for treatment. The Tumor Profiler Center of the University Hospital Zurich, the University of Zurich, ETH Zurich and the University Hospital Basel has now carried out a study in which nine different molecular biological technologies were used to precisely measure the properties of the tumor in four weeks and enable a precise treatment decision.

6 Jun 2025

Genetic mutation tied to Crohn's disease can worsen iron deficiency and anemia

A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn's disease can worsen iron deficiency and anemia - one of the most common complications experienced by patients with inflammatory bowel disease, or IBD.

6 Jun 2025